The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB

Zhou Ying

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Zhou Ying . The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB[J]. Journal of Kunming Medical University, 2016, 37(04).

Citation:

Zhou Ying . The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB[J]. Journal of Kunming Medical University, 2016, 37(04).

Zhou Ying . The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB[J]. Journal of Kunming Medical University, 2016, 37(04).

Citation:

Zhou Ying . The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB[J]. Journal of Kunming Medical University, 2016, 37(04).

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The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB

Zhou Ying

(1)The First People’s Hospital of Xiantao Hubei,Xiantao Hubei 433000;2)Wuhan Institute of Technology,Wuhan Hubei 430032,China)

Abstract

Abstract

［Abstract］Objective To observe the influence of glutathion（GSH）combined entecavir（ETV） on the serum levels of liver fibrosis indexes of patients with chronic hepatitis B（CHB）. Methods We randomly selected 84 cases of patients treated with CHB from February 2012 to March 2014 in our hospital，all the selected patients were randomly divided into 2 groups: the treatment group（GSH combined ETV treatment，n＝43） and the control group （use ETV treatment，n＝41）. The serum liver fibrosis indexes were compared between two groups after treatment. The serum liver fibrosis indexes were compared between pre -and post- treatment in the treatment group．Results（1）After treatment， serum liver fibrosis indexes of the treatment group were significantly lower than those in control group （P < 0.05）， the difference was statistically significant.（2）In the control group， the serum liver fibrosis indexes of post-treatment were significantly lower than those pre-treatment's（P < 0.05）， the difference was statistically significant. Conclusion　The combination therapy of GSH and ETV can effectively reduce the serum levels of liver fibrosis indexes and delay the formation process of liver fibrosis.
- ［Key words］Chronic hepatitis B；GSH；ETV； Liver fibrosis indexes,

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