The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB

Zhou Ying

Article Contents

Article Navigation > Journal of Kunming Medical University > 2016 > 37(04):

Zhou Ying . The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB[J]. Journal of Kunming Medical University, 2016, 37(04).

Citation:

Zhou Ying . The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB[J]. Journal of Kunming Medical University, 2016, 37(04).

Zhou Ying . The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB[J]. Journal of Kunming Medical University, 2016, 37(04).

Citation:

Zhou Ying . The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB[J]. Journal of Kunming Medical University, 2016, 37(04).

PDF( 152 KB)

The Influence of GSH Combined ETV on Liver Fibrosis Indexes of Patients with CHB

Zhou Ying

(1)The First People’s Hospital of Xiantao Hubei,Xiantao Hubei 433000;2)Wuhan Institute of Technology,Wuhan Hubei 430032,China)

Abstract

Abstract

［Abstract］Objective To observe the influence of glutathion（GSH）combined entecavir（ETV） on the serum levels of liver fibrosis indexes of patients with chronic hepatitis B（CHB）. Methods We randomly selected 84 cases of patients treated with CHB from February 2012 to March 2014 in our hospital，all the selected patients were randomly divided into 2 groups: the treatment group（GSH combined ETV treatment，n＝43） and the control group （use ETV treatment，n＝41）. The serum liver fibrosis indexes were compared between two groups after treatment. The serum liver fibrosis indexes were compared between pre -and post- treatment in the treatment group．Results（1）After treatment， serum liver fibrosis indexes of the treatment group were significantly lower than those in control group （P < 0.05）， the difference was statistically significant.（2）In the control group， the serum liver fibrosis indexes of post-treatment were significantly lower than those pre-treatment's（P < 0.05）， the difference was statistically significant. Conclusion　The combination therapy of GSH and ETV can effectively reduce the serum levels of liver fibrosis indexes and delay the formation process of liver fibrosis.
- ［Key words］Chronic hepatitis B；GSH；ETV； Liver fibrosis indexes,

FullText(HTML)

References(0)

References

Relative Articles(20)

Relative Articles

[1]	Rui YIN, Guowei MA, Wenxi YUE, Haixia GU, Ying ZHOU, Jie CHEN. Efficacy of Nucleotide Analog Monotherapy and Combination Therapy with Interferon in Treating Chronic Hepatitis B. Journal of Kunming Medical University, 2024, 46(): 1-10.
[2]	Changyong WU, Rui WANG, Suli BAO, Ruijie LI, Huang SUN, Yujia YE, Fei XU, Yunzhu PENG. Effects of Exercise Rehabilitation on Cardiac Fibrosis and Function in Rats with Myocardial Infarction. Journal of Kunming Medical University, 2023, 44(10): 26-32. doi: 10.12259/j.issn.2095-610X.S20231004
[3]	Di HE, Peng CHEN, Feng LIU, Yang XU, Lei HAN, Wenjing DING. Progress in Etiology and Pathogenesis of Liver Fibrosis. Journal of Kunming Medical University, 2022, 43(11): 165-171. doi: 10.12259/j.issn.2095-610X.S20221122
[4]	Yong-jun LIU, Yin WANG, Mei YANG, E-gao YIN, Ting LI, Zhao-xing DONG. The Effect of Hydrogen-Regulated Autophagy on Pulmonary Fibrosis in Paraquat Poisoned Rats. Journal of Kunming Medical University, 2021, 42(9): 1-6. doi: 10.12259/j.issn.2095-610X.S20210918
[5]	Li LIU, Jun-yi LI, Chun-yun LIU, Ying-rong DU, Jian-peng GAO, Hui-ming LI, Wei-kun LI, Yan-wei QI, Hui WANG. Effect of Tenofovir Combined with Ganshuang Granule on Hemodynamics of Portal Vein System in Hepatitis B Liver Cirrhosis. Journal of Kunming Medical University, 2021, 42(11): 134-139. doi: 10.12259/j.issn.2095-610X.S20211125
[6]	Qin XIE, Yan-ping LIANG, Yin ZHANG, Zeng-hui XU, Li-ying YOU. Efficacy of Multiple Non-invasive Diagnostic Models in the Diagnosis of Hepatic Fibrosis in Patients with Chronic Liver Diseases. Journal of Kunming Medical University, 2021, 42(7): 115-120. doi: 10.12259/j.issn.2095-610X.S20210719
[7]	Na PI, Qin HE, Yan ZHONG, Xuan JIN, Zhen-dong ZHU, Xuan ZHANG. Effect of Gentiana Rigescens Franch on Expression of NF - κ B and CTGF in Lung Tissue of Mice with Pulmonary Fibrosis. Journal of Kunming Medical University, 2021, 42(4): 8-12. doi: 10.12259/j.issn.2095-610X.S20210402
[8]	Li Ting , Deng Shu Hao , Liu Yong Jun , Dong Zhao Xing . . Journal of Kunming Medical University, 2019, 40(08): 1-5.
[9]	Cao Yu Ting , Wang Qi Xian , Yang Ping . . Journal of Kunming Medical University, 2019, 40(04): 136-139.
[10]	Liu Hu Jun , Gao Li Ping . . Journal of Kunming Medical University, 2017, 38(03): 94-97.
[11]	Wang Ying Xia . Anti-fibrotic Effect of Kudancao Tablets on Bleomycin-induced Pulmonary Fibrosis in Rats. Journal of Kunming Medical University,
[12]	Li Ye . Expression and Effects of New Fibrotic Gene SFTPA2 in Unilateral Ureteral Obstruction Rats with Renal Interstitial Fibrosis. Journal of Kunming Medical University,
[13]	Dong Zhao Xing . . Journal of Kunming Medical University,
[14]	He Min . . Journal of Kunming Medical University,
[15]	Yang Jing . . Journal of Kunming Medical University,
[16]	Zeng Jin . . Journal of Kunming Medical University,
[17]	Zhou Shu . . Journal of Kunming Medical University,
[18]	An Zhi . . Journal of Kunming Medical University,
[19]	Song Hua . . Journal of Kunming Medical University,
[20]	Zhang Ji Zhou . Effect of Exogenous Carbon Monoxide on Gaseous Signaling Molecules in Hippocampus of Rats with Cerebral Ischemic-Reperfusion Injury. Journal of Kunming Medical University,