A Comparative Study of the Clinical Value of ECLIA and ELISA in the Diagnosis of Syphilis

［Abstract］Objective　To compare the clinical value of ECLIA and ELISA in the diagnosis of syphilis. Methods　Serum samples were collected from 183 patients with syphilis in our hospital，and 861 patients with non syphilis. ELISA method and ECLIA method were used to detect the antibody of syphilis antibody. Differences in sensitivity，specificity and accuracy were compared and analyzed by two methods. Results　The sensitivities of methods measured by ECLIA and ELISA were 100% and 99.45%， respectively. The specificity was 99.88% and 100%， respectively. There was no significant difference between ECLIA and ELISA（P＞0.05）. The sensitivity in ECLIA method is higher than that in ELISA method. Conclusions　ECLIA method is a sensitive， specific and accurate method for the detection of syphilis antibody，which has the advantages of simple operation， fast detection speed， good result and repeatability.