Clinical Characteristic of 34 Patients with Extranodal Nasal Type NK/T-Cell Lymphoma

Nie Bo

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Nie Bo . Clinical Characteristic of 34 Patients with Extranodal Nasal Type NK/T-Cell Lymphoma[J]. Journal of Kunming Medical University, 2016, 37(06).

Citation:

Nie Bo . Clinical Characteristic of 34 Patients with Extranodal Nasal Type NK/T-Cell Lymphoma[J]. Journal of Kunming Medical University, 2016, 37(06).

Nie Bo . Clinical Characteristic of 34 Patients with Extranodal Nasal Type NK/T-Cell Lymphoma[J]. Journal of Kunming Medical University, 2016, 37(06).

Citation:

Nie Bo . Clinical Characteristic of 34 Patients with Extranodal Nasal Type NK/T-Cell Lymphoma[J]. Journal of Kunming Medical University, 2016, 37(06).

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Clinical Characteristic of 34 Patients with Extranodal Nasal Type NK/T-Cell Lymphoma

Nie Bo

(Dept. of Hematology,The 1st Affiliated Hospital of Kunming Medical University Hematopathy Research Center of Yunnan Province,Kunming Yunnan 650032,China)

Abstract

Abstract

［Abstract］Objective　Analysis of clinical features and treatment of nasal type NK/T cell lymphoma, to improve the understanding of this special type of lymphoma．Method　The clinical data of 34 patients with nasal type NK/T cell lymphoma confirmed by pathology were retrospectively analyzed．Result　In 31 cases，26 cases were EB virus（EBV）infection positive，recent Treatment Effectiveness in the positive group was significantly lower than the negative group（38.46% vs. 87.50%；P＜0.05）. Follow up showed until October 2015, 19 of 34 patients died. Among them, 17 cases died of disease relapse or progression, 2 cases died of other diseases. 15 patients survived (11 of them were disease-free) and the median overall survival time was 37 months. The 2 year overall survival was related to clinical stage, B symptoms, EBV infection（the P values were 0.017/0.001，0.005，and 0.039 respectively)．Conclusion　EBV infection is associated with patient's treatment response in NK/T-Cell Lymphoma; and the prognosis is associated with clinical features such as clinical stage, B symptom，and EBV infection.
- ［Key words］Extranodal NK/T-Cell Lymphoma；Lymphoma；Staging；Treatment；Prognosis,

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