Clinical Characteristic of 34 Patients with Extranodal Nasal Type NK/T-Cell Lymphoma

［Abstract］Objective　Analysis of clinical features and treatment of nasal type NK/T cell lymphoma, to improve the understanding of this special type of lymphoma．Method　The clinical data of 34 patients with nasal type NK/T cell lymphoma confirmed by pathology were retrospectively analyzed．Result　In 31 cases，26 cases were EB virus（EBV）infection positive，recent Treatment Effectiveness in the positive group was significantly lower than the negative group（38.46% vs. 87.50%；P＜0.05）. Follow up showed until October 2015, 19 of 34 patients died. Among them, 17 cases died of disease relapse or progression, 2 cases died of other diseases. 15 patients survived (11 of them were disease-free) and the median overall survival time was 37 months. The 2 year overall survival was related to clinical stage, B symptoms, EBV infection（the P values were 0.017/0.001，0.005，and 0.039 respectively)．Conclusion　EBV infection is associated with patient's treatment response in NK/T-Cell Lymphoma; and the prognosis is associated with clinical features such as clinical stage, B symptom，and EBV infection.