Researche Progress in Establishment of Human Sebocytes Culture Models in Vitro and Its Applications in Clinic

Deng Zhen Jun; Zhang Li; Wu Wen Juan; He Li; Lv Le Chun

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Deng Zhen Jun , Zhang Li , Wu Wen Juan , He Li , Lv Le Chun . Researche Progress in Establishment of Human Sebocytes Culture Models in Vitro and Its Applications in Clinic[J]. Journal of Kunming Medical University, 2017, 38(01): 129-132.

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Deng Zhen Jun , Zhang Li , Wu Wen Juan , He Li , Lv Le Chun . Researche Progress in Establishment of Human Sebocytes Culture Models in Vitro and Its Applications in Clinic[J]. Journal of Kunming Medical University, 2017, 38(01): 129-132.

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Researche Progress in Establishment of Human Sebocytes Culture Models in Vitro and Its Applications in Clinic

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基金：国家自然科学基金资助项目 (81360234, 81560502); 云南省院省校科技合作专项基金资助项目 (2014IB008);

Received Date: 2016-10-14

Abstract

Abstract

Sebaceous gland is the vital appendix organ of skin, and the abnormal of its function is associated with the development of acne and other diseases involving the sebaceous gland.The establishment of human sebocytes culture models in vitro provides a good platform for the study of sebaceous gland function and related diseases.At present, there has been already developed the immortalized human sebaceous gland cell lines, like SZ95 sebocytes, SEB-1 sebocytes, Seb-E6E7 sebocytes, which become unique tools for research on functions and activity regulations of sebaceous gland, as well the pathogenesis and therapy of acne and other sebaceous gland-associated disorders.This article summarizes the foundation of human sebocytes culture models in vitro and the development of immortalized human sebaceous gland cell lines, also discusses its applications in clinic researches.
- Human Sebocytes,
- Vitro cell Culture,
- Acne

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References(29)

References

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