Relationship between Soluble Cytokine Receptors, Matrix Metalloproteinases and Pancreatic Cancer

Yang Ke; Dan Zu Jian; Zhou Qiong Hua; Wang Jun Feng

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Yang Ke , Dan Zu Jian , Zhou Qiong Hua , Wang Jun Feng . Relationship between Soluble Cytokine Receptors, Matrix Metalloproteinases and Pancreatic Cancer[J]. Journal of Kunming Medical University, 2017, 38(01): 99-102.

Citation:

Yang Ke , Dan Zu Jian , Zhou Qiong Hua , Wang Jun Feng . Relationship between Soluble Cytokine Receptors, Matrix Metalloproteinases and Pancreatic Cancer[J]. Journal of Kunming Medical University, 2017, 38(01): 99-102.

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Relationship between Soluble Cytokine Receptors, Matrix Metalloproteinases and Pancreatic Cancer

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基金：云南省卫生科技计划基金资助项目 (2010NS005);

Received Date: 2016-10-10

Abstract

Abstract

Objective To investigate the relationship between soluble cytokine receptors, matrix metalloproteinases and pancreatic cancer.Methods Fifty-nine patients with pancreatic cancer in our hospital from April 2014 to May 2016 were selected in the observation group, 59 healthy subjects were selected in the control group, then the serum soluble cytokine receptors and matrix metalloproteinases levels of control group and observation group were detected and compared, and the detection results of observation group with different Hemrick stages and pathological classifications were compared, then the relationship between soluble cytokine receptors, matrix metalloproteinases and pancreatic cancer were analyzed by the Logistic analysis.Results The serum soluble cytokine receptors and matrix metalloproteinases levels of observation group were all higher than the levels of control group, the detection levels of patients with higher Hemrick stages were all higher than the levels of patients with lower Hemrick stages, all P <0.05, while the detection levels of patients with different pathological classifications had no obvious differences, all P >0.05, the Logistic analysis showed that the soluble cytokine receptors and matrix metalloproteinases all had close relationship to the pancreatic cancer.Conclusion Thesoluble cytokine receptors and matrix metalloproteinases of patients with pancreatic cancer show higher expression state, and have a indication value for the Hemrick staging, these indexes have high monitoring value for pancreatic cancer.
- Soluble cytokine receptors,
- Matrix metalloproteinases,
- Pancreatic cancer

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References(10)

References

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