Effect of Gangliosides in Improving the Cerebral Blood Flow and Nerve Function Indexes of Newborns with Hypoxic Ischemic Encephalopathy

Li Ke Xing; Zou Yi; Zhang Li Jiao

Volume 38 Issue 04

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Li Ke Xing , Zou Yi , Zhang Li Jiao . Effect of Gangliosides in Improving the Cerebral Blood Flow and Nerve Function Indexes of Newborns with Hypoxic Ischemic Encephalopathy[J]. Journal of Kunming Medical University, 2017, 38(04): 113-116.

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Effect of Gangliosides in Improving the Cerebral Blood Flow and Nerve Function Indexes of Newborns with Hypoxic Ischemic Encephalopathy

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基金：四川省攀枝花市科技计划项目[2010CY-S-1(12)];

Received Date: 2016-12-06

Abstract

Abstract

Objective To study and analyze the effect of gangliosides in improving the cerebral blood flow and nerve function indexes of newborns with hypoxic ischemic encephalopathy. Methods Sixty-eight newborns with hypoxic ischemic encephalopathy in our hospital from March 2015 to October 2016 were selected as the study object,and they were randomly divided into control group( 34 cases) and observation group(34 cases). The control group was treated with conventional treatment of hypoxic ischemic encephalopathy, the observation group was treated with conventional treatment and gangliosides,then the middle cerebral artery and anterior cerebral artery cerebral blood flow parameters and serum nerve function indexes of two groups before the treatment and at first and second week after the treatment were detected, and the detection results of two groups at different time points were respectively compared. Results The middle cerebral artery and anterior cerebral artery cerebral blood flow parameters and serum nerve function indexes of two groups before the treatment were compared,all P>0.05,and the middle cerebral artery and anterior cerebral artery cerebral blood flow parameters of observation group at first and second week after the treatment were all higher than the results of control group,and serum nerve function indexes were all lower than the results of control group,all P<0.05. Conclusion The gangliosides can significantly improve the cerebral blood flow and nerve function indexes of newborns with hypoxic ischemic encephalopathy, so the application value of gangliosides in these newborns is higher.
- Gangliosides,
- Newborns with hypoxic ischemic encephalopathy,
- Cerebral blood flow,
- Nerve function

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[1]赵亚娟,李婕,陈会宁.单唾液四己糖酸神经节苷脂钠治疗新生儿缺氧缺血性脑病疗效观察[J].吉林医学,2014,35(27):5999-6000.
[2]胡永艳,樊黎明.单唾液酸四己糖神经节苷脂钠注射液对新生儿缺氧缺血性脑病神经行为的影响[J].中国妇幼保健,2013,28(5):781-783.
[3]王昌乐.复方丹参注射液联合单唾液酸四己糖神经节苷脂钠治疗新生儿缺氧缺血性脑病疗效观察[J].现代中西医结合杂志,2016,25(20):2257-2259.
[4]周武.神经节苷脂治疗新生儿缺氧缺血性脑病的临床效果[J].中外医学研究,2014,12(8):22-23.
[5]	[5]VERA JOANNA BURTON,GWENDOLYN GERNER,ELIZABETH CRISTOFALO,et al.A pilot cohort study of cerebral autoregulation and 2-year neurodevelopmental outcomes in neonates with hypoxic-ischemic encephalopathy who received therapeutic hypothermia[J].BMC neurology,2015,15(5):209.
[6]	[6]YING TANG,QING SHANG.Neonatal hypoxic ischemic encephalopathy treated with acupuncture combined with acupoint injection:A randomized controlled trial[J].Chinese acupuncture&moxibustion,2015,35(7):641-645.
[7]翟粉竹.神经节苷脂联合早期综合治疗对新生儿缺氧缺血性脑病的疗效分析[J].中国实用神经疾病杂志,2015,18(14):125-126.
[8]宋天琦,付金玲,王策.神经节苷脂对新生儿缺氧缺血性脑病的疗效及其对血管内皮生长因子、神经肽Y水平的影响[J].中国妇幼保健,2015,30(25):4327-4328.
[9]张杰.单唾液酸四己糖神经节苷脂钠治疗新生儿缺氧缺血性脑病的临床疗效[J].医学理论与实践,2016,29(10):1352-1353.
[10]张英利.神经节苷脂联合胞二磷胆碱治疗新生儿缺氧缺血性脑病的疗效[J].中国实用神经疾病杂志,2013,16(23):93-94.
[11]邵波,胡文辉.单唾液酸四己糖神经节苷脂治疗新生儿缺氧缺血性脑病的疗效及安全性[J].中国现代医生,2014,52(8):57-59.
[12]李花,韦红.神经节苷脂治疗新生儿缺氧缺血性脑病的Meta分析[J].四川医学,2014,35(6):705-708.
[13]吴敏,方国秀.单唾液酸四己糖神经节苷脂钠注射液治疗新生儿缺氧缺血性脑病48例疗效观察[J].航空航天医学杂志,2013,24(7):838-839.
[14]	[14]TURKAN KOYUNCUOGLU,MESUT TURKYILMAZ,BULENT GOREN,et al.Uridine protects against hypoxic-ischemic brain injury by reducing histone deacetylase activity in neonatal rats[J].Restorative neurology and neuroscience,2015,33(5):777-784.

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