Volume 38 Issue 04
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Article Navigation >  Journal of Kunming Medical University  > 2017  >  38(04): 113-116
Xilan WU, Hong SHEN, Susheng SHI, Zhihui ZHANG, Lei GUO, Fang WANG. The Expression of PD-L1, BRAFV600E, CD68 Protein and the Significance of Tumor Infiltrating Lymphocytes in the Diagnosis of Malignant Melanoma[J]. Journal of Kunming Medical University, 2022, 43(9): 13-18. doi: 10.12259/j.issn.2095-610X.S20220923
Citation: Li Ke Xing , Zou Yi , Zhang Li Jiao . Effect of Gangliosides in Improving the Cerebral Blood Flow and Nerve Function Indexes of Newborns with Hypoxic Ischemic Encephalopathy[J]. Journal of Kunming Medical University, 2017, 38(04): 113-116.
shu

Effect of Gangliosides in Improving the Cerebral Blood Flow and Nerve Function Indexes of Newborns with Hypoxic Ischemic Encephalopathy

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基金： 四川省攀枝花市科技计划项目[2010CY-S-1(12)];

  • Received Date: 2016-12-06
    Abstract
  • Objective To study and analyze the effect of gangliosides in improving the cerebral blood flow and nerve function indexes of newborns with hypoxic ischemic encephalopathy. Methods Sixty-eight newborns with hypoxic ischemic encephalopathy in our hospital from March 2015 to October 2016 were selected as the study object,and they were randomly divided into control group( 34 cases) and observation group(34 cases). The control group was treated with conventional treatment of hypoxic ischemic encephalopathy, the observation group was treated with conventional treatment and gangliosides,then the middle cerebral artery and anterior cerebral artery cerebral blood flow parameters and serum nerve function indexes of two groups before the treatment and at first and second week after the treatment were detected, and the detection results of two groups at different time points were respectively compared. Results The middle cerebral artery and anterior cerebral artery cerebral blood flow parameters and serum nerve function indexes of two groups before the treatment were compared,all P>0.05,and the middle cerebral artery and anterior cerebral artery cerebral blood flow parameters of observation group at first and second week after the treatment were all higher than the results of control group,and serum nerve function indexes were all lower than the results of control group,all P<0.05. Conclusion The gangliosides can significantly improve the cerebral blood flow and nerve function indexes of newborns with hypoxic ischemic encephalopathy, so the application value of gangliosides in these newborns is higher.
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