Zhang Xue Qin , Xu Xiao Lin . Clinical Effect of Lansoprazole on Patients with Gastroesophageal Reflux and the Esophageal Dynamics[J]. Journal of Kunming Medical University, 2017, 38(04): 76-79.
Citation: Zhang Xue Qin , Xu Xiao Lin . Clinical Effect of Lansoprazole on Patients with Gastroesophageal Reflux and the Esophageal Dynamics[J]. Journal of Kunming Medical University, 2017, 38(04): 76-79.

Clinical Effect of Lansoprazole on Patients with Gastroesophageal Reflux and the Esophageal Dynamics

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基金: 云南省教育厅科学研究基金资助项目(2016ZZX207);

  • Received Date: 2017-02-13
  • Objective To observe the clinical effect of lansoprazole on the patients with gastroesophageal reflux and the influence on the esophageal dynamics. Methods Seventy-six patients with gastroesophageal reflux in our hospital from October 2015 to August 2016 were set as the study object,and 76 patients were randomly divided into control group(omeprazole group) and observation group(lansoprazole group),38 cases in each group,then the total effective rates,symptoms and signs score and esophageal dynamics indexes of patients in two groups before and after the treatment were respectively analyzed. Results The total effective rate of observation group was significantly higher than the rate of control group(P<0.05),the symptom and sign score and esophageal dynamics indexes of two groups before the treatment had no significantly differences(P>0.05),while the symptom and sign score and esophageal dynamics indexes of observation group after the treatment were all better than those of control group(P<0.05).Conclusion The clinical effect of lansoprazole in the patients with gastroesophageal reflux is better,and it can significantly improve the symptoms and signs and esophageal dynamics state,so its clinical application value is higher.
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