Ultrasonic Blood Flow Index Combined with Serum β-HCG in Mornitoring the Function of Placenta during Pregnancy

Huang Yan Ling; Lu Yong Ping; Ta Lin Kun; Xu Fei; Zhang Qiong

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Article Navigation > Journal of Kunming Medical University > 2017 > 38(06): 102-107

Huang Yan Ling , Lu Yong Ping , Ta Lin Kun , Xu Fei , Zhang Qiong . Ultrasonic Blood Flow Index Combined with Serum β-HCG in Mornitoring the Function of Placenta during Pregnancy[J]. Journal of Kunming Medical University, 2017, 38(06): 102-107.

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Huang Yan Ling , Lu Yong Ping , Ta Lin Kun , Xu Fei , Zhang Qiong . Ultrasonic Blood Flow Index Combined with Serum β-HCG in Mornitoring the Function of Placenta during Pregnancy[J]. Journal of Kunming Medical University, 2017, 38(06): 102-107.

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Ultrasonic Blood Flow Index Combined with Serum β-HCG in Mornitoring the Function of Placenta during Pregnancy

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基金：云南省应用基础研究基金资助项目 (2013FZ192);

Received Date: 2017-04-05

Abstract

Abstract

Objective To monitor placental function by using the ultrasonic blood flow index and serumβ-HCG.Me thods From May 2012 to December 2015 in our hospital, 1053 cases of prenatal puerperas were given placenta vascularization index (VI) , blood flow index (FI) and vascularization-blood flow index (VFI) measurement by GE E8 three-dimensional ultrasound at the same time, received β-HCG levels test by using the method of chemiluminescence. Postpartum neonatal body length, body weight and vital signs comprehensive score (Apgar score) were also recorded.Re s ults There were 131 cases with serum freeβ-HCGMo M≥2.5, 123 cases with neonatal weight < 2 500 g, 8 cases with normal weight; 542 cases with 2.0 <β-HCGMo M < 2.5, 4 cases with neonatal weight < 2500 g, 438 cases with normal weight; 425 cases with 1.5 <β-HCG Mo M<2.0, normal weight newborn; 59 cases with β-HCG Mo Mvalues <1.5, normal birth weight. The incidence of intrauterine retardation was 93.8% in puerperas with β-HCGMo M≥2.5, 0.7% in puerperas with 2.0<β-HCGMo M < 2.0, and 0% in puerperas with 1.5<β-HCGMo M < 2.0 and β-HCGMo M < 1.5. The incidence of intrauterine retardation in the group of pregnant women with serum free β-HCGMo M≥2.5 was significantly greater than the control group (P < 0.05) . The placental villi vascular tree of 1053 cases was reconstructed by 3 d power doppler technology, and the primary, secondary and tertiary villi rate of artery in 125 cases in the study group was100%, 73%, 38%, in 6 cases in the study group was 100%, 86% and 73% respectively, and in the control group, the primary, secondary and tertiary villi rate of artery was 100%, 100%, 85%, which were significantly higher than study group (P < 0.05) . Conclus ions When 2.5 > serum free β-HCGMo M of pregnant women > 2.0, the newborn may be associated with intrauterine retardation. Pregnant women serum freeβ-HCGMo M≥2.5, there is obviously increase in the incidence of neonatal intrauterine retardation. For those withintrauterine retardation, the placenta secondary and tertiary villi artery diameter is small, the number of artery decreases significantly. Three-dimensional power doppler blood flow index of VI, FI and VFI are significantly lower than normal. Serum free β-HCGMoM of pregnant women can predict the placenta function, villi vascular artery hierarchical display rate and the three-dimensional power doppler blood flow index can qualitatively and quantitatively determine the placental function. Placenta in mid gestation will be injured because of ischemia and anoxia, and the placental function can be recovered after placental vascular remodeling.
- Ultrasound indicator of blood flow,
- β-HCG,
- Placental insufficiency

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References(19)

References

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