Dang Yong , Duan Zhao . Staging Diagnosis of Endometrial Cancer by CT plus MRI and the Postoperative Level of VEGF-C[J]. Journal of Kunming Medical University, 2017, 38(06): 124-129.
Citation: Dang Yong , Duan Zhao . Staging Diagnosis of Endometrial Cancer by CT plus MRI and the Postoperative Level of VEGF-C[J]. Journal of Kunming Medical University, 2017, 38(06): 124-129.

Staging Diagnosis of Endometrial Cancer by CT plus MRI and the Postoperative Level of VEGF-C

Funds:

基金: 陕西省自然科学基金资助项目 (2013JM4012);

  • Received Date: 2017-03-10
  • Objective To explore the clinical application value of CT plus MRI in the staging diagnosis of endometrial cancer, and to evaluate the malignancy of cancer according to the postoperative level of VEGF-C.Me thods A total of 70 pathologically conformed endometrial cancercases were randomly selected. All patients underwent CT, MRI, and CT plus MRI examinations. Based on the staging confirmed by surgery, the accuracy rates of diagnosis of CT, MRI, and CT plus MRI were compared. The level of postoperative VGEF-C was observed to determine the malignancy of the cancer.Re s ults The accuracy rate of diagnosis of CT, MRI, and CT plus MRI before surgery was 59.4%, 65.7% and 92.1%, respectively. The rate of CT plus MRI was significantly higher than the rate of the other two examinations (P<0.05) . In addition, There was significant difference in the level of VEGF-C between endometrial cancers of differentstages. A positive correlation was observed between preoperative staging determined by CT plus MRI examination and the level of VEGF-C. Conclus ion CT plus MRI examination can produce high accuracy rate of staging diagnosis, which is positively correlated with the postoperative level of VEGF-C. Therefore, CT plus MRI examinationcan predict the malignancy of endometrial cancer, which is helpful for the clinical assessment and prognosis of endometrial cancer.
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