Changes in Composition of Lymphocytes in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Dai Bai Zhang; Ren Chao Feng; Zheng Qin Ling; Yang Yan Xia; Li Mei Hua

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Article Navigation > Journal of Kunming Medical University > 2017 > 38(06): 64-67

Dai Bai Zhang , Ren Chao Feng , Zheng Qin Ling , Yang Yan Xia , Li Mei Hua . Changes in Composition of Lymphocytes in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease[J]. Journal of Kunming Medical University, 2017, 38(06): 64-67.

Citation:

Dai Bai Zhang , Ren Chao Feng , Zheng Qin Ling , Yang Yan Xia , Li Mei Hua . Changes in Composition of Lymphocytes in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease[J]. Journal of Kunming Medical University, 2017, 38(06): 64-67.

Citation:

Dai Bai Zhang , Ren Chao Feng , Zheng Qin Ling , Yang Yan Xia , Li Mei Hua . Changes in Composition of Lymphocytes in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease[J]. Journal of Kunming Medical University, 2017, 38(06): 64-67.

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Changes in Composition of Lymphocytes in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Funds:

基金：云南省应用基础研究计划基金资助项目 (2013ZF223);

Received Date: 2017-02-21

Abstract

Abstract

Objective To study the changes in the composition of main lymphocytes in peripheral blood of patients with AECOPD (acute exacerbation of chronic obstructive pulmonary disease) . Me thods From January1 th, 2014 to 31 th December, total 789 admitted patients with AECOPD received immunologic function test. Their age ranged from 45 to 96 years old (76.33 ±9.56) . Mean ±SD was used in statistics and groups difference was analyzed by one way analysis of variance. Re s ults The data of 789 samples showed that CD3+ T lymphocyte subpopulation mean value was 60.07 ±13.11, which was lower than normal parameter. There was significant differences among different age groups (F3.410, P0.009) .According to statistics of different age groups, mean value of CD3+ T lymphocyte subpopulation was lower than normal parameter in patients with age ≥60y. The mean value changes of other lymphocyte subpopulation were in normal range. Conclus ions There is lower immunology function in patients with senile AECOPD, and the value of CD3+ T lymphocyte is significant difference among different age groups.
- Chronic obstructive pulmonary,
- Acute exacerbation,
- Lymphocyte

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References(15)

References

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