Influence of Dexmedetomidine on the Oxygenation and Cardio-pulmonary Function of Elderly Patients with Surgery

Song Shi Qin

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Song Shi Qin . Influence of Dexmedetomidine on the Oxygenation and Cardio-pulmonary Function of Elderly Patients with Surgery[J]. Journal of Kunming Medical University, 2017, 38(07): 122-125.

Citation:

Song Shi Qin . Influence of Dexmedetomidine on the Oxygenation and Cardio-pulmonary Function of Elderly Patients with Surgery[J]. Journal of Kunming Medical University, 2017, 38(07): 122-125.

Song Shi Qin . Influence of Dexmedetomidine on the Oxygenation and Cardio-pulmonary Function of Elderly Patients with Surgery[J]. Journal of Kunming Medical University, 2017, 38(07): 122-125.

Citation:

Song Shi Qin . Influence of Dexmedetomidine on the Oxygenation and Cardio-pulmonary Function of Elderly Patients with Surgery[J]. Journal of Kunming Medical University, 2017, 38(07): 122-125.

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Influence of Dexmedetomidine on the Oxygenation and Cardio-pulmonary Function of Elderly Patients with Surgery

Song Shi Qin

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基金：攀枝花市应用技术研究与开发基金资助项目[ (2012CY-S-22 (10) ];

Received Date: 2017-04-13

Abstract

Abstract

Objective To study and observe the oxygenation and cardio-pulmonary function of elderly patients with surgery after using dexmedetomidine. Methods A total of 82 elderly patients with surgery in the second People's Hospital of Panzhihua City from March 2015 to November 2016 were chosen and randomly divided into control group (conventional intervention group, 41 cases) and observation group (conventional intervention and dexmedetomidine group, 41 cases) . The oxygenation and cardio-pulmonary function indexes of the two groups at different time before and after the surgery were compared. Results There was no significant difference in oxygenation and cardio-pulmonary function indexes of the two groups before the surgery (P >0.05) while the oxygenation function and cardio-pulmonary function indexes of the observation group at 6 h, 12 h and 24 h after the surgery were significant better than those of the control group (P<0.05) . There were significant differences in the detection results after the surgery between the two groups. Conclusion Dexmedetomidine is good for the oxygenation and cardio-pulmonary function of elderly patients with surgery and it can improve the physical condition of the elderly patients with surgery.
- Dexmedetomidine,
- Elderly patients with surgery,
- Oxygenation function,
- Cardio-pulmonary function

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References(16)

References

[1]古粤峰, 杨丽, 朱冠楠.右美托咪定联合舒芬太尼用于老年高血压患者人工关节置换术后镇痛研究[J].北方药学, 2016, 13 (3) :70-71.
[2]贾宝森, 汪东昱, 王爱国, 等.右美托咪定对老年患者围术期脑氧饱和度和认知功能的影响[J].北京医学, 2016, 38 (3) :197-200.
[3]梁荣丰, 庄上英, 杨凤泉.右美托咪定联合达克罗宁胶浆对老年肾功能不全患者PCNL手术围插管与拔管期循环状况的影响[J].广东医学, 2016, 37 (12) :1782-1785.
[4]韩晓东, 林峥, 徐建伟, 等.右美托咪定复合全身麻醉对老年患者围术期的影响及感染预防[J].中华医院感染学杂志, 2013, 23 (24) :5997-5598.
[5]吉林, 王曙, 蔡国森, 等.右美托咪定复合罗哌卡因硬膜外麻醉在老年患者骨科手术的应用[J].国际麻醉学与复苏杂志, 2015, 36 (12) :1071-1074.
[6]孟海兵, 来伟, 帅君, 等.右美托咪定对老年患者全麻术后认知功能及炎症因子的影响[J].实用医学杂志, 2014, 30 (14) :2300-2301.
[7]李晓瑜, 吴国荣, 郑晋伟, 等.静脉输注右美托咪定辅助腰麻对老年患者髋关节置换术后镇痛的影响[J].浙江医学, 2016, 38 (16) :1362-1364.
[8]金鑫, 金超, 周艳瑾.右美托咪定对老年患者髋关节置换术后认知功能障碍及围术期T淋巴细胞亚群的影响[J].中国药房, 2016, 27 (2) :242-245.
[9]	[9]PARK S H, SHIN Y D, YU H J, et al.Comparison of two dosing schedules of intravenous dexmedetomidine in elderly patients during spinal anesthesia[J].Korean J Anesthesiol, 2014, 66 (5) :371-376.
[10]	[10]SINGH G D, KINJAVDEKAR P, AMARPAL, et al.Clinicophysiological and haemodynamic effects of fentanyl with xylazine, medetomidine and dexmedetomidine in isoflurane-anaesthetised water buffaloes (Bubalus bubalis) [J].J S Afr Vet Assoc, 2013, 84 (1) :1-11.
[11]李晓兰, 申海芳, 何军霞, 等.右美托咪定复合曲马多超前镇痛在老年腹部手术患者中的应用[J].临床合理用药杂志, 2015, 8 (19) :49-51.
[12]王睿, 任泽彬, 李国福, 等.围手术期老年患者应用右美托咪定有效性和安全性的Meta分析[J].药物不良反应杂志, 2014, 16 (4) :213-218.
[13]	[13]NASR D A, ABDELHAMID H M.The efficacy of caudal dexmedetomidine on stress response and postoperative pain in pediatric cardiac surgery[J].Ann Card Anaesth, 2013, 16 (2) :109-114.
[14]朱珠, 李玮伟.右美托咪定联合乌司他丁对体外循环手术所致心肺功能损伤的保护作用[J].海南医学院学报, 2016, 22 (21) :2566-2569.
[15]胡序凯, 郑晋伟, 陈骏萍, 等.右美托咪定对单肺通气时缺氧性肺血管收缩及氧合的影响[J].现代实用医学, 2014, 26 (2) :127-129.
[16]汪兵.联合使用右美托咪定对异丙酚-芬太尼平衡麻醉患者单肺通气状态下氧合功能的影响分析[J].当代医学, 2016, 22 (36) :38-39.

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