Effects of Alcohol on Hematological Indexes of Tupaia Belangeri Chinensis

Li Jin Tao; Ma Yi; Zhang Yu Wen; Tang Ying; Wang Qiong Xian; Zheng Hong

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Article Navigation > Journal of Kunming Medical University > 2017 > 38(07): 33-36

Li Jin Tao , Ma Yi , Zhang Yu Wen , Tang Ying , Wang Qiong Xian , Zheng Hong . Effects of Alcohol on Hematological Indexes of Tupaia Belangeri Chinensis[J]. Journal of Kunming Medical University, 2017, 38(07): 33-36.

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Li Jin Tao , Ma Yi , Zhang Yu Wen , Tang Ying , Wang Qiong Xian , Zheng Hong . Effects of Alcohol on Hematological Indexes of Tupaia Belangeri Chinensis[J]. Journal of Kunming Medical University, 2017, 38(07): 33-36.

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Effects of Alcohol on Hematological Indexes of Tupaia Belangeri Chinensis

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基金：国家自然科学基金资助项目 (81460647); 云南省科技厅-昆明医科大学应用基础研究联合专项基金资助 (2014FB033, 2012FB022) ;云南省科技厅-昆明医科大学应用基础研究联合专项资金青年博士项目 (2016); 云南省科技厅应用基础研究计划资助项目 (2012FB155);

Received Date: 2017-04-09

Abstract

Abstract

Objective To investigate the effect of alcohol on hematological indexes of Tupaia belangeri chinensis.Methods A total of 40 Tupaia belangeri chinensis, half male and half female, were randomly divided into alcohol group and control group. Tree shrews in alcohol group were given star Erguotou with alcohol content of 56% by gavage, with the dosage of 0.38 mL per 100 g while those in control group were given distilled water by gavage with the same dosage. After 90 days of gavage, 0.5 mL blood from the heart were taken 12 hours after fasting.EDTA-K2 was used and mini TEK-II automatic hematology analyzer was applied to measure the indexes of hematology, and the results were analyzed with SPSS software. Platelet count (PLT) , white blood cell (WBC) , the absolute value of lymphocyte (LY#) , Results The absolute value of intermediate cells (Mid#) and plateletcrit (PCT) in alcohol group were significantly higher than those in the control group (P <0.05) . In alcohol group, white blood cells (WBC) , lymphocyte absolute value (LY#) , the absolute value of intermediate cells (Mid#) of male tree shrews were significantly lower than those of female tree shrews (P <0.05) .Conclusions Alcohol can cause changes in tupaia belangeri chinensis hematological indexes, and the changes of female tree shrews are more significant.
- Alcohol,
- Tupaia belangeri chinensis,
- Hematology index

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References(14)

References

[1]	[1]FRANK WIENS, ANNET TE ZITZMANN, MARC-ANDRE LACHANCE, et al.Chronic intake of fermented floral nectar by wild tree shrews[J].PANS, 2008, 105 (30) :10426-10431.
[2]李璐依霏, 周立君.酒精性心肌病发病机制的研究进展[J].医学综述, 2015, 21 (4) :598-599.
[3]王夏珍, 张薇, 郭月宁, 等.酒精性肺疾病的临床研究及进展[J].现代生物医学进展, 2016, 16 (2) :393-396.
[4]韩桂玲, 杨海英.酒精的代谢与饮酒对人体的影响[J].山西医药杂志, 2012, 41 (22) :1150-1151.
[5]高潇雪, 刘立新.酒精性肝病流行病学及发病机制研究进展[J].中华消化病与影像杂志 (电子版) , 2016, 6 (2) :62-65.
[6]丁宁, 程勇前, 卿松, 等.大鼠急性酒精性肝损伤肝细胞凋亡及其发病机制研究[J].广西医学, 2013, 35 (11) :1502-1504.
[7]王思为, 夏道宗, 方月娟, 等.葛根复合胶囊对小鼠酒精性肝损伤的保护作用研究[J].云南中医学院学报, 2015, 38 (1) :1-4.
[8]李进涛, 郑红, 李文贵, 等.滇西亚种树鼩部分肝功能生化指标的测定及其分析[J].云南农业大学学报, 2014, 29 (1) :126-130.
[9]苏傲蕾, 秦银鸽, 郑禹, 等.树鼩的生物学特性研究概述[J].动物医学进展, 2014, 35 (10) :115-118.
[10]许凌, 范宇, 蒋学龙, 等.树鼩进化分类地位的分子证据[J].动物学研究, 2013, 34 (2) :70-76.
[11]徐林, 张云, 梁斌, 等.实验动物树鼩和人类疾病的树鼩模型研究概述[J].动物学研究, 2013, 34 (2) :59-69.
[12]侯治富.实验诊断学[M].北京:高等教育出版社, 2011:17-23.
[13]林振涛, 于红艳.酒的代谢与中毒[J].滨州医学院学报, 1999, 22 (3) :311-312.
[14]翟红梅, 肖颖, 肖霄, 等.酒在人体内的代谢及酒精中毒[J].石家庄学院学报, 2010, 12 (3) :27-29.

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