The Effect Study of Traumatic Occlusion on Rat Condylar Growth

Chen Jian Zhong; Xie Liang Kun; Wang Wei Qi; Dai Zi Chao; Yang Rong Qiang; Zhang Li; Jia Ling

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Chen Jian Zhong , Xie Liang Kun, Wang Wei Qi , Dai Zi Chao , Yang Rong Qiang , Zhang Li , Jia Ling . The Effect Study of Traumatic Occlusion on Rat Condylar Growth[J]. Journal of Kunming Medical University, 2017, 38(10): 1-5.

Citation:

Chen Jian Zhong , Xie Liang Kun, Wang Wei Qi , Dai Zi Chao , Yang Rong Qiang , Zhang Li , Jia Ling . The Effect Study of Traumatic Occlusion on Rat Condylar Growth[J]. Journal of Kunming Medical University, 2017, 38(10): 1-5.

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The Effect Study of Traumatic Occlusion on Rat Condylar Growth

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基金：国家自然科学基金资助项目 (81360136); 云南省内设机构项目 (2014NS291); 云南省科技厅-昆明医科大学应用基础研究基金资助项目 (2013FB176);

Received Date: 2017-05-14

Abstract

Abstract

Objective To investigate the effect of traumatic occlusion on the development of condylar.Methods Twenty-seven male SD rats were randomly divided into three groups, the traumatic side, the opposite side and blank control group. The rats of experiment group were perpormed to bond 1 mm steel-wire on left upper molar, the blank group were breeding normally. The condylar was dissected when the rats were 1, 3, 5 weeks after experiment. The histology section was used to observe the morphology of condylar. The immunohistochemical staining was used to examine the PCNA positive cell, TUNEL was chosen to detect the apoptotic cell.Results The histology section showed there was no significant difference between the three groups, the immunochemical stain and TUNEL showed there was no significant difference in the proliferated and apoptotic cells with 1, 5 week after experiment; the proliferated cell number decreased while the apoptotic cell increased on the traumatic side with 3 weeks after experiment, there was significant difference between three groups. Conclusion One side traumatic occlusion has no significant effect on condylar morphology, however has some influence on cell growth, it suggests that traumatic occlusion to some extent has no obvious effect on condylar growth.
- Traumatic occlusion,
- Condylar,
- Growth

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References(9)

References

[1]	[1]XIN-YUAN H U.Expression of MCP-1 and ICAM-1 in Periodontal Ligament in a Rat Model with Traumatic Occlusion[J].Progress in Modern Biomedicine 2015, 32 (4) :6234-6237.
[2]刘洪臣.咬合创伤对口颌系统及全身的影响及矫治[J].中华口腔医学杂志, 2002, 37 (4) :309-311.
[3]	[3]KAJIKAWA A, HIRABAYASHI S, HARII K.An experimental study on the growth of condylar cartilage, using a new vascularized mandible het-erotopic transplant model[J].J Oral Maxillofac Surg, 2003, 61 (2) :239-245.
[4]孟春秀, 刘迪, 赵晓, 等.咬合创伤导致大鼠睡眠时的脑电图变化[J].上海口腔医学, 2014, 23 (1) :26-29.
[5]贾静, 刘雪梅, 章捍东, 等.三叉神经脊束核尾侧亚核星形胶质细胞对咬合创伤的反应[J].口腔颌面修复学杂志, 2010, 11 (5) :257-259.
[6]李松, 金岩, 王惠芸, 等.细胞凋亡与bcl-2基因在颞下颌关节发育中的作用[J].华西口腔医学杂志, 1999, 17 (3) :205-217.
[7]	[7]SODEYAMA T, MAEDA T, TAKANO Y, et al.Responses of periodontal nerve terminals to experimentally induced occlusal trauma in rat molars:An immunohistochemical study using PGP 9.5 antibody[J].J Periodontal Res, 1996, 31 (4) :235-248.
[8]忻贤贞, 杨旭, 魏斌.SD大鼠咬合创伤模型的建立[J].上海口腔医学, 2016, 25 (3) :281-283.
[9]	[9]FU K, MA X, ZHANG Z.Ultrastructure of the synovial membrane and the articular cartilage in the temporomandibular joint of the rabbits with occlusal trauma[J].Zhonghua Kou Qiang Yi Xue Za Zhi, 1998, 33 (1) :18-20.

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