Adverse Reactions in Children with Acute Lymphoblastic Leukemia after Chemotherapy

Sun Jian Ming; Dong Fang

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Sun Jian Ming , Dong Fang . Adverse Reactions in Children with Acute Lymphoblastic Leukemia after Chemotherapy[J]. Journal of Kunming Medical University, 2017, 38(10): 107-111.

Citation:

Sun Jian Ming , Dong Fang . Adverse Reactions in Children with Acute Lymphoblastic Leukemia after Chemotherapy[J]. Journal of Kunming Medical University, 2017, 38(10): 107-111.

Sun Jian Ming , Dong Fang . Adverse Reactions in Children with Acute Lymphoblastic Leukemia after Chemotherapy[J]. Journal of Kunming Medical University, 2017, 38(10): 107-111.

Citation:

Sun Jian Ming , Dong Fang . Adverse Reactions in Children with Acute Lymphoblastic Leukemia after Chemotherapy[J]. Journal of Kunming Medical University, 2017, 38(10): 107-111.

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Adverse Reactions in Children with Acute Lymphoblastic Leukemia after Chemotherapy

Sun Jian Ming ¹,
Dong Fang ²

Funds:

基金：昆明市卫生科技人才培养项目暨“十百千”工程基金资助项目[ (SW (后备) 76) ];

Received Date: 2017-05-11

Abstract

Abstract

Objective To analyse the characteristics of adverse reactions in children with acute lymphoblastic leukemia after chemotherapy, and to implement individualized medication to avoid or reduce the occurrence of serious adrs. Methods The report on the adverse reactions in children with acute lymphoblastic leukemia after chemotherapy from 2015.2 to 2014.3 was collected, the patient gender, age, risk, drug and ADR involving organs or systems were analyzed. Results The adverse reactions in children with acute lymphoblastic leukemia after chemotherapy are involved mostly in the high-risk group of patients. L-asparaginase, vincristine and cytarabine were the top three drugs involved in adverse reactions. Blood system was the most common system involved in adverse reactions. Bone marrow suppression concurrent infection had significant difference between different risks and ages (P < 0.01) had no statistical difference between different genders (P > 0.05) . Conclusion Bone marrow suppression was the most common ADR in children with acute lymphoblastic leukemia after chemotherapy, and bone marrow suppression and concurrent infection have the greatest influence on the quality of life and the treatment effect of children.
- Children,
- ALL,
- Adverse reactions

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References(13)

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