Prevalence and Drug Resistance of Streptococcus Pneumoniae Infection in Children in Yuxi during from 2014 to 2016

Chen Jing Yi; Liao Fei; Feng Lei; Chu Cong Jia

Volume 38 Issue 11

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Chen Jing Yi , Liao Fei , Feng Lei , Chu Cong Jia . Prevalence and Drug Resistance of Streptococcus Pneumoniae Infection in Children in Yuxi during from 2014 to 2016[J]. Journal of Kunming Medical University, 2017, 38(11): 82-85.

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Prevalence and Drug Resistance of Streptococcus Pneumoniae Infection in Children in Yuxi during from 2014 to 2016

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基金：云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目 (2015FB084);

Received Date: 2017-05-11

Abstract

Abstract

Objective To learn the prevalence and drug resistance of Streptococcus pneumoniae (SPN) in children in Yuxi from 2014 to 2016, and to provide the basis for clinical rational drug use.Methods We made a retrospective analysis of 326 children with SPN, a strain collected from January 2014 to December 2016 in Yuxi city children's Hospital, and statistical analysis.The infection condition was analyzed in the recent three years, in different season and in children with different age and different gender.The antimicrobial susceptibility test was performed by VITEK2 bacterial identification and susceptibility system of France bio Merieux company, according to the CLSI criteria of drug sensitivity analysis results.Results Children's SPN infection of Yuxi increased year by year, mainly in infants under one year of age in the 326 strains of SPN (62.3%) , most of them were boys (63.2%) , from the seasonal distribution, winter (10-12 months) than the susceptible (50.9%) .SPN to vancomycin and cefepime, amoxicillin/clavulanate, linezolid.Telithromycin sensitive rate was 100%, to ceftriaxone, cefotaxime resistance rate increased, the resistant rate of penicillin decreased, The resistance rate of clindamycin, clarithromycin, erythromycin and Azithomycinwas was extremely high.Conclusions The prevalence of SPN infection in children in Yuxi increased obviously, and the incidence rate was higher in winter.The infants under one year old were more susceptible to infection and the majority were boys.amoxicillin/clavulanate, and three or four generation cephalosporins can be used as the preferred drug for the treatment of SPN infection;penicillin, clindamycin, clarithromycin, erythromycin and azithromycin can not be used for the treatment of SPN infection;to vancomycin resistant strains.It is suggested that local epidemiological data should be taken for rational use of the drug according to the results of drug sensitivity.
- Streptococcus pneumonia,
- Children,
- Epidemiology,
- Antibiotics,
- Drug resistance

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[1]	[1]PELLEGRINO P, CARNOVALE C, PERRONE V, et al.Epidemiological analysis on two decades of hospitalisations for meningitis in the United States[J].European Journal of Clinical microbiology infectious Diseases, 2014, 33 (9) :1519-1524.
[2]张泓, 李万华, 孔菁, 等.儿童肺炎链球菌血清型分布及其对抗菌药物的耐药性[J].中国感染与化疗杂志, 2011, 8 (4) :287-290.
[3]苏小燕, 温顺航, 林立, 等.儿童肺炎链球菌败血症的临床特点及药敏分析[J].中国当代儿科杂志, 2013, 15 (11) :995-999.
[4]	[4]ANON.Pneumococcal conjugate vaccine for childhood immunization-WHO position paper[J].Weekly Epidemiological Record, 2007, 82 (12) :93-104.
[5] 朱旭慧, 孙自镛, 刘彩林, 等.2000-2009年同济医院肺炎链球菌的耐药性分析[J].中华检验医学杂志, 2011, 34 (1) :46-49.
[6]	[6]Clinicaland Laboratory Standards Institute.Performance standards for antimicrobial susceptibility testing;Approved Standard-Eleventh Edition[S].M100-S23, CLSI, 2013.
[7]陈炯, 陈亚萍.宁波市儿童肺炎链球菌感染流行情况及耐药性分析[J].儿科药学杂志, 2016, 22 (8) :43-45.
[8]张书婉, 王敏江, 余建华, 等.儿童肺炎链球菌感染流行病学及耐药分析[J].海南医学, 2015, 26 (1) :93-95.
[9]	[9]WIERZBOWSKI A K, NICHOL K, LAING N, et al.Macrolide resistance mechanisms among Streptococcus pneumoniae isolated over 6 years of Canadian Respiratory Organism Susceptibility Study (CROSS) (1998-2004) [J].Journal of Antimicrobial Chemotherapy, 2007, 60 (4) :733-740.
[10]徐丽慧.王贤军.方美玉, 等.肺炎链球菌大环内酯药物耐药性及耐药基因erm、mef的检测[J].中华传染病杂志, 2010, 28 (3) :174-177.

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