The Advanced Progress on the Analgesic Mechanism of Oxytocin

Luo Ya Fan; Li Guo Ping; Chen Shao Chun; Han Yi

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Luo Ya Fan , Li Guo Ping , Chen Shao Chun , Han Yi . The Advanced Progress on the Analgesic Mechanism of Oxytocin[J]. Journal of Kunming Medical University, 2018, 39(01): 1-4.

Citation:

Luo Ya Fan , Li Guo Ping , Chen Shao Chun , Han Yi . The Advanced Progress on the Analgesic Mechanism of Oxytocin[J]. Journal of Kunming Medical University, 2018, 39(01): 1-4.

Luo Ya Fan , Li Guo Ping , Chen Shao Chun , Han Yi . The Advanced Progress on the Analgesic Mechanism of Oxytocin[J]. Journal of Kunming Medical University, 2018, 39(01): 1-4.

Citation:

Luo Ya Fan , Li Guo Ping , Chen Shao Chun , Han Yi . The Advanced Progress on the Analgesic Mechanism of Oxytocin[J]. Journal of Kunming Medical University, 2018, 39(01): 1-4.

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The Advanced Progress on the Analgesic Mechanism of Oxytocin

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作者简介：韩毅, 男, 49岁, 副教授, 硕士研究生导师.1993年毕业于昆明医学院临床医学专业, 现为昆明医科大学基础医学院副院长, 云南省生理科学会理事长、中国生理学会理事.专业方向为循环生理、神经生理;研究方向为心肌缺血的信号通路研究、痛觉调制及镇痛机制研究.主持云南省科技厅-昆明医科大学联合项目1项, 参与国家自然科学基金项目3项、云南省科技厅-昆明医科大学联合重点项目1项.近年来发表论文10余篇, 其中SCI收录论文7篇.E-mail:kmhanyi@163.com; 罗雅范 (1992~) , 女, 四川雅安市人, 在读硕士研究生, 主要从事镇痛机制研究工作.; 陈绍春.E-mail:shaochunchen@126.com;

基金：国家自然科学基金资助项目 (81260195, 81302362);

Received Date: 2017-09-12

Abstract

Abstract

Oxytocin (OT) is a 9-amino-peptide hormone synthesized mainly in the Paraventricular Nucleus (PVN) and Supraoptic Nucleus (SON) of mammals’hypothalamus.Small part of OT is synthesized in peripheral organs.In addition to promoting the lactation and uterine contraction, OT has many other physiological functions, such as analgesia.It has been proved that neuropeptide can exert analgesic effect.OT is indeed a neuropeptide secreted naturally by mammals.Sdudies have shown that OT plays an important role in relieving pain and can avoid problems like addiction and other side effects.However, its underlying mechanism of analgia is still unclear.Therefore, further study of the analgesic mechanism of oxytocin has a great theoretic significance and very broad clinical prosperities.
- Oxytocin,
- Analgesia,
- Mechanism

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References(23)

References

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