The Observation on the Effect of Q-Switching Nd:YAG Treatment in Pigmented Dermatoses and Influence for Melanin Metabolism

Ding Zu Lie; Chen Tao; Li Sheng Hua

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Ding Zu Lie , Chen Tao , Li Sheng Hua . The Observation on the Effect of Q-Switching Nd:YAG Treatment in Pigmented Dermatoses and Influence for Melanin Metabolism[J]. Journal of Kunming Medical University, 2018, 39(01): 104-108.

Citation:

Ding Zu Lie , Chen Tao , Li Sheng Hua . The Observation on the Effect of Q-Switching Nd:YAG Treatment in Pigmented Dermatoses and Influence for Melanin Metabolism[J]. Journal of Kunming Medical University, 2018, 39(01): 104-108.

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The Observation on the Effect of Q-Switching Nd:YAG Treatment in Pigmented Dermatoses and Influence for Melanin Metabolism

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基金：国家自然科学基金资助项目 (81172832);

Received Date: 2017-08-11

Abstract

Abstract

Objective To observe the effect of Q-Switching Nd:YAG treatment in pigmented dermatoses and its influence for melanin metabolism. Methods 114 patients with pigmented dermatoses in our hospital from October 2015 to August 2016 were selected as the study object, and were randomly divided into the control group (57 cases) and the observation group (57 cases) .The control group were treated with intense pulsed light therapy while the observation group were treated with Q-Switching Nd:YAG treatment on the treatment of control group.Then the total effective rates, recurrence rates, adverse reaction rates, skin lesion scores and serum melanin metabolism related indexes before and after the treatment of two groups were analyzed and compared. Results Clinically, the total effective rates of observation group were higher than those of control group (P<0.05) and the recurrence rate of observation group was lower than that of control group (P<0.05) .The adverse reaction rates of two groups were compared and the differences were not statistically significant ( P >0.05) .The skin lesion scores and serum melanin metabolism related indexes of two groups before the treatment were compared and the differences were not statistically significant (P>0.05) .The serum melanin metabolism related indexes of two groups after the treatment were all better than those of control group ( P <0.05) . Conclusion The clinical effect of Q-Switching Nd:YAG treatment in the patients with pigmented dermatoses is better, and it has the active influence for the melanin metabolism, so it has higher clinical value in the treatment of pigmented dermatoses.
- Q-Switching Nd,
- YAG treatment,
- Pigmented dermatoses,
- Clinical effect,
- Melanin metabolism

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References(17)

References

[1]李俞晓, 韩婷梅, 郭晓光, 等.大光斑低能量Q开关Nd:YAG激光联合化瘀祛斑胶囊治疗黄褐斑疗效观察[J].中国美容医学, 2015, 24 (16) :36-39.
[2]林辉, 文清, 张晶晶, 等.大光斑低能量Q开关Nd:YAG激光联合中药面膜治疗黄褐斑疗效观察[J].中国皮肤性病学杂志, 2016, 30 (9) :958-960.
[3]马少吟, 程军平, 王艳芳, 等.Q开关Nd:YAG激光联合谷胱甘肽、维生素C治疗黄褐斑疗效分析[J].国际皮肤性病学杂志, 2013, 39 (2) :83-85.
[4]杨菁, 张正中, 牟韵竹, 等.Q开关Nd:YAG激光治疗色素性皮肤病239例临床疗效观察[J].皮肤病与性病, 2013, 35 (5) :281-282.
[5]佘文莉, 黄海玲, 刘晖, 等.Q开关nd:YAG激光治疗皮肤色素性病变术前术中局部冰敷效果评估[J].广东医学, 2013, 34 (4) :648-649.
[6]	[6]KWON H H, OHN J, SUH D H, et al.A pilot study for triple combination therapy with a low-fluence 1064?nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl's Melanosis[J].J Dermatolog Treat, 2017, 28 (2) :155-159.
[7]施学清.血府逐瘀胶囊联合激光治疗黄褐斑的临床疗效及对黑素指数的影响[J].黑龙江医药, 2016, 29 (1) :107-108.
[8]应为红, 张理梅, 李嫦嫦.中药祛斑霜对黄褐斑豚鼠模型皮肤中SOD、MDA和黑素颗粒的影响[J].上海中医药杂志, 2017, 51 (1) :97-101.
[9]谢爱娣, 刘锦群, 陈晓梨.姜黄素治疗黄褐斑的疗效观察及其对黑素的影响[J].黑龙江医学, 2015, 39 (10) :1163-1164.
[10]	[10]VACHIRAMON V, PANMANEE W, TECHAPICHETVANICH T, et al.Comparison of Q-switched Nd:YAG laser and fractional carbon dioxide laser for the treatment of solar lentigines in Asians[J].Lasers Surg Med, 2016, 48 (4) :354-359.
[11]	[11]NOH T K, CHUNG B Y, YEO U C, et al.Q-switched660-nm versus 532-nm Nd:YAG laser for the treatment for facial lentigines in asian patients:A prospective, randomized, double-blinded, split-Face comparison pilot study[J].Dermatol Surg, 2015, 41 (12) :1389-1395.
[12]李娟, 颜敏, 张媛, 等.黄褐斑病因、发病机制及治疗进展[J].中国麻风皮肤病杂志, 2016, 32 (2) :123-126.
[13]张国栋, 黄恺飞, 黄亦琦.清斑胶囊对小鼠B16黑素细胞增值、酪氨酸酶活性及黑色素含量影响的研究[J].柳州医学, 2014, 27 (3) :125-12.
[14]马彦, 冯文莉, 杨静, 等.调Q开关翠绿宝石激光治疗282例色素性皮肤病临床分析[J].中国药物与临床, 2013, 13 (3) :301-304.
[15]刘丽琴, 杨晓红, 王金燕, 等.祛斑汤治疗气滞血瘀型黄褐斑疗效及对外周血中血管内皮生长因子的影响[J].中国中西医结合皮肤性病学杂志, 2015, 14 (6) :374-376.
[16]车启蕾, 付萌, 李承新.黄褐斑病因及发病机制的研究进展[J].国际皮肤性病学杂志, 2016, 42 (2) :82-83.
[17]黎颖诗, 杨海波, 黄艳, 等.强脉冲光联合Q开关Nd:YAG激光治疗雀斑的疗效观察[J].岭南皮肤性病科杂志, 2009, 16 (5) :299-301.

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