Zhou Xiao Nan , Song Xue Lan , Yang Yuan , Ma Chen Jing , He Fang Yan . Advances and Applications in Gene Silencing[J]. Journal of Kunming Medical University, 2018, 39(01): 131-135.
Citation: Zhou Xiao Nan , Song Xue Lan , Yang Yuan , Ma Chen Jing , He Fang Yan . Advances and Applications in Gene Silencing[J]. Journal of Kunming Medical University, 2018, 39(01): 131-135.

Advances and Applications in Gene Silencing

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基金: 国家自然科学基金资助项目 (81560664, 81660677);

  • Received Date: 2017-10-06
  • Gene silencing is a phenomenon in which the specific genes in organisms are not expressed or reduced for various reasons. It is an important mechanism to control gene expression by epigenetic control. At present, scientists intend to explore the treatment of difficult diseases through gene silencing technology, and the research has become a hot spot. With the rapid development of gene engineering, gene silencing technology has been replaced by new technologies. This paper aims to introduce the ribozyme technology, antisense oligonucleic acid technology, gene knockout, RNA interference technology and their applications in gene silencing technology.
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