Chemerin in Obstructive Sleep Apnea-hypopnea Patients' Pharyngeal Fat Deposition

Wu Hai Ying; Cao Shou Ming; Shi Bin; Bai Zhong; Li Yong Xia

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Wu Hai Ying , Cao Shou Ming , Shi Bin , Bai Zhong , Li Yong Xia . Chemerin in Obstructive Sleep Apnea-hypopnea Patients' Pharyngeal Fat Deposition[J]. Journal of Kunming Medical University, 2018, 39(01): 77-80.

Citation:

Wu Hai Ying , Cao Shou Ming , Shi Bin , Bai Zhong , Li Yong Xia . Chemerin in Obstructive Sleep Apnea-hypopnea Patients' Pharyngeal Fat Deposition[J]. Journal of Kunming Medical University, 2018, 39(01): 77-80.

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Chemerin in Obstructive Sleep Apnea-hypopnea Patients' Pharyngeal Fat Deposition

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基金：云南省卫计委内设机构研究项目 (2016NS290);

Received Date: 2017-09-01

Abstract

Abstract

Objective To analyze the effect of chemerin on the pharyngeal fat deposition by comparing the level of chemerin of fat tissue in pharynx between the patients with OSAHS and non-snorer. Methods OSAHS patients finished PSG and non-snoring patients with tonsillitis as controlled group were examined to observe their chemerin level of space veli palatine. Comparisons of the chemerin level and the indexes of MS were made to analyze the relationship between chemerin and MS. Results The level of chemerin of space veli palatine in OSAHS patients was higher than that of the control groups. And the level of chemerin within the OSAHS patients also had positive correlation with TG、HOMA-IR and uric acid. We also found that the TG, HDL-C, FINS, HOMA-IR and the uric acid had statistical differences (P <0.05) between the two groups. Conclusion The level of chemerin of OSAHS group is exceed the control group and positively related with indexes of MS. Chemerin may take part in the development of fat deposition in pharynx of OSAHS patients, which may be through MS pathway.
- Obstructive sleep apnea-hypopnea syndrome,
- Chemerin,
- Metabolic Syndrome

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References(14)

References

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