Chen Mo , Zhou Ze Ping . The Progress of IL-10 and Autoimmune Diseases[J]. Journal of Kunming Medical University, 2018, 39(02): 1-4.
Citation: Chen Mo , Zhou Ze Ping . The Progress of IL-10 and Autoimmune Diseases[J]. Journal of Kunming Medical University, 2018, 39(02): 1-4.

The Progress of IL-10 and Autoimmune Diseases

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作者简介: 陈墨 (1992~) , 男, 湖北黄石市人, 在读硕士研究生, 主要从事血液科临床工作.; 周泽平.E-mail:zhouzeping@outlook.com男, 43岁, 博士, 教授, 博士研究生导师.2007年毕业于中国协和医科大学.现为昆明医科大学第二附属医院血液科主任, 云南省中青年学术及技术带头人后备人才, 云南省高层次卫生技术人才学科带头人, 云南省省级临床重点专科负责人, 昆明医科大学创新团队负责人.中华医学会血液学分会止血与血栓学组委员、青年委员, 云南省血液学会副主任委员, 中国研究型医院学会生物治疗学专委会委员, 中国老年医学会血液学分会委员, 昆明医科大学第七届学术委员会委员等.主持国家自然科学基金3项, 省部级项目8项, 发表论文50篇, 其中SCI收录23篇.参编英文专著1部及中文专著5部.;

基金: 国家自然科学基金资助项目 (81560029); 云南省中青年学术及技术带头人后备人才基金资助项目 (2013HB088);

  • Received Date: 2017-11-19
  • Interleukin-10 (IL-10) , a single strand glycoprotein, is produced by both adaptive and innate immune cells. IL-10 specific receptor as a complex consists of two submits IL-10 R1 and IL-10 R2. IL-10 mainly plays biological functions via JAK-STAT signaling pathway. IL-10 is a crucial anti-inflammation cytokine taking part in immune regulation and having significant effect on autoimmune diseases. This paper reviews the relationships between IL-10 and autoimmune diseases according to research achievements in recent years.
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