A Study of Correlation between NDST3 Gene Polymorphism and Schizophrenia Among Han People in Yunnan

Jiang Hong Yan; Ran Liu Yi; Wu Gui Xia; Xu Xiu Feng; Yu Li

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Jiang Hong Yan , Ran Liu Yi , Wu Gui Xia , Xu Xiu Feng , Yu Li . A Study of Correlation between NDST3 Gene Polymorphism and Schizophrenia Among Han People in Yunnan[J]. Journal of Kunming Medical University, 2018, 39(02): 51-54.

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Jiang Hong Yan , Ran Liu Yi , Wu Gui Xia , Xu Xiu Feng , Yu Li . A Study of Correlation between NDST3 Gene Polymorphism and Schizophrenia Among Han People in Yunnan[J]. Journal of Kunming Medical University, 2018, 39(02): 51-54.

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A Study of Correlation between NDST3 Gene Polymorphism and Schizophrenia Among Han People in Yunnan

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基金：云南省教育厅科学研究基金资助项目 (2014C029Y);

Received Date: 2017-10-17

Abstract

Abstract

Objective To investigate the association between rs11098403 of the NDST3 gene and schizophrenia among Han People in Yunnan. Me thods A total of 364 Han patients with schizophrenia and 287 healthy Han people were enrolled in our study. SNa P shot was used to detect the genotype of rs11098403. Positive and Negative Symptoms scale (PANSS) was used to assess the symptoms of schizophrenia.Re s ults No differences were found in the genotype and allele distributions of rs11098403 among patients and the control group (P>0.05) .The allelic frequencies of rs11098403 showed no significant association with positive symptoms, negative symptoms or general symptoms (P>0.05) . Conclus ions Our study indicated that the association between NDST3 gene and schizophrenia might be specific to European population.
- Schizophrenia,
- NDST3,
- Polymorphism,
- rs11098403,
- Han Chinese,
- Positive and Negative Symptoms Scale

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References(12)

References

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