Investigation on the Secondary Epilepsy Occurrence of Patients with Cerebral Infarction and Its Risk Factors

Du Rong; Xu Bi Zhi

Article Contents

Article Navigation > Journal of Kunming Medical University > 2018 > 39(04): 100-103

Du Rong , Xu Bi Zhi . Investigation on the Secondary Epilepsy Occurrence of Patients with Cerebral Infarction and Its Risk Factors[J]. Journal of Kunming Medical University, 2018, 39(04): 100-103.

Citation:

Du Rong , Xu Bi Zhi . Investigation on the Secondary Epilepsy Occurrence of Patients with Cerebral Infarction and Its Risk Factors[J]. Journal of Kunming Medical University, 2018, 39(04): 100-103.

Du Rong , Xu Bi Zhi . Investigation on the Secondary Epilepsy Occurrence of Patients with Cerebral Infarction and Its Risk Factors[J]. Journal of Kunming Medical University, 2018, 39(04): 100-103.

Citation:

Du Rong , Xu Bi Zhi . Investigation on the Secondary Epilepsy Occurrence of Patients with Cerebral Infarction and Its Risk Factors[J]. Journal of Kunming Medical University, 2018, 39(04): 100-103.

PDF( 198 KB)

Investigation on the Secondary Epilepsy Occurrence of Patients with Cerebral Infarction and Its Risk Factors

Du Rong ,
Xu Bi Zhi

Funds:

基金：四川省卫生厅科研基金资助项目 (140041);

Received Date: 2017-01-05

Abstract

Abstract

Objective To observe the incidence of secondary epilepsy in patients with cerebral infarction and explore the risk factors of secondary epilepsy. Me thods Eighty-four patients with secondary epilepsy diagnosed as cerebral infarction from April 2016 to August 2017 in our hospital were selected as the observation group, and 84 patients of cerebral infarction without epilepsy in the same period were selected as the control group. Follow-up of secondary epileptic seizures, the general information of patients, basic diseases, hypertension grade, blood electrolytes, lesion location, diameter of lesion were recorded, and the risk factors of secondary epilepsy in cerebral infarction were screened, and the status of secondary epilepsy were analyzed. Re s ults (1) The types of epilepsy in secondary epilepsy: partial seizure in 69 cases, complete attack in 15 cases; onset time: early onset in 60 cases, late in 24 cases. (2) There was no significant difference between the two groups in general information, underlying disease, lesion diameter and grade ofhypertension (P>0.05) . The differences statistically significento significance in the consist of lesion location and lesion specific location and blood electrolyte levels (P <0.05) .Unconditional multivariate logistic regression analysis showed thoao infarction involving the cortex, temporal lobe, and serum chloride value was correlated with the occurrence of secondary epilepsy (P<0.05) . (3) MultivariateLogistic regression analysis showed tthat infaretion involving the cortex (OR = 3.10, P = 0.004, 95% CI =1.52-7.41) , locating in the temporal lobe, (OR = 2.98, P = 0.012, 95% CI = 1.32-7.35) and serum chlorine (OR = 1.25, P = 0.017, 95% CI = 1.00-1.38) were the risk factors for secondary epilepsy in cerebral infarction.Conclusions Partial and early onset of seizures are the most common in cerebral infarction secondary epilepsy.Infarction involving the cortex, locating in the temporal lobe and serum chlorine are the risk factors for secondary epilepsy in patients with cerebral infarction. Necessary measures should be taken to intervene at high risk of secondary epilepsy and to improve the clinical quality of life of patients.
- Secondary epilepsy,
- Cerebral infarction,
- High risk factors,
- Involving in the cortex,
- Serum chloride

FullText(HTML)

References(15)

References

[1]王建茹.100例中老年继发性癫痫的发作类型及病因[J].中风与神经疾病杂志, 2011, 21 (1) :82-83.
[2]刘国政.缺血性脑血管病的研究进展[J].实用心脑肺血管病杂志, 2013, 21 (8) :5-6.
[3]	[3]GILAD R.Management of seizures following a stroke:What are the options[J].Druge Aging, 2012, 29 (7) :533-538.
[4]丁巧丽.脑卒中后癫痫的临床分析96例[J].中国社区医师, 2013, 15 (9) :29-30.
[5]王彦廷.脑卒中继发性癫痫30例临床分析[J].中国实用神经疾病杂志, 2014, 17 (7) :99-100.
[6] 慕容洋洋, 江山, 苏宁.脑卒中继发性癫痫的临床治疗与进展性研究[J].中华内科杂志, 2015, 44 (3) :163-166.
[7]陈文军, 荣阳, 荣根满.急性脑梗死后早期继发性癫痫的临床分析[J].中外医学, 2011, 9 (29) :52-53.
[8]邓颉, 张月华, 刘晓燕.发作和癫痫分类框架相关术语和概念修订--国际抗癫痫联盟分类和术语委员会报告, 2005-2009年[J].中国实用儿科杂志, 2011, 26 (7) :505-511.
[9]张振强, 宋军营, 贾亚泉.缺血性脑血管疾病研究进展[J].河南大学学报 (医学版) , 2013, 31 (4) :312-317.
[10]沈惠芬, 徐玲芬, 赵红艳.老年脑卒中患者早发性癫痫的护理[J].解放军护理杂志, 2011, 28 (5) :60-61.
[11]郭宁, 叶春林, 毕春辉.2001年国际抗癫痫联盟关于癫痫分类建议的临床应用讨论[J].武警后勤学院学报 (医学版) , 2013, 22 (10) :893-895.
[12]吴立文, 邓施萍, 彭炳蔚.癫痫及癫痫综合症国际分类 (1989年) 的临床应用分析[J].中华神经科杂志, 2005, 38 (6) :370-372.
[13]	[13]HSU C J, WENG W C, PENG S S, et al.Early-onset seizures are correlated with late-onset seizures in children with arterial ischemic stroke[J].Stroke, 2014, 45 (4) :1161-1163.
[14]	[14]PROCACCIANTI G, ZANIBONI A, RONDELLI F, et al.Seizures in acute stroke:Incidence, risk factors and prognosis[J].Neuroepidemiology, 2012, 39 (1) :45-50.
[15]程海军.脑卒中后继发性癫痫82例临床分析[J].中西医结合心脑血管病杂志, 2014, 12 (4) :453-455.

Relative Articles(20)

Relative Articles

[1]	Yi YANG, Yong-bo ZHANG. Value of Neutrophil to Lymphocyte Ratio and Derived Neutrophil to Lymphocyte Ratio in Prediction of Hemorrhagic Transformation In Acute Ischemic Stroke with Large-artery Atherosclerosis. Journal of Kunming Medical University, 2021, 42(11): 33-37. doi: 10.12259/j.issn.2095-610X.S20211106
[2]	Ran Xiao Ming , Song Rui Peng , Sun Dan . . Journal of Kunming Medical University, 2020, 41(05): 85-90.
[3]	Li Min , Li Yu Huan , Xiong Guang Run , Zheng Yong Qiang . . Journal of Kunming Medical University, 2019, 40(09): 101-105.
[4]	Yang Juan , Zhao Xiao Hui , Li Jin Shi , Liu Hui Qin , Wang Ling Ling , Ren Hai Bing , Wang Si Si , Yan Jing , Sui Hai Jing . . Journal of Kunming Medical University, 2019, 40(04): 101-106.
[5]	Wei Qing , Zhang Rui , Liu Jun Mei , Dai Xiao Rong . . Journal of Kunming Medical University, 2017, 38(02): 104-108.
[6]	Zhang Xi Li , Meng Wen , Li Qing Ye , Wang Guo Liang , Li Yan Lin , Zhang Xiao Mei . Prevention of Postherpetic Neuralgia by Nerve Block and Analysis of Risk Factors. Journal of Kunming Medical University, 2017, 38(09): 96-99.
[7]	Yang Bi Qing , Wang Xun . Significance of Serum Total Bilirubin Level in Cerebral Emergencies. Journal of Kunming Medical University, 2017, 38(09): 66-70.
[8]	Xu Bi Zhi , Du Rong , Wu Xiao Cui . Influence of Optimized Nursing Process on the Clinical Effect and Quality of Life of Patients with Cerebral Infarction Received Intravenous Thrombolysis. Journal of Kunming Medical University, 2016, 37(12): 144-147.
[9]	Rao Yan . . Journal of Kunming Medical University,
[10]	Li Peng Xiang . . Journal of Kunming Medical University,
[11]	Shen Yue Ling . . Journal of Kunming Medical University,
[12]	Huang Wei . . Journal of Kunming Medical University,
[13]	You Li Na . . Journal of Kunming Medical University,
[14]	You Li Na . . Journal of Kunming Medical University,
[15]	Ling Kai Jian . . Journal of Kunming Medical University,
[16]	Nie Zhi . . Journal of Kunming Medical University,
[17]	. The Clinical Study on Treatment of Acute Cerebral Infarction with Hydrochloric Fasudil. Journal of Kunming Medical University,
[18]	Li Qiu Yuan . . Journal of Kunming Medical University,
[19]	Li Ye Hong . . Journal of Kunming Medical University,
[20]	Li Fu Ping . . Journal of Kunming Medical University,