Comparison of Different Dosages of Rocuronium on Abdominal Wound Closure

Liao Fei; Qu Qi Cai; Huang Qing Qing; Tao Jian Ping; Si Yong Yu

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Article Navigation > Journal of Kunming Medical University > 2018 > 39(05): 56-60

Liao Fei , Qu Qi Cai , Huang Qing Qing , Tao Jian Ping , Si Yong Yu . Comparison of Different Dosages of Rocuronium on Abdominal Wound Closure[J]. Journal of Kunming Medical University, 2018, 39(05): 56-60.

Citation:

Liao Fei , Qu Qi Cai , Huang Qing Qing , Tao Jian Ping , Si Yong Yu . Comparison of Different Dosages of Rocuronium on Abdominal Wound Closure[J]. Journal of Kunming Medical University, 2018, 39(05): 56-60.

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Comparison of Different Dosages of Rocuronium on Abdominal Wound Closure

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基金：云南省卫生系统学科带头人基金资助项目 (D-201213);

Received Date: 2018-03-09

Abstract

Abstract

Objective To evaluate the effects of different dosages of rocuronium on abdominal wound closure under general anesthesia.Me thods Ninety ASA class I or II patients scheduled for elective abdominal surgery under general anesthesia were randomized into three groups with 30 cases each.Each group received rocuronium 1 time of ED95 (0.3 mg/kg) , 0.5 time of ED95 (0.15 mg/kg) , 0.2 time of ED95 (0.06 mg/kg) respectively when closing the abdominal wall.TOF recovered to 25%, 75%, 90%, time of eye-opening on command, time of head-lift for more than 5 seconds, extubation time, the rate of upper airways obstruction after extubation and the satisfaction score for the muscle relaxation to general surgeons were recorded.Re s ults TOF values had no significantly different among the three groups before abdominal wound closure (P>0.05) .Compared with group A and group B, time of TOF in group C was significangtly increased after administration of rocuronium (P<0.05) .Time of TOF recovery to 25%, 75%, 90% in group C were significangtly decreased (P<0.01) .Compared with group A and group B, time of eye-opening on command, head-lift for more than 5 seconds and extubation time were significantly shorter in group C.There were 8, 4, 0 patients undwent upper airways obstruction among each group respectively after extubation (P<0.05) .The satisfaction score for muscle relaxation among three groups had no significant difference.Conclus ion An additional administration of 0.2 time of ED95 (0.06 mg/kg) rocuronium before abdominal wound closure in abdominal surgery can achieve satisfactory muscle relaxation for surgeons.
- Rocuronium,
- Abdominal wound closure,
- Train-of-four stimulation,
- Residual paralysis

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References(20)

References

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