Research Progress of Dendrobium in the Treatment and Prevention of Diabetes

Shi Bao Sheng; Shao Ya Ting; Chen Li Jun; Zhang Liang; Pu Dong; Wen Xiao Ling; Chen Ya Ping; Li Yu Peng

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Shi Bao Sheng , Shao Ya Ting , Chen Li Jun , Zhang Liang , Pu Dong , Wen Xiao Ling , Chen Ya Ping , Li Yu Peng . Research Progress of Dendrobium in the Treatment and Prevention of Diabetes[J]. Journal of Kunming Medical University, 2018, 39(07): 129-132.

Citation:

Shi Bao Sheng , Shao Ya Ting , Chen Li Jun , Zhang Liang , Pu Dong , Wen Xiao Ling , Chen Ya Ping , Li Yu Peng . Research Progress of Dendrobium in the Treatment and Prevention of Diabetes[J]. Journal of Kunming Medical University, 2018, 39(07): 129-132.

Citation:

Shi Bao Sheng , Shao Ya Ting , Chen Li Jun , Zhang Liang , Pu Dong , Wen Xiao Ling , Chen Ya Ping , Li Yu Peng . Research Progress of Dendrobium in the Treatment and Prevention of Diabetes[J]. Journal of Kunming Medical University, 2018, 39(07): 129-132.

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Research Progress of Dendrobium in the Treatment and Prevention of Diabetes

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基金：国家自然科学基金资助项目 (21202066); 云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目[2017FE468 (-025) , 2017FE467 (-020) ]; 云南省教育厅科学研究基金资助项目 (2015Y151, 2016ZDX050);

Received Date: 2017-10-19

Abstract

Abstract

With the expansion of consumer markets and groups in last decades, Dendrobium species as traditional Chinese medicine herbs have been becoming increasingly popular for its outstanding pharmacological and health effects. This review will detail the important functions of Dendrobium compound preparation, Dendrobium candidum, Dendrobium nobile Lindl, Dendrobium chrysotoxum Lindl, Dendrobium huoshanense, Dendrobium moniliforme and Dendrobium denneanum in the term of prevention and cure about diabetes.
- Dendrobium,
- Diabetes,
- Research progress

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References(43)

References

[1]施红, 杨奇红, 余文珍, 等.石斛合剂预先给药对糖尿病大鼠的防治作用[J].康复学报, 2004, 14 (1) :20-22.
[2]施红, 林雅, 余文珍, 等.石斛合剂改善模型大鼠胰岛素抵抗的实验研究[J].康复学报, 2004, 14 (6) :24-27.
[3]施红, 杨奇红, 张捷平, 等.石斛合剂对高脂高糖加STZ造模大鼠的作用及机制探讨[J].中药药理与临床, 2002, 18 (3) :22-23.
[4]	[4]SHI H, JIN G Q, GAO Y L.The regulation of Dendrobium Compound (DC) on m RNA and protein expression of Bax, Bcl-2 genes associated with apoptosis in aged diabetic rats’pancreas[J].Chinese Journal of Gerontology, 2006, 26 (1) :57-60.
[5]郑晓玲, 高长花, 施红.石斛合剂影响DM大鼠脂肪因子的实验研究[J].福建中医药, 2013, 44 (2) :51-64.
[6]林雅, 余文珍, 郑燕芳, 等.石斛合剂对糖尿病大鼠模型血糖血脂代谢的影响[J].康复学报, 2012, 22 (3) :22-23.
[7]辛金钟, 王麒又, 陈丽娟, 等.石斛合剂改善2型糖尿病胰岛素抵抗的临床研究[J].中国现代医生, 2010, 48 (3) :58-59.
[8]严晓丹, 王林, 郑雪花, 等.石斛合剂对2型糖尿病模型大鼠脂肪组织内脂素基因表达的影响[J].山西医科大学学报, 2015, 46 (8) :734-736.
[9]王林, 严晓丹, 王晓宁, 等.石斛合剂对2型糖尿病模型大鼠脂肪细胞因子基因表达的影响[J].康复学报, 2014, 24 (3) :8-10.
[10]	[10]LI T M, DENG M Z.Effect of Dendrobium mixture on hypoglycemic and the apoptosis of islet in rats with type 2 diabetic mellitus[J].Journal of Chinese Medicinal Materials, 2012, 35 (35) :765-769.
[11] 周勇, 施红.石斛合剂通过AMPK通路调节糖尿病大鼠糖脂代谢的分子机制[J].母婴世界, 2016, (14) :25-29.
[12]秦崇涛, 张捷平, 刘如玉, 等.石斛合剂对2型糖尿病大鼠肝脏蛋白表达的影响[J].山东医药, 2016, 56 (30) :39-42.
[13]郑雪花, 钱长晖, 何才姑, 等.石斛合剂对糖尿病大鼠肾脏自噬表达的影响[J].康复学报, 2010, 20 (1) :27-28.
[14]李长征, 余文珍, 蒋艺燕, 等.石斛合剂对糖尿病大鼠肾脏的保护作用[J].康复学报, 2012, 22 (3) :18-21.
[15]高尤亮, 施红, 杨秀珍, 等.石斛合剂对糖尿病模型大鼠胰岛细胞凋亡及凋亡相关基因Bax、Bcl-2 m RNA表达的影响[J].南昌大学学报 (医学版) , 2012, 52 (6) :6-9.
[16]王晓宁, 郑燕芳, 余文珍, 等.石斛合剂等降糖中药方对衰老糖尿病大鼠胰腺PCNA、NF-κBp65的影响[J].世界中医药, 2016, 11 (2) :296-300.
[17]刘赟, 施红, 林心君, 等.石斛合剂对老年糖尿病大鼠GCK、GLUT-2的影响[J].山西中医学院学报, 2014, 15 (4) :27-29.
[18]刘赟, 施红, 林心君, 等.石斛合剂调控老年糖尿病大鼠GLP-1的研究[J].天津中医药大学学报, 2015, 34 (6) :346-348.
[19]余文珍, 施红, 郑燕芳.石斛合剂对衰老糖尿病大鼠血清GLP-1水平的影响[J].海南医学院学报, 2006, 12 (3) :196-199.
[20]高长花, 余文珍, 施红, 等.石斛合剂对糖尿病模型大鼠胰高血糖素样肽-1的影响[J].中医临床研究, 2013, 5 (23) :5-7.
[21]张捷平, 郑晓玲, 洪佳祝, 等.复方石斛合剂治疗2型糖尿病90例[J].福建中医药大学学报, 2011, 21 (5) :6-8.
[22]	[22]WU H S, XU J H, CHEN L Z, et al.Studies on anti-hyperglycemic effect and its mechanism of Dendrobium candidum[J].China journal of Chinese materia medica, 2004, 29 (2) :160-163.
[23]	[23]ZHANG B B, LIU W H, Li J F, et al.Effects of polysaccharides from Dendrobium officinale on expression of Bax and Bcl-2 in vascular endothelial cells induced by high sugar[J].Chinese Pharmacological Bulletin, 2015, 31 (1) :64-70.
[24]陈泳荪, 刘文洪.铁皮石斛多糖提取工艺及其对高糖诱导血管内皮细胞NF-κB表达干预的研究[J].山西中医学院学报, 2011, 12 (2) :27-31.
[25]	[25]CHANG H, HOSPITAL Q P.Effects of Dendrobium candidum on phosphorylation expression of JNK and AKT protein in rats with type 2 diabetes mellitus[J].Environmental&Molecular Mutagenesis, 2008, 49 (5) :360-367.
[26]宓文佳, 陈素红, 吕圭源, 等.铁皮石斛根提取物对2型糖尿病模型小鼠的降糖作用研究[J].中药药理与临床, 2015, 31 (1) :125-129.
[27]李雅嘉, 王华, 李强翔.铁皮石斛多糖对高糖状态下视网膜Müller细胞活力及凋亡的调控[J].中国老年学杂志, 2014, 34 (23) :6683-6685.
[28]李静文, 李国文, 秦瑜, 等.铁皮石斛多糖对糖尿病大鼠视网膜炎症因子表达干预的研究[J].中国中医眼科杂志, 2016, 26 (1) :7-11.
[29]蔡伟, 张宏桂, 刘朋朋, 等.金钗石斛水提物对链脲霉素高血糖小鼠的降血糖作用研究[J].中医药学报, 2013, 41 (4) :15-17.
[30]刘庆春.金钗石斛对糖尿病大鼠肝组织胰岛素受体基因表达的影响[J].中医临床研究, 2017, 9 (13) :44-45.
[31]刘庆春.金钗石斛对糖尿病大鼠肝脏TNF-α表达的影响[J].中医临床研究, 2017, 9 (10) :9-10.
[32]刘庆春.金钗石斛对糖尿病大鼠肝组织NF-κB表达的影响[J].中医临床研究, 2017, 9 (11) :23-24.
[33]	[33]JIN H, YANG G Z, XIAO-QIONG L I, et al.Effects of Dendrobium nobile extract on RAGE expression of renal tissue in diabetic rat model[J].Chinese Journal of Biochemical Pharmaceutics, 2011, 32 (3) :209-212.
[34]黄琦, 廖鑫, 吴芹, 等.金钗石斛生物总碱对糖尿病大鼠血糖及肝脏脂肪变性的影响[J].中国新药与临床杂志, 2013, 32 (6) :490-493.
[35]黄琦, 廖鑫, 吴芹, 等.金钗石斛生物总碱对糖尿病大鼠血糖及肝脏组织IRS-2 m RNA, IGF-1 m RNA表达的影响[J].中国实验方剂学杂志, 2014, 20 (19) :155-158.
[36]陶凤, 金徽, 杨贵忠, 等.金钗石斛水提物对糖尿病大鼠肾组织非酶糖基化及氧化的影响[J].山东大学学报 (医学版) , 2012, 50 (10) :11-22.
[37]林达秋, 黄宇, 林永东, 等.金钗石斛治疗气阴两虚型2型糖尿病作用的临床研究[J].中医临床研究, 2016, 8 (9) :48-52.
[38]魏小勇, 龙艳.金钗石斛生物碱抗糖性白内障作用及蛋白质组学效应的实验研究[J].天然产物研究与开发, 2008, 20 (4) :617-621.
[39]余增洋, 陆宾, 季莉莉, 等.鼓槌石斛改善糖尿病性视网膜病活性及其机制[J].国际药学研究杂志, 2016, 43 (2) :301-306.
[40]余增洋, 盛雨辰, 周玲玉, 等.鼓槌石斛对小鼠非增殖性糖尿病视网膜病变的改善作用及其机制研究[J].中草药, 2016, 47 (11) :1908-1913.
[41]李秀芳, 邓媛元, 潘利华, 等.霍山石斛多糖对糖尿病性白内障大鼠眼球晶状体组织抗氧化作用的研究[J].中成药, 2012, 34 (3) :418-421.
[42]	[42]LUO A, ZE C, SHAORONG G E, et al.Effect of Dendrobium denneanum polysaccharide reducing blood glucose in vivo[J].Chinese Journal of Applied&Environmental Biology, 2006, 12 (3) :334-337.
[43]陈云龙, 何国庆, 张铭, 等.细茎石斛多糖的降血糖活性作用[J].浙江大学学报 (理学版) , 2003, 30 (6) :693-696.

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