Analysis on the Detection of Carbapenem-Resistant Klebsiella Pneumonia in a Hospital in Recent 5 Years

Yang Mei Jun; Pan Xing; Ye Ji Ming

Volume 39 Issue 07

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Yang Mei Jun , Pan Xing , Ye Ji Ming . Analysis on the Detection of Carbapenem-Resistant Klebsiella Pneumonia in a Hospital in Recent 5 Years[J]. Journal of Kunming Medical University, 2018, 39(07): 76-79.

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Yang Mei Jun , Pan Xing , Ye Ji Ming . Analysis on the Detection of Carbapenem-Resistant Klebsiella Pneumonia in a Hospital in Recent 5 Years[J]. Journal of Kunming Medical University, 2018, 39(07): 76-79.

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Analysis on the Detection of Carbapenem-Resistant Klebsiella Pneumonia in a Hospital in Recent 5 Years

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基金：云南省教育厅科学研究基金资助项目 (2013C247);

Received Date: 2018-03-10

Abstract

Abstract

Objective To understand the detection of clinically isolated carbapenem-resistant Klebsiella pneumonia (CRKP) , and propose a strategy for drug treatment, so as to provide evidence for treatment and prevention of CRKP nosocomial infections.Me thods The isolated CRKP specimens from inpatients from 2013 to2017 were collected in a local hospital. Detection rate and sources of specimens were analyzed. Re s ults Totally2, 237 strains of Klebsiella pneumonia were detected, and 76 (accounting for 3.40%) were CRKP strains. The detection rate of CRKP from 2013 to 2017 showed an upward trend gradually, and the difference was statistically significant (P <0.01) . A positive correlation was observed between the detection rate of CRKP and DDDS of carbapenems, and the difference was statistically significant (P<0.05) . The main infection of CRKP occurred in respiratory tract and urinary tract, and detection of CRKP was mainly from ICU, neurosurgery and geriatrics departments. Conclus ion CRKP infection increase year by year, which should receive sufficient clinical and infection control attention. Therapy of CRKP infection is mainly based on the combined tigecycline or polymyxin.
- Carbapenem-resistant Klebsiella pneumonia,
- Detection,
- Treatment strategy

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