Update of Treatment for Lowering Serum Urate

Hu Xin Yu; Zhang Nan; Dong Xian Xiang; Duan Wei Gang; Yun Yu

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Hu Xin Yu , Zhang Nan , Dong Xian Xiang , Duan Wei Gang , Yun Yu . Update of Treatment for Lowering Serum Urate[J]. Journal of Kunming Medical University, 2019, 40(03): 131-135.

Citation:

Hu Xin Yu , Zhang Nan , Dong Xian Xiang , Duan Wei Gang , Yun Yu . Update of Treatment for Lowering Serum Urate[J]. Journal of Kunming Medical University, 2019, 40(03): 131-135.

Hu Xin Yu , Zhang Nan , Dong Xian Xiang , Duan Wei Gang , Yun Yu . Update of Treatment for Lowering Serum Urate[J]. Journal of Kunming Medical University, 2019, 40(03): 131-135.

Citation:

Hu Xin Yu , Zhang Nan , Dong Xian Xiang , Duan Wei Gang , Yun Yu . Update of Treatment for Lowering Serum Urate[J]. Journal of Kunming Medical University, 2019, 40(03): 131-135.

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Update of Treatment for Lowering Serum Urate

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基金：国家自然科学基金资助项目 (81860162); 云南省教育厅科学研究基金资助项目 (2018JS153);

Received Date: 2018-11-19

Abstract

Abstract

Hyperuricemia is a foundation of multiple diseases, and lowering serum uric acid is able to effectively prevent and treat the diseases such as gout, renal dysfunction and cardiovascular diseases. Recently, new achievements in study on hyperuricemia treatment and prevention were emerged, which needs to be summed up.At first, the present article briefly reviewed the synthesis and elimination of uric acid, and grouped the ways of prevention and treatment into three strategies: inhibiting synthesis, enhancing excretion, and promoting degradation. In the end, the article put forward that future strategy should focus on intestinal tract to lower serum uric acid by local rather than systematic administration.
- Herperuricemia,
- Xanthine oxidase inhibitor,
- Uricosurics,
- Urine alkalization,
- Urate oxidase

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References(26)

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