Wang Li Yu , He Hong Bing , Tan Jin Zhang , Ren Xiao Bin . Effect of Yunnan Baiyao on Cytokines Releasing from Platelet Rich-Fibrin in Human[J]. Journal of Kunming Medical University, 2019, 40(03): 35-38.
Citation: Wang Li Yu , He Hong Bing , Tan Jin Zhang , Ren Xiao Bin . Effect of Yunnan Baiyao on Cytokines Releasing from Platelet Rich-Fibrin in Human[J]. Journal of Kunming Medical University, 2019, 40(03): 35-38.

Effect of Yunnan Baiyao on Cytokines Releasing from Platelet Rich-Fibrin in Human

Funds:

基金: 国家自然科学基金资助项目 (8166040056); 云南省教育厅科学研究基金资助项目 (2016ZDX065); 昆明医科大学研究生创新基金资助项目 (2018S177);

  • Received Date: 2018-11-13
  • Objective To observe the variation in PRF before and after taking yunnan baiyao by detecting the concentration of three kinds of cytokines which are Platelet Derived Growth Factors (PDGF-AB) , Transforming Growth Factors (TGF-β) , Insulin-like Growth Factors (IGF) . Methods There were 3 volunteers who were approved by institutional ethical. We collected the venous blood 10 m L from them, in order to prepare for the PRF membrane. Then we put the blood under 37 ℃ and collected their exudates on 1 d, 7 d, 14 d, 21 d, 28 d separately, and used ELISA method to detect the concentration of the exudates. Results (1) The situation of the cytokines releasing: at different time points, TGF-β1 concentration were sable;on day 14 the concentration of PDGF-AB reached the highest, and on day 7 concentration of IGF-1 reached the peak. 2) After taking yunnan baiyao the concentration of cytokines was higher than before observably (P < 0.05) .Conclusion PRF can release the cytokines constantly, taking the yunnan baiyao can stimulate the PRF to release higher concentration of cytokines effectively.
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