Effect of Yunnan Baiyao on Cytokines Releasing from Platelet Rich-Fibrin in Human

Wang Li Yu; He Hong Bing; Tan Jin Zhang; Ren Xiao Bin

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Wang Li Yu , He Hong Bing , Tan Jin Zhang , Ren Xiao Bin . Effect of Yunnan Baiyao on Cytokines Releasing from Platelet Rich-Fibrin in Human[J]. Journal of Kunming Medical University, 2019, 40(03): 35-38.

Citation:

Wang Li Yu , He Hong Bing , Tan Jin Zhang , Ren Xiao Bin . Effect of Yunnan Baiyao on Cytokines Releasing from Platelet Rich-Fibrin in Human[J]. Journal of Kunming Medical University, 2019, 40(03): 35-38.

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Effect of Yunnan Baiyao on Cytokines Releasing from Platelet Rich-Fibrin in Human

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基金：国家自然科学基金资助项目 (8166040056); 云南省教育厅科学研究基金资助项目 (2016ZDX065); 昆明医科大学研究生创新基金资助项目 (2018S177);

Received Date: 2018-11-13

Abstract

Abstract

Objective To observe the variation in PRF before and after taking yunnan baiyao by detecting the concentration of three kinds of cytokines which are Platelet Derived Growth Factors (PDGF-AB) , Transforming Growth Factors (TGF-β) , Insulin-like Growth Factors (IGF) . Methods There were 3 volunteers who were approved by institutional ethical. We collected the venous blood 10 m L from them, in order to prepare for the PRF membrane. Then we put the blood under 37 ℃ and collected their exudates on 1 d, 7 d, 14 d, 21 d, 28 d separately, and used ELISA method to detect the concentration of the exudates. Results (1) The situation of the cytokines releasing: at different time points, TGF-β1 concentration were sable;on day 14 the concentration of PDGF-AB reached the highest, and on day 7 concentration of IGF-1 reached the peak. 2) After taking yunnan baiyao the concentration of cytokines was higher than before observably (P < 0.05) .Conclusion PRF can release the cytokines constantly, taking the yunnan baiyao can stimulate the PRF to release higher concentration of cytokines effectively.
- Yunnan baiyao,
- Platelet rich-fibrin,
- Cytokines

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References(17)

References

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