Clinical Characteristics of Brainstem Auditory Evoked Potential in Children with Brain Injury Syndrome

Liu Chun Ming; Liu Yun; He Li Ping; Zhang Yang Ping; Zhao Yi Bin; Zhou Yi Qing; Cao Xuan Lan; Deng Xiao Li

Article Contents

Article Navigation > Journal of Kunming Medical University > 2019 > 40(03): 78-82

Liu Chun Ming , Liu Yun , He Li Ping , Zhang Yang Ping , Zhao Yi Bin , Zhou Yi Qing , Cao Xuan Lan , Deng Xiao Li . Clinical Characteristics of Brainstem Auditory Evoked Potential in Children with Brain Injury Syndrome[J]. Journal of Kunming Medical University, 2019, 40(03): 78-82.

Citation:

Liu Chun Ming , Liu Yun , He Li Ping , Zhang Yang Ping , Zhao Yi Bin , Zhou Yi Qing , Cao Xuan Lan , Deng Xiao Li . Clinical Characteristics of Brainstem Auditory Evoked Potential in Children with Brain Injury Syndrome[J]. Journal of Kunming Medical University, 2019, 40(03): 78-82.

Citation:

Liu Chun Ming , Liu Yun , He Li Ping , Zhang Yang Ping , Zhao Yi Bin , Zhou Yi Qing , Cao Xuan Lan , Deng Xiao Li . Clinical Characteristics of Brainstem Auditory Evoked Potential in Children with Brain Injury Syndrome[J]. Journal of Kunming Medical University, 2019, 40(03): 78-82.

PDF( 1489 KB)

Clinical Characteristics of Brainstem Auditory Evoked Potential in Children with Brain Injury Syndrome

Funds:

基金：云南省卫生科技计划项目 (2016N8123); 昆明市卫生科技人才培养项目[2017-SW (后备) -68];

Received Date: 2018-10-15

Abstract

Abstract

Objective To provide evidences for early intervention in chidren with brain injury syndrome through studing the hearing characteristics and influencing factors in these children. Methods A total of 466 children with brain injury syndrome were selected who visited Kunming children's Hospital from June 2017 to June2018. All children were examined by brainstem auditory evoked potential (BAEP) . The premature infants group (34-37 weeks, 31-34 weeks, < 31 weeks threegroups) , hypoxia group (HIE and non-HIEtwo groups) and jaundice group (nuclear jaundice and non-nuclear jaundice twogroups) were analyzed statistically to compare the difference of hearing impairment rate and severity between different degreeof risk factors.Result The abnormal detection rate of BAEP was the highest in the nuclear jaundice group (51.9%) .There was no significant difference in the abnormal rate of BAEP among three groups of preterm infants of different gestational age (χ2= 5.826, P >0.05) , but there was significant difference in the degree of hearing impairment (Z = 11.837, P < 0.01) .The smaller the gestational age, the more serious the hearing damage. There was no significant difference in the abnormal rate of BAEP between HIE group and non HIE group ( χ2= 3.66, P > 0.05) , but there was significant difference in the degree of hearing impairment (Z =-2.107, P < 0.05) , hearing impairment in HIE group was more serious than that in non-HIE group. The abnormal rate of BAEP and the degree of hearing impairment were significantly different between the nuclear jaundice and non-nuclear jaundice. The abnormal rate of BAEP was higher and the degree of hearing impairment was more serious in the group of nuclear jaundice. (χ2= 22.286, P <0.01, Z =-2.666, P < 0.01) .Conclusions In the children with brain injury syndrome, the smaller the week of premature delivery, HIE and the nuclear jaundice, the more serious degree of hearing impairment. In children with hyper bilirubinemia, the rate of abnormal hearing in nuclear jaundice is higher than that in children without nuclear jaundice. Therefore, BAEP test should be performed as soon as possible to assess the hearing status of children with the above risk factors.
- Brain injury syndrome,
- Brainstem auditory evoked potential,
- Premature infant,
- Hypoxic-ischemic encephalopathy,
- Nuclear jaundice

FullText(HTML)

References(20)

References

[1]刘芸, 唐学兵.1268例高危儿的随访情况分析[J].中国妇幼保健, 2013, 28 (16) :2571-2573.
[2]胡秀珍.新生儿听力筛查结果分析及临床意义[J].现代诊断与治疗, 2012, 23 (7) :865-867.
[3] 刘振寰, 钱旭光.小儿脑损伤综合征的诊断与治疗[J].中国保健, 2006, 6 (1) :61-64.
[4]卜行宽, 听力损失分级问题的国际讨论, 中国医学文摘 (耳鼻咽喉科学) , 2012, 27 (6) :293-294.
[5]金汉珍, 黄德珉, 官希吉.实用新生儿学[M].第3版, 北京:人民卫生出版社, 2002:297-305.
[6]李浩, 肖婕, 李学章等.系统性缺氧导致新生大鼠脑损伤及远期行为异常[J].昆明医科大学学报, 2016, 37 (3) :8-12.
[7]方红, 史玫, 郭燕燕.脑干听觉诱发电位和闪光视觉诱发电位检测在新生儿缺氧缺血性脑病中的应用价值[J].新乡医学院学报, 2018, 35 (5) :418-420.
[8]陈平, 唐安洲.新生儿多种听损伤高危因素共存时的听性脑干反应特征分析[J].中华耳鼻喉头颈外科杂志, 2005, 40 (5) :335-338.
[9]黄燕, 黄丽辉.高危新生儿TEOAE和AABR听力筛查分析[J].听力学及言语疾病杂志, 2006, 14 (3) :221-222.
[10]万国兰, 金锦等.高危早产儿与高危足月儿脑性瘫痪的病残程度及脑干听觉诱发电位异常的对比研究[J].中国实用神经疾病杂志, 2009, 12 (8) :6-9.
[11]王小亚, 罗仁忠.早产极低出生体重儿听性脑干诱发电位特征分析[J].临床耳鼻咽喉头颈外科杂志, 2009, 23 (16) :746-751.
[12]徐发林, 邢秋景.听觉脑干反应和耳声发射在高危儿听力筛查中的应用[J].中国当代儿科杂志, 2008, 10 (4) :460-463.
[13]韩进天.高危儿的听力特点及相关因素分析[J]。广西医学, 2006, 28 (6) :828-829.
[14]王昕, 杨健.听觉诱发电位在重症脑功能检测中的应用[J].中国小儿急救医学, 2017, 24 (6) :420-424.
[15]冯英, 肖农, 陈玉霞, 等.体感诱发电位和脑干听觉诱发电位预测恢复期严重意识障碍患儿意识恢复的价值[J].临床儿科杂志, 2016, 34 (11) :806-810.
[16]叶同生, 张健, 胡克非, 等.磁共振波谱技术及脑干听觉诱发电位在新生儿早期胆红素脑病损伤中的评估作用[J].安徽医学, 2017, 38 (5) :552-555.
[17] 李红叶.脑干听觉诱发电位早期发现小儿脑损伤综合征听路损伤并干预[J].医学创新研究, 2008, 5 (26) :90-91.
[18]姜舟, 赵力立, 宋葳.听性脑干反应在新生儿缺氧缺血性脑病的听力损害研究及预后判断中的应用[J].中国循证医学杂志, 2013, 13 (7) :807-809.
[19]刘静, 张鸾, 王二艳, 等.高危早产儿早期行神经发育干预改善运动和认知发育的作用[J].昆明医科大学学报, 2016, 37 (3) :81-84.
[20]	[20]WENNBERGRP, AHLFORSCE, BHUTANIVK, et al.Towardundersdandingkernieterusia challenge to improve the management of jaundiced newborns[J].Pediatrics, 2006, 117 (2) :474-485.

Relative Articles(20)

Relative Articles

[1]	Shuang FANG, Libo ZHU, Ling LIU, Yanhua XU, Xue HU. Meta-analysis of the Impact of Early Enteral Nutrition on the Clinical Outcomes of Very Low Birth Weight Premature Infants. Journal of Kunming Medical University, 2024, 45(9): 129-135. doi: 10.12259/j.issn.2095-610X.S20240920
[2]	Yongyi ZOU, Zhiye QI, Dongmei SUN, Chunmei Wan, Kun LIANG. Effects of Different Vitamin D Doses on Bone Metabolism and Growth and Development Indicators of Preterm infants：A Cohort Study. Journal of Kunming Medical University, 2023, 44(11): 76-81. doi: 10.12259/j.issn.2095-610X.S20231111
[3]	Yanzheng YANG, Yue ZHOU, Tuan LI, Shuangyan CHEN. Efficacy of Pentatone Therapy Combined with Non-nutritive Sucking in Feeding Premature Infants. Journal of Kunming Medical University, 2022, 43(6): 171-176. doi: 10.12259/j.issn.2095-610X.S20220622
[4]	Jiarong YUAN, Ying LIANG, Jian MA, Chao QI, Nan LI. Effect of Early Physical Instruction on Development of Preterm Infants. Journal of Kunming Medical University, 2022, 43(3): 103-107. doi: 10.12259/j.issn.2095-610X.S20220323
[5]	Xian ZHANG, Lin ZHAO, Yan-hong LI, Jun-tao ZHANG, Meng-ru ZHAO. Application Value of IL-6, NES and Neonatal Craniocerebral UltrasoundIn Early Diagnosis of White Matter Injury in Premature Infants. Journal of Kunming Medical University, 2021, 42(3): 115-120. doi: 10.12259/j.issn.2095-610X.S20210329
[6]	Ting HU, Da-zhi CHEN, Jin-rong MA, Ping LI, Ze-lan MENG, Chun-hua LEI, Lei ZENG, Ju-ying PU, Fang GUO. Efficacy of Oral Immunotherapy with Colostrum on Preterm Very Low Birth Weight Infants. Journal of Kunming Medical University, 2021, 42(4): 172-175. doi: 10.12259/j.issn.2095-610X.S20210433
[7]	Zhou Yu E , Yin Li Juan , Yang Hui Bo . . Journal of Kunming Medical University, 2020, 41(02): 168-170.
[8]	Jiang Yan , Mi Hong Ying , Shi Xu Li , Yang Jing Hui , Yang Yong Mei , Tian Yun Fen . . Journal of Kunming Medical University, 2020, 41(06): 120-126.
[9]	Ding Su Zhen , Li Lan , Zhu He Fei , Li Shao Min , Dong Jie . . Journal of Kunming Medical University, 2019, 40(12): 34-38.
[10]	Zhou Yu E , Zhang Zheng Ming , Liao Gui . The Clinic Effect of 2-Hour Feeding in Premature Infants with Very Low Birth Weight. Journal of Kunming Medical University, 2018, 39(08): 145-148.
[11]	Li Ke Xing , Zou Yi , Zhang Li Jiao . Effect of Gangliosides in Improving the Cerebral Blood Flow and Nerve Function Indexes of Newborns with Hypoxic Ischemic Encephalopathy. Journal of Kunming Medical University, 2017, 38(04): 113-116.
[12]	Xiong Han Mei . . Journal of Kunming Medical University,
[13]	Peng Bo . . Journal of Kunming Medical University,
[14]	. Clinical Observation of Ritodrine Treat for the Ment of 32 Cases of Prematurity. Journal of Kunming Medical University,
[15]	. Clinical Observation on Large Dose of Ambroxol Hydrochloride in Prevention and Treatment of Neonatal Respiratory Distress Syndrome. Journal of Kunming Medical University,
[16]	. Therapeutic Effect of Large Dose of Mucosolvan on Respiratory Distress Syndrome in Premature Children. Journal of Kunming Medical University,
[17]	. Comparison of the Clinical Characteristics of Newborn Respiratory Distress Syndrome between Full-term and Premature Infants. Journal of Kunming Medical University,
[18]	He Li . . Journal of Kunming Medical University,
[19]	Zhang Yi . . Journal of Kunming Medical University,
[20]	Xu Hui . . Journal of Kunming Medical University,