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Baixue LIN, Lei ZHANG, Mingzhu GAO, Haimei SUN, Lifang YE, Ying WANG, Chan REN, Xiaorong YANG. Diagnostic Value of SIRI for Acute Ischemic Stroke-Associated Pneumonia of the Brain[J]. Journal of Kunming Medical University.
Citation: Baixue LIN, Lei ZHANG, Mingzhu GAO, Haimei SUN, Lifang YE, Ying WANG, Chan REN, Xiaorong YANG. Diagnostic Value of SIRI for Acute Ischemic Stroke-Associated Pneumonia of the Brain[J]. Journal of Kunming Medical University.

Diagnostic Value of SIRI for Acute Ischemic Stroke-Associated Pneumonia of the Brain

  • Received Date: 2024-03-28
    Available Online: 2024-04-29
  •   Objective  To investigate the predictive value of systemic inflammatory response index (SIRI) for acute ischemic stroke-associated pneumonia of the brain.   Methods  The baseline data of patients diagnosed with acute ischemic stroke in the First Affiliated Hospital of Kunming Medical University from January 2017 to December 2022 were gathered to calculate the SIRI index. Patients were divided into SAP group (665 cases) and Non-SAP (466 cases) group according to whether SAP occurred within 7 days of stroke onset. Logistic regression was used to analyze the relationship between SIRI index and SAP in patients with acute ischemic stroke-associated pneumonia of the brain, and ROC was used to analyze the predictive value of SIRI for SAP.   Results  The analysis included 665 patients with acute ischemic stroke whose median age was 67.00 (56.00~76.00) years old, and the incidence of SAP was 29.92%. The age, the incidence of atrial fibrillation, the use rate of acid suppressive drugs, the use rate of indwelling gastric tube, fasting blood glucose, the proportion of moderate and severe patients in the NHISS score, the number of white blood cells, neutrophils, monocytes, and SIRI index in the SAP group were higher than those in the non SAP group (P < 0.05). However, the hemoglobin value and lymphocyte number in SAP group were lower than those in non SAP group (P < 0.05). Logistic regression analysis showed that age, indwelling gastric tube, higher NHISS score group and SIRI index were the risk factors of SAP in patients with acute ischemic stroke. ROC analysis showed that the prediction accuracy of SIRI for patients with acute ischemic stroke-associated pneumonia of the brain was 0.707 (95%CI: 0.662~0.753, P < 0.001).   Conclusion  SIRI index is correlated with the occurrence of acute ischemic stroke- associated pneumonia and has the predictive value for it.
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