Correlation of Lung Function and HRCT Bronchial Wall Thickness in Patients with Chronic Obstructive Pulmonary Disease

Qian HUANG; Meihua LI; Xiaojing TANG; Wei MA; Yanxia YANG; Qingling ZHENG; Jin HE

doi:10.12259/j.issn.2095-610X.S20220224

Volume 43 Issue 2

Mar. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(2): 118-121

Qian HUANG, Meihua LI, Xiaojing TANG, Wei MA, Yanxia YANG, Qingling ZHENG, Jin HE. Correlation of Lung Function and HRCT Bronchial Wall Thickness in Patients with Chronic Obstructive Pulmonary Disease[J]. Journal of Kunming Medical University, 2022, 43(2): 118-121. doi: 10.12259/j.issn.2095-610X.S20220224

Citation:

Qian HUANG, Meihua LI, Xiaojing TANG, Wei MA, Yanxia YANG, Qingling ZHENG, Jin HE. Correlation of Lung Function and HRCT Bronchial Wall Thickness in Patients with Chronic Obstructive Pulmonary Disease[J]. Journal of Kunming Medical University, 2022, 43(2): 118-121. doi: 10.12259/j.issn.2095-610X.S20220224

Citation:

Qian HUANG, Meihua LI, Xiaojing TANG, Wei MA, Yanxia YANG, Qingling ZHENG, Jin HE. Correlation of Lung Function and HRCT Bronchial Wall Thickness in Patients with Chronic Obstructive Pulmonary Disease[J]. Journal of Kunming Medical University, 2022, 43(2): 118-121. doi: 10.12259/j.issn.2095-610X.S20220224

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Correlation of Lung Function and HRCT Bronchial Wall Thickness in Patients with Chronic Obstructive Pulmonary Disease

doi: 10.12259/j.issn.2095-610X.S20220224

1.
Dept. of Respiratory and Critical Care Medicine，The First People’s Hospital of Kunming，Kunming Yunnan 650011
2.
Dept. of CT Division，The First People’s Hospital of Kunming，Kunming Yunnan 650011，China

Received Date: 2021-12-19
Available Online: 2022-02-24
Publish Date: 2022-03-04

Abstract

Abstract

Objective To investigate the correlation of pulmonary function indexes and bronchial wall thickness measured as computed with high resolution computed tomography in patients with chronic obstructive pulmonary diseases. Methods Eighty COPD patients were assigned to four groups based on the new COPD Global Initiative Classification, meanwhile, fifty normal people with physical examination in the hospital were selected as controls simultaneously. All subjects underwent chest HRCT scanning to measure the bronchial wall thickness at the bilateral apical bronchial opening, and the correlation between the bronchial wall thickness and lung function was studied. Results Bronbronchial wall thickness was significantly increased in COPD patients compared with normal population, and the difference was statistically significant （P < 0.05）. From the mild group to the very severe group, the bilateral bronchial wall thickness gradually increased, FEV1, FVC, FEV1/FVC gradually decreased, with statistically significant differences （P < 0.05）. Correlation analysis: bilateral bronchial wall thickness was significantly inversely associated with each index of lung function （P < 0.05）. Conclusions HRCT can be used to measure bronchial wall thickness and evaluate the degree of bronchial wall remodeling in COPD patients. With the deepening of the disease grade, the thickness of the bronchial wall of COPD patients gradually increased. There is a significant correlation between lung function indexes and bronchial wall thickness, that is, the thickening of bronchial wall, the decline of lung function indexes and the deterioration of lung function. HRCT measurement of bronchial wall thickness in COPD patients has clinical significance for the evaluation of the severity of the disease.
- Chronic obstructive pulmonary disease,
- High resolution computed tomography,
- Lung function,
- Bronchial wall thickness.

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References(12)

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