Chen Shan Shan , Tao Si Ming , Han Ming Hua . Clinical Observation on Treatment of Coronary Heart Disease Angina by Enough Metoprolol[J]. Journal of Kunming Medical University, 2017, 38(11): 101-103.
Citation: Chen Shan Shan , Tao Si Ming , Han Ming Hua . Clinical Observation on Treatment of Coronary Heart Disease Angina by Enough Metoprolol[J]. Journal of Kunming Medical University, 2017, 38(11): 101-103.

Clinical Observation on Treatment of Coronary Heart Disease Angina by Enough Metoprolol

Funds:

基金: 云南省应用基础研究基金资助项目 (2013FB182);

  • Received Date: 2017-05-19
  • Objective To observe the effect, toleration and safety of metoprolol in treatment of coronary heart disease angina.Methods Ninety-eight patients with confirmed coronary heart disease were randomly divided into two groups:control group and metoprolol treatment group.Patients in the metoprolol treatment group were given metoprolol sustained release tablet treatment on the basis of regular drug treatment, and the dosage of metoprolol was increased gradually to the maximum tolerated dose.Patients in the control group were given regular drug treatment.All patients were followed up for half a year.The heart rate, blood pressure, the frequency of the angina attack, cardiac function and ECG were observed to compare the clinical effect between two groups.Results The clinical effect in the metoprolol treatment group was significantly better than the control group.There were statistically significant difference between control group and metoprolol treatment group (P<0.05) .Conclusion Enough metoprolol sustained release tablets can significantly improve the clinical symptoms of coronary heart disease.
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