Clinical Study of SPECT-CT Radionuclide Imaging in Eustachian Tube Function
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摘要:
目的 探讨SPECT-CT核素显像在中耳炎咽鼓管功能检查的应用。 方法 选取2019年4月至2020年5月昆明医科大学第一附属医院耳鼻咽喉科收治的慢性化脓性中耳炎(A组)、中耳胆脂瘤(B组)及外伤性鼓膜穿孔(C组)的患者40例分为3组,均行咽鼓管SPECT-CT核素显像(观察组),Valsalva检查(对照组),对3组患者的基本资料和研究情况进行统计学分析。 结果 A组、B组与C组行咽鼓管SPECT-CT核素显像咽鼓管阻塞程度比较,采用χ2检验,差异有统计学意义(P < 0.05);A组、B组与C组行咽鼓管SPECT-CT核素显像(观察组)与Valsalva检查(对照组)的比较,采用χ2检验,差异有统计学意义(P < 0.05)。 结论 说明咽鼓管阻塞是中耳炎的病因、治疗中的一个重要的因素,咽鼓管SPECT-CT核素显像可以动态观察咽鼓管阻塞的程度,有助于咽鼓管阻塞部位的判断。 Abstract:Objective To investigate the application of SPECT-CT radionuclide imaging in function examination of eustachian tube in otitis media patients. Methods 40 patients with chronic suppurative otitis media (group A), cholesteatoma of the middle ear (group B) and traumatic tympanic membrane perforation (group C) admitted from April 2019 to May 2020 were divided into three groups, all of them underwent eustachian tube SPECT-CT radionuclide imaging and Valsalva examination. Results Comparison of eustaginal tube obstruction in group A, B and C with THE X2 test, P < 0.05, the difference was statistically significant. Comparison of group A, B and C with eustachian tube SPECT-CT radionuclide imaging (observation group) and Valsalva examination (control group) by X2 test, P < 0.05, the difference was statistically significant. Conclusions Eustachian tube obstruction is an important factor in the etiology and treatment of otitis media. Eustachian tube SPECT-CT radionuclide imaging can dynamically observe the degree of eustachian tube obstruction, help to judge the location of eustachian tube obstruction and provide clinical services. -
Key words:
- Nuclide imaging /
- Otitis media /
- Eustachian tube
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表 1 3组行咽鼓管SPECT-CT核素显像检查咽鼓管阻塞的比较[n(%)]
Table 1. Comparison of eustachian tube obstruction with SPECT-CT radionuclide imaging in groups A, B and C [n (%)]
组别 阻塞 通畅 合计(n) 阻塞率(%) A组 11(78.6) 3(21.4) 14 78.6* B组 17(80.9) 4(19.1) 21 80.9* C组 1(20.0) 4(80.0) 5 20.0 与C组比较,*P < 0.05。 表 2 观察组与对照组咽鼓管阻塞率的比较[n(%)]
Table 2. Comparison of eustachian tube obstruction between observation group and control group [n(%)]
组别 A组(n = 14) B组(n = 21) C组(n = 5) 观察组 11(78.6) 17(80.9) 1(20.0) 对照组 5(35.7) 10(47.6) 3(60.0) χ2 5.250 5.081 0.417 P 0.022* 0.024* 0.519 *P < 0.05。 -
[1] 韩德民. 耳鼻咽喉头颈科学[M]. 北京: 北京大学医学出版社, 2004: 36-39. [2] Proctor B. Anatomy of the eustachian tube[J]. Arch Otolaryngol.,1997,14(8):2-5. [3] 龚树生. 咽鼓管功能障碍研究及治疗现状[J]. 中国医学文摘(耳鼻咽喉科学),2015,30(6):298-303. [4] 龚树生,熊伟. 慢性中耳炎的规范化诊治[J]. 临床耳鼻咽喉头颈外科杂志,2017,31(16):1221-1224. [5] Bhutta M F. Epidemiology and pathogenesis of otitis media:construction of a phenotype landscape[J]. Audiol Neurotol,2014,19(4):210-223. [6] Verhoeff M,Vander Veen E L,Rovers M M,et al. Chronic suppurative otitis media:a review[J]. Int J Pediatr Otorhinolaryngol,2006,70(2):1-12. [7] 甄宏韬,王春芳,崔永华,等. 正常人咽鼓管功能的综合法检测[J]. 临床耳鼻咽喉科杂志,2000,14(4):160-161. doi: 10.3969/j.issn.1001-1781.2000.04.006 [8] 中华医学会. 临床技术操作规范核医学分册[M]. 北京: 人民军医出版社, 2004: 45-46. [9] 罗强,胡小怡,黄斌豪,等. 99Tc-DTPA咽鼓管显像临床应用[J]. 中华核医学杂志,2003,23(2):117. [10] 王蕴弼, 靳惠民, 王来好, 等. 99 Tcm 咽鼓管γ照相机的应用. 中华耳鼻咽喉科杂志, 1995, 30(2): 186-187. [11] 王胜利,计学理,刘建功,等. 鼓室注射(99m)锝核素显像对咽鼓管疾病的诊断[J]. 临床耳鼻咽喉头颈外科杂志,2010,24(19):901-902. [12] 王胜资,严月华,沈爱琴. 鼓膜置管后咽鼓管造影CT扫描的意义[J]. 临床耳鼻咽喉科杂志,1997,11(3):125-126. [13] 申力,徐孔昌,李界文,等. 咽鼓管造影CT扫描诊断咽鼓管阻塞的意义[J]. 听力及言语疾病杂志,2008,16(6):488-490. [14] MCCOUL ccoulE D,ANAND nandV K,CHRISTOS hristosP J. validating the clinical assessment of eustachian tube dysfunction:The Eustachian Tube Dysfunction Questionnaire(ETDQ-7)[J]. laryngoscope,2012,122(11):1137-1141. [15] 陈彬,高下,俞晨杰,等. 七项咽鼓管功能障碍症状评分量表的应用分析[J]. 中华耳科杂志,2016,14(3):403-406. [16] Mandei E M,swartsj D. Casselbrant M L,et al. Eustachian tube function as a predictor of the recurrence of middle ear effusion in children[J]. J laryngoscope,2013,123(9):2285-2290. doi: 10.1002/lary.24021 [17] 袁媛,李桂芝,周卫东,等. 咽鼓管咽口及其周围形态学改变与分泌性中耳炎的相关性研究[J]. 临床耳鼻咽喉头颈外科杂志,2007,22(18):1860-1862. [18] D annerC J. Middle ear atelectasis: what causes it and how is it corrected?[J]. Otolaryngol Clin North Am, 2006, 39(8): 1211-1219. [19] 陈晓欣,梁茂金,司瑜,等. 阻塞性咽鼓管功能障碍治疗进展[J]. 国际耳鼻咽喉头颈外科杂志,2021,45(2):100-103. doi: 10.3760/cma.j.issn.1673-4106.2021.02.010 [20] 朱栓庄,叶梦晓,邓锡汤,等. 4DCT在咽鼓管功能障碍患者咽鼓管功能评估中的应用[J]. 中国耳鼻咽喉头颈外科,2021,28(1):18-21. [21] 曾镇罡,高一铭,孙佳玉,等. Ⅰ型鼓室成形术中咽鼓管功能的评估及其对疗效的影响[J]. 中华耳科学杂志,2021,19(1):61-65. doi: 10.3969/j.issn.1672-2922.2021.01.011