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Supervisor：Education Department of Yunnan Province Sponsor：Kunming Medical University Chief Editor：Xia Xueshan

ISSN 2095-610X CN 53-1221/R

Address：1168 Chunrong West Road, Yuhua street, Chenggong New City, Kunming

Postal Code：650500 Telephone：0871－65936489 

E-mail：kmykdxxbzk@163.com

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Articles just accepted have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
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Application of Serum STAT3，HDAC2，and Del-1 Levels in the Evaluation of Disease Severity and Prognosis of Children with Respiratory Syncytial Virus Pneumonia
Hongyan CUI, Shuyang ZHANG, Wenwen ZHOU
Abstract(31) PDF(2)
Correlation of Serum miR-21 and miR-23a Levels with Cognitive Function and Inflammatory Response in Patients with Parkinson’ s Disease
Zhiping HAN, Jing CHEN, Tao MA, Shaolan WANG, Jiandong LÜ
Abstract(39) PDF(1)
Clinical Study on Predicting Pregnancy Outcomes through The Imbalance of Vaginal Microbiota and Levels of Inflammatory Factors in Pregnant Women
Qing LI, Wei GENG, Fengxi ZHANG, Dan ZHANG
Abstract(151) PDF(1)
Investigating the Effect of Dihydroartemisinin on Proliferation and Metastasis of Prostate Cancer Cells based on the SPOP/HnRNPK Pathway
Jiantong ZHANG, Zhenzhuang GAO, Zhixiu WANG, Lina SUN
Abstract(26) PDF(0)
Mechanism by Which T Cell Immune Structural Proteins Promote the Role of the Hippo Pathway in the Pathogenesis of Preeclampsia
Weiyi ZHANG, Liping YANG, Jiancai MA
Abstract(28) PDF(0)
Factors Influencing Respiratory Syncytial Virus Infection in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Correlation with Serum Levels of HSP70，KLF5，MIP-2
Xianbiao XU, Mingfang YANG, Ruidan LI, Li ZHANG
Abstract(29) PDF(1)
Analysis of Factors Influencing Recurrence in Osteosarcoma Patients and Construction of Nomogram Prediction Model
Guoyu MA, Xin YANG, Weilin SHAO, Chuqi QUAN, Xiaohui YANG, Zuozhang YANG, Zhihong YAO
Abstract(38) PDF(1)
Changes in Ang-2 Levels Before and after Microwave Ablation Treatment in High-Risk Pulmonary Nodule Patients and Its Impact on Postoperative Recurrence
Yuxiang ZHOU, Guangjun MIAO, Honghong XIAN, Jiangrong LIAO
Abstract(37) PDF(1)
Analysis of Thalassemia Gene Screening and Diagnosis Results in the Dehong Population
Peng LI, Wei YI, Jie ZHANG, Yangjia ZHANG, Shijun GE
Abstract(48) PDF(3)
Expression of Cell Pyroptosis-Associated TLR4 Signalling Pathway During the Progression from Actinic Keratosis to Cutaneous Squamous Cell Carcinoma
Xiaoyu ZHAO, Minyan ZHANG, Huiya CHEN, Tingting CUI, Yuhan HUANG, Dan XU
Abstract(40) PDF(0)
Changes in Expression Levels and Clinical Significance of Park7 and P2X7R in the Serum of Patients with Acute Myocardial Infarction
Xuemei WANG, Haiqing CHEN, Lina CHEN
Abstract(31) PDF(0)
Molecular Mechanism of the YAP1/ANXA2 Signaling Axis in Regulating Apoptosis and Migration of Renal Tubular Epithelial Cells
Shaoting SUN, Lanmei LI, Weiwei BAI, Na CHEN, Meng WANG, Ming ZHANG, Yafen LI
Abstract(51) PDF(0)
Disease Spectrum Analysis of Oral Cavity and Throat Malignant Tumors in the First People’s Hospital of Yunnan Province from 2012 to 2021Epidemiological Analysis of Head and Neck Malignant Tumors in a Hospital from 2012 to 2021
Fan WANG, Rong ZENG, Mao ZHANG, Yi REN, Hao DING
Abstract(47) PDF(0)
RBBP7 Promotes the Malignant Progression and Radioresistance of Esophageal Cancer through Hippo Signaling Pathway
Zhiyu MA, Jie ZHENG
Abstract(59) PDF(0)
Articles in press have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
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The Role of APOE4 in Regulating LRP1 on Aβ25-35-Induced Oxidative Stress and Inflammatory Response in Astrocytes
Yanping LI, Efty Fariha Tasnim, Zhixing LU, Lingying ZHU
Abstract(0) PDF(0)
The Levels of Serum CXCL5，TLR4，and MMP-3 in Gouty Arthritis Patients with Different Clinical Features and Their Correlation with the Joint Destruction and Serum Uric Acid Levels
Xiaohua LI, Yalu FU, Dan WANG
Abstract(39) PDF(1)
Research on an Educational Milestone System for Nursing Students in Bachelor's，Master's，and Doctoral Programs
Yuxin HAN, Yu ZHANG, Xinhui WANG, Yuping LI, Rong RONG, Shuowei ZHANG
Abstract(47) PDF(2)
A Study on the Application of the Timing-It-Right Framework Combined with Phase I Cardiac Rehabilitation Model in Patients Undergoing Transcatheter Aortic Valve Replacement
Wenming CHEN, Jinghong PI, Xintong FU, Yueqing CHEN, Hua LI,
Abstract(31) PDF(3)
Intervention of AKR1C3 on Malignant Biological Behavior of Breast Cancer Cells through PD1/PD-L1 Signaling Pathway
Jingjing SONG, Wei XIONG, Shuhui YAO, Shuang LIU, Jing ZHANG
Abstract(87) PDF(8)
Research Advances in D-dimer/Fibrinogen Ratio and Fibrinogen/Albumin Ratio in Acute Coronary Syndromes
Jizhou LI, Hongwei LI, Ye ZHANG, Hongling YANG
Abstract(43) PDF(1)
Effect of Xiyanping on Inflammatory Microenvironment of COPD Model Based on TLR3-MAPK Signaling Pathway
Juan LI, Meiling WANG, Lihong LIU
Abstract(134) PDF(6)
Impact of Hospital-Community-Family Linkage Model Intervention on Patients with Schizophrenia during the Post-Discharge Rehabilitation Period
Shu TAN, Jing ZENG, Runjuan MA, Wensa YIN
Abstract(149) PDF(11)
Relationship between Serum PON-1，NDRG4 and SFRP4 Expression，Peripheral Blood Immune Cell Distribution，and Prognosis in Gastric Cancer Patients
Tian TIAN, Xiaodong YANG, Shujie GE
Abstract(57) PDF(6)
Weight Gain Pattern during Pregnancy and Its Association with Delivery Fear and Cesarean Section Rate in Primiparous Women
Xiaoli CHAI, Li LI, Zhigang LIU, Wenyu YAN
Abstract(98) PDF(2)
Inhibitory Effect of Low-Molecular-Weight Heparin and Insulin Supplemented with Fenofibrate Capsules on Local Inflammation in Patients with Hypertriglyceridemic Acute Pancreatitis
Yao TANG, Ting XU, Jun WU
Abstract(73) PDF(5)
Gastrodin Ameliorates Maternal-Fetal Interface Injury in Gestational Diabetes Mellitus Rats by Activating the GPR120/AMPK Pathway
Nan LI, Ziyi NIU, Lan SHAO
Abstract(72) PDF(4)
Survey on Mental Disorders in HIV/AIDS Patients with End-stage Renal Disease on Hemodialysis
Guonian HE, Yongmei JIN, Bo TIAN, Shoukun CHEN, Nihong LU, Jun LIU
Abstract(91) PDF(9)
Studies on the Correlation between Esophageal Manometry and Short-Term Efficacy of Endoscopic Myomectomy in Patients with Achalasia
Yingye SONG, Juanping LI, Rui LI
Abstract(102) PDF(22)
Analysis of the Value of Serum Testosterone，Sex Hormone-Binding Globulin and Vitamin D Levels in Predicting Gestational Diabetes Mellitus Complicated by Polycystic Ovary Syndrome
Yuzhen ZHAO, Yingyan MA, Lili HE
Abstract(172) PDF(24)
The Relationship between PBEF，KLF2，IL-26 and The Condition and Prognosis of Severe Pneumonia in Children
Yan ZHANG, Yun TANG
Abstract(45) PDF(0)
Comparative Analysis of caIMR and CMR in Assessing Coronary Microvascular Dysfunction and Correlation of Cardiac and Cerebral Microvascular Lesions
Min YU, Lin SUN
Abstract(79) PDF(4)
Expert Consensus on the Diagnosis and Treatment of Chronic Coronary Syndrome with Traditional Chinese and Western Medicine in Yunnan Province
Li ZHANG, Ying ZHANG, Xueya ZHANG, Zhuo YU
Abstract(282) PDF(10)
Column
Expert Forum
Clinical Applications and Potential Mechanisms of Repetitive Transcranial Magnetic Stimulation in Prolonged Disorders of Consciousness
Jianlin PU, Jing FU, Zhong LI, Qiuyue MAO, Hongpeng LIU, Yadong LIU, Xuesong GAI
2025, 46(10): 1-11.    doi: 10.12259/j.issn.2095-610X.S20251001
Abstract(207) HTML PDF(12)
Original Articles Basic of Medicine
Epidemiological Characteristics of Venomous Snakebite in Yunnan Province
Qinfen GAO, Shegang LI, Jun LIU, Yan TANG, Fajun YANG, Yaowu CHEN, Wei ZHANG
2025, 46(10): 12-22.    doi: 10.12259/j.issn.2095-610X.S20251002
Abstract(186) HTML PDF(18)
miR-16-5p Promotes Inflammation and Apoptosis in Oxygen-Glucose Deprivation Microglia Model by Mediating GPR30 Expression
Zhiyong LI, Zhenggang CHEN, Jun PENG, Dazhong LIANG
2025, 46(10): 23-31.    doi: 10.12259/j.issn.2095-610X.S20251003
Abstract(98) HTML PDF(6)
Effect of SLC7A11 Gene on Progression of Hepatocellular Carcinoma by Regualating Iron Death Pathway
Liuzheng LI, Leisheng XU, Kanghong LUO, Mingting ZHANG, Yan WANG, Xuechang GAO, Jiawei FENG, Guocha GONG
2025, 46(10): 32-43.    doi: 10.12259/j.issn.2095-610X.S20251004
Abstract(81) HTML PDF(6)
Shikonin Induces Ferroptosis through ROS/JNK Pathway to Intervene in the Malignant Behavior of Pancreatic Cancer
Ruifeng QIN, Jiadong XUE, Jia ZHANG, Fan LIU, Shaohui ZHANG, Liyang YIN, Zengjiang YUAN
2025, 46(10): 44-52.    doi: 10.12259/j.issn.2095-610X.S20251005
Abstract(110) HTML PDF(5)
miR-147a Regulates Ferroptosis and Affects Invasion and Metastasis of Cervical Cancer Cells
Chunyu ZHANG, Jian LUO, Qi ZHOU
2025, 46(10): 53-60.    doi: 10.12259/j.issn.2095-610X.S20251006
Abstract(30) HTML PDF(4)
Epidemiological Characteristics of Respiratory Virus Infections in Kunming Region during 2023-2024
Dongling LI, Guangfeng YIN, Tingting YU, Songpeng LI, Shuqiong ZHANG, Dong PU
2025, 46(10): 61-69.    doi: 10.12259/j.issn.2095-610X.S20251007
Abstract(49) HTML PDF(4)
Clinical Research
Application of Electroacupuncture for Pain Management in Laparoscopic Cholecystectomy Patients
Jiaqi LIU, Haiqian ZHAO, Jianqing ZHANG, Ningli ZHANG, Jie OUYANG, Ying CHEN
2025, 46(10): 70-76.    doi: 10.12259/j.issn.2095-610X.S20251008
Abstract(35) HTML PDF(3)
Association of Serum Magnesium and Phosphorus with Vascular Calcification and Cardiovascular Events in Hemodialysis Patients
Zhiwei WEI, Chunming JIANG, Wei ZHOU, Bai ZHA
2025, 46(10): 77-84.    doi: 10.12259/j.issn.2095-610X.S20251009
Abstract(149) HTML PDF(7)
Clinical Relationship between Glycolysis，Iron Metabolism Indicators and Cardiovascular Status in Patients with Chronic Obstructive Pulmonary Disease-Coronary Artery Disease
Bin FANG, Yunpeng HU, Na HAO
2025, 46(10): 85-90.    doi: 10.12259/j.issn.2095-610X.S20251010
Abstract(29) HTML PDF(2)
Predictive Value of Serum miRNA-126a and miRNA-130b Levels in Cognitive Impairment among Patients with Diabetes Mellitus Complicated with Acute Stroke
Lingli LIU, Ruoxuan WEI, Wei CHEN, Caixia KONG, Zhihong LIU
2025, 46(10): 91-96.    doi: 10.12259/j.issn.2095-610X.S20251011
Abstract(41) HTML PDF(1)
Clinical Application of NETs in Diagnosis and Monitoring of Acute Ischemic Stroke
Wendi YANG, Yaxin WANG, Jing QIAN, Limin YIN, Fengting MU, Xiaoli ZHAO
2025, 46(10): 97-105.    doi: 10.12259/j.issn.2095-610X.S20251012
Abstract(120) HTML PDF(6)
Clinical Diagnostic Value of CT Combined with MR in Grading Sacroiliac Joint Lesions in Ankylosing Spondylitis
Xuenan WU, Huawei SU, Man LI
2025, 46(10): 106-112.    doi: 10.12259/j.issn.2095-610X.S20251013
Abstract(34) HTML PDF(3)
Clinical Value of AI-Assisted Transvaginal Color Ultrasound Combined with Serum Markers in Diagnosing Heterotopic Pregnancy after IVF-ET
Li ZHU, Heli LIU, Jian MAO, Bin ZHENG, Shuqun WANG
2025, 46(10): 113-120.    doi: 10.12259/j.issn.2095-610X.S20251014
Abstract(25) HTML PDF(2)
Study on Predictive Parameters of Liver Fibrosis Risk in Patients with Metabolic Dysfunction-associated Fatty Liver Disease Complicated with Chronic Hepatitis B
Yixin WANG, Fang WANG, Xiangyan WEI, Haiyang JIANG, Airong CHEN
2025, 46(10): 121-128.    doi: 10.12259/j.issn.2095-610X.S20251015
Abstract(30) HTML PDF(4)
Effects of Early Statin Therapy on Collateral Circulation，Responsible Vessels，and TXB2/PGF1α in Large Artery Occlusive Stroke
Fei YANG, Jing LI, Yanjun CHEN, Xuemei WU, Guoyong REN
2025, 46(10): 129-136.    doi: 10.12259/j.issn.2095-610X.S20251016
Abstract(48) HTML PDF(1)
Reviews
Infection Mechanism and Detection of Occult Hepatitis B Virus in Voluntary Blood Donors
Pei LIU, Boyu ZHANG, Wei LI, Youbin DUAN
2025, 46(10): 137-144.    doi: 10.12259/j.issn.2095-610X.S20251017
Abstract(118) HTML PDF(8)
Beverage Interventions in Metabolic Dysfunction-associated Steatotic Liver Disease
Jiawen WEI, Meng XIA, Yujun CHEN, Yong YANG, Ying ZHANG, Jiangyin ZHANG, Kuikui CHEN, Xianglong QIU
2025, 46(10): 145-155.    doi: 10.12259/j.issn.2095-610X.S20251018
Abstract(175) HTML PDF(13)
Teaching Research
Application of the Blended 5MP Teaching Model in the Education of Nursing Students in the Operating Room
Tingyan ZHU, Wenjing XIE, Luodan FAN, Liqiong HOU, Hong JIAN, Yunshan LIAO
2025, 46(10): 156-161.    doi: 10.12259/j.issn.2095-610X.S20251019
Abstract(136) HTML PDF(8)
Nursing Forum
Research Integrity，Awareness，and Influencing Factors of Clinical Nursing Personnel in a University-Affiliated Hospital
Xiaoliang DU, Xiaoqin GONG, Siyuan HUANG, Yushan LI
2025, 46(10): 162-171.    doi: 10.12259/j.issn.2095-610X.S20251020
Abstract(119) HTML PDF(9)
Correlation between Illness Benefits Perception，Coping Strategies，and Social Support among Type 2 Diabetes Patient Caregivers
Min HU, Min LI, Mengjing HAN, Yourong ZHANG, Zhijie DU, Na YAO
2025, 46(10): 172-178.    doi: 10.12259/j.issn.2095-610X.S20251021
Abstract(36) HTML PDF(1)

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