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Supervisor：Education Department of Yunnan Province Sponsor：Kunming Medical University Chief Editor：Xia Xueshan

ISSN 2095-610X CN 53-1221/R

Address：1168 Chunrong West Road, Yuhua street, Chenggong New City, Kunming

Postal Code：650500 Telephone：0871－65936489 

E-mail：kmykdxxbzk@163.com

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Articles just accepted have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
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Analysis of HPV Positivity Rates and High-Risk Genotypes among Multi-Ethnic Women Aged 35-64 in Lijiang City，Yunnan Province
Junqiang WANG, Limei ZHAO, Ping HE, Jinkun XIONG, limei HE, Kaixiang QIAN
Abstract(1) PDF(0)
Dexmedetomidine Ameliorates Pain-depression Comorbidity and Downregulates TAZ Expression in Spinal Microglia in Rats
Han ZENG, Can AN, Wenfeng LI, Mingyuan LIU, Shixiang ZHAO, Zhigui LI, Jiayu CHEN, Na LI
Abstract(126) PDF(1)
ncc-audit-test-045cc890
Abstract(90)
The Relationship between Serum sTREM-1，CCR1，LGALS3BP Expression and HBV-DNA Load，Liver Function，and Degree of Liver Fibrosis in Patients with Chronic Hepatitis B
Ying ZHANG, Pan ZHANG, Jingni ZHANG
Abstract(575) PDF(88)
Effects of MOGAT1 and Androgen Receptor on the Pathogenesis of Acne in Mice
Hongchao ZOU, Wei ZHU, Ran SHEN, Rui LI, Zhao ZHANG
Abstract(545) PDF(100)
Genetic Structure Analysis and Kinship Inference in a Male Pedigree Based on Next-generation Sequencing
Yifei ZENG, Jiamei JIANG, Junwei RUAN, Yan XIANG, Linlin LIU, Shengjie NIE, Liping HU
Abstract(0) PDF(0)
Epidemiological Characteristics and Trends of Malignant Tumors in Shidian County，Yunnan Province，2016–2023
Xinhui WU, Dongsheng HUANG, Yanyan YANG, Min ZHAO
Abstract(3) PDF(0)
Effects of Notoginsenoside R1 on Characteristics of Esophageal Squamous Cell Carcinoma KYSE150 Cells
Jinling XIAO, Ruiyan LIU, Xinyu LI, Junrun ZENG, Liping ZHANG, Yu GUO
Abstract(1) PDF(0)
Diterpenoids Derived from Strophioblachia Fimbricalyx Regulate Cardiac Hypertrophy by Blocking Autophagic Flux
Jing YUAN, Xin MA, Hongye ZHANG, Changbo ZHENG
Abstract(4) PDF(0)
Core Strategies of Engineered Bacteriophages and Research Progress in Their Application for Disease Treatment
Xuelin LI, Zehua HAN, Xiaoyan YANG, Runzhe HE, Wenteng HOU, Ai YANG, Yuliang CHEN, Yingying XIANG
Abstract(2) PDF(0)
Effect of Azithromycin Sequential Therapy Combined with Methylprednisolone on Pulmonary Function Indices and Immune Indices in Children with Severe Mycoplasma Pneumonia
Lan LIU, Xuejun ZHAO, Hongju FANG
Abstract(14) PDF(0)
Typing Study of Selective Fetal Growth Restriction in Twins: A comparative Analysis of Clinical Features and Pregnancy Outcomes among Different Types
Tingting ZHAO, Xie WANG, Xiaoyan ZHANG, Jing ZHAO
Abstract(8) PDF(0)
Characteristics of Inflammatory Cytokines and Prognostic Predictive Value in Breast Cancer Patients with Sleep Disorders
Xiuhong ZHANG, Gaijun ZHU, Lihui DONG
Abstract(15) PDF(0)
Epidemiological Characteristics of G6PD Deficiency in the Dai Population of Yunnan Province and a Pedigree Study on the Effects of X-Chromosome Inactivation on Female Phenotypes
Yuecheng YANG, Xiaolai ZHANG, Fang LIU, Jie ZHANG, Ming HE, Wei YI, Junxue NI
Abstract(22) PDF(0)
Association Between Hepatitis B Virus Serological Patterns and Hepatocellular Carcinoma: A Case-Control Study
Quansong XIA, Chuanqiong WANG, Lihong DUAN, Juan XU, Yu’e JIANG
Abstract(36) PDF(3)
Early Warning Value of Netrin-1，miR-144 and miR-21 for Miscarriage in Patients with PCOS Infertility
Yi ZENG, Honggui PAN, Binmei LONG
Abstract(16) PDF(0)
Research on the Layout of Medical and Health Vocational College Specialties in Yunnan in the Context of Comprehensive Health and Pathways for Optimization
Jian MA, Junmei LI, Jingling CHEN, Yuhan ZHANG, Jiali LIU, Pengbo LIU, Chaoliang YU, Jianyun YU
Abstract(31) PDF(0)
Research on Risk Assessment of High-risk Plaque Risk Based on Pericoronary Fat Quantification via CCTA
Saiyue WU, Hui DUAN, Dan HAN
Abstract(19) PDF(1)
Effects of High-Frequency rTMS Combined with Virtual Reality Balance Training in Patients with Hemiplegia After Stroke
Yuanyuan TANG, Sainan WANG, Aoran YANG
Abstract(29) PDF(2)
Staged Post-gastric Cancer Nutritional Management: Quantitative Target，Dynamic Feedback，and Application
Lianwei LIU, Aoran FAN, Xin YAO, Xiumin ZHANG
Abstract(23) PDF(0)
Application of a Multidisciplinary Collaboration Model in Patients with Chronic Obstructive Pulmonary Disease Based on Standardized Rosenthal Effect Intervention and Its Impact on Disease Cognition and Respiratory Symptoms
Chunmei CHEN, Lingling YU, Jie Zhang, Xuemei Zeng
Abstract(24) PDF(0)
Construction，Validation，and Explainability Study of a Hypertension Risk Identification Model Based on Machine Learning
Wenjun LI, Lang FANG, Yanmei JI, Meirong YANG, Ni MENG, Xinyi LIU, Xingfang JIN
Abstract(30) PDF(0)
The Effect of GSPs-TACE on the Growth of Liver Transplant Tumors in Rabbits
Chunhai HAO
Abstract(469) PDF(70)
The Association Between Serum sCD40L and Myocardial Injury in Acute Myocardial Infarction
Yiying DU, Kecheng WANG, Xin ZHANG, Xilong HU
Abstract(445) PDF(100)
Combined Predictive Value of miR-140-5p，miR-20b-5p and miR-421 in Nasopharyngeal Carcinoma Tissues for Radiosensitivity
Shufang ZHANG, Linhai ZHONG, Shizhen WU
Abstract(525) PDF(107)
Research Progress on Mechanism and Imaging Evaluation of In-Stent Restenosis After PCI
Li ZHANG, Qinhong LI, Jiangli LI, Wenjuan SHEN, Zhuo YU, Peng CHEN
Abstract(1763) PDF(117)
Articles in press have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
Display Method:
Immunopathogenesis of Lichen Planus
Rongyu YANG, Zehua HAN, Xiaotong LIU, Rong LI, Junli HE, Yingying XIANG
 doi: 10.12259/j.issn.2095-610X.S20261017
Abstract(67) HTML PDF(0)
Mechanism of Ginsenoside Rg1 in Alleviating Alcohol-induced Liver Injury in Tree Shrews via Activating of Nrf2 Pathway and Inhibiting of Mitochondrial Apoptosis
Jintao LI, Tianyong XU, Yanli HU, Yuexin HU, Shengxiong HONG, Yu LU, Jishuai CHENG, Li XU
 doi: 10.12259/j.issn.2095-610X.S20261002
Abstract(35) HTML PDF(0)
Memory Reconsolidation and Intervention in Drug Addiction
Wen ZHANG, Huawei WANG, Mei ZHU
 doi: 10.12259/j.issn.2095-610X.S20261001
Abstract(132) HTML PDF(3)
Panax Notoginseng Saponins-induced Autophagy-mediated Microglial Polarization via Activation of the AMPK Signaling Pathway and Its Effects on Neurons in A Cellular Model of Neuropathic Pain
Ying TAN, Wendong CHEN, Lanqing PU, Kun YANG, Ziting REN, Jun WANG, Haixia JIANG
Abstract(115) PDF(1)
Discriminative Performance of the Combined MoCA/MMSE and NPAR for Type 2 Diabetes Mellitus-related Peripheral Neuropathy
Yanzhen ZHANG, Li SHI, Lingyan YUAN, Hongying NIU, Peixin TIAN, Yushan XU
Abstract(153) PDF(0)
M-CSF Mediates Macrophage Polarization to Regulate Chondrocyte Function in Osteoarthritis via the CSF1R/NF-κB Signaling Pathway
Bin CAO, Baojun LI, Gaisheng HE, Kang YANG, Yini MAO, Lei TANG
Abstract(120) PDF(0)
Expression of PSMB5 in Bladder Urothelial Carcinoma and Its Clinicopathological Significance
Runlin FENG, Yanping TAO, Ziran MA
Abstract(100) PDF(1)
Spatio-temporal Characteristics of Early Gait Abnormalities in AD Model Mice Induced by Acute Intracerebroventricular Injection of Aβ1-42
Yunuo WANG, Fuquan SHU, Lingyi HU, Quanzhu ZHOU, Chenhao ZHOU, Minrong YANG, Yu SUN, Kaixuan LUO
Abstract(100) PDF(2)
Mechanisms of Tianlongjie in the Treatment of Idiopathic Pulmonary Fibrosis Using Network Pharmacology Combined with Machine Learning
Haiqing JING, Chunyan YANG, Jie LIU, Bin CHEN, Yanrui WU, Ting SU, Yi FU
Abstract(142) PDF(4)
Identifying Adverse Event Signals and Risk Analysis of Semaglutide Based on the FAERS Database
Zhuo ZHU, Hong XU, Hongying XIA, Feilong TAN
Abstract(153) PDF(4)
Construction of A Predictive Model for Multidrug-resistant Organisms Carriage in HIV/AIDS Patients
Jingjing XU, Jiawei XIA, Le ZHANG, Xiao LU, Li LIU, Haiwen LI
Abstract(440) PDF(42)
Value of LASSO-Logistic Regression Model Incorporating CT Features and GLCM Parameters in Differentiating Benign and Malignant Solitary Pulmonary Nodules
Sheng GAO, Xingxing ZHAN
Abstract(480) PDF(44)
ALOX15B-GPX4 Axis Alleviates Depression by Regulating Neuroinflammation and Ferroptosis
Shu'e ZENG, Zhixing LU, Yanjun WANG, Tian MENG, Ruina LIU
Abstract(539) PDF(84)
Relationship Between Serum Apelin-13，Gal-3，sLOX-1 and Early Neurological Deterioration in Elderly Patients with Acute Ischemic Stroke and Their Predictive Significance
Zhiming YAO, Biwen ZENG, Guoming WANG
Abstract(594) PDF(103)
A Study on the Impact of Catching Growth Rate on Neuropsychological Development in Premature Infants
Manman LI, Di ZHANG, Lihua LI
Abstract(680) PDF(107)
The Relationship between Serum CTRP7 and CTRP15 Levels and Insulin Resistance and Maternal and Neonatal Outcomes in Patients with Gestational Diabetes Mellitus
Qiang JI, Yuan FANG, Ziping PENG
Abstract(464) PDF(117)
Construction and Validation of a Nomogram for Predicting the Risk of Delirium in Patients with Acute Exacerbation of COPD Complicated by Respiratory Failure
Yushan TANG, Liuhui ZHANG, Yang WAN
Abstract(550) PDF(84)
Construction and Validation of a Predictive Model of Serum miR-30d-5p，miR-146a-5p，and Treg/Th17 Ratio for Predicting 90-day Prognosis in Elderly Patients with Sepsis
Guangyun HU, Lingling WANG
Abstract(572) PDF(87)
Risk Factor Analysis and Predictive Model Construction for Thrombohemorrhagic Events in Patients with Acute Promyelocytic Leukemia
Juan QIU, Xuan HE
Abstract(646) PDF(97)
Prognostic Value of Soluble Growth Stimulating Express Gene 2 Protein and Growth Hormone/Insulin-like Growth Factor in Peripheral Blood for Prostate Cancer
Yu WANG, Zhanfang GUO, Zhen ZHANG, Cunyuan DONG
Abstract(550) PDF(104)
Predictive Value of TILs and SLC35A2 Expression in Tumor Microenvironment for Neoadjuvant Therapy Response in Breast Cancer
Xinhua LI, Kejiao WU, Jiamin WU
Abstract(545) PDF(114)
Risk Factors for Catheter-related Fungal Infections in Burn Patients and Their Correlation with TLR4 and NF-κB
Juanru HE, Yani ZHANG, Xiaochun JIAO, Yanning SI, Qin ZHOU
Abstract(482) PDF(116)
Mechanisms of miR-448-mediated Inhibition of Malignant Behaviors in Gastric Cancer Cells Through Downregulation of ADAM10 Expression
Xiuqiong YANG, Liping AI, Jiahao LUO, Jiamiao LI, Xianmin HUANG, Mengyang MA, Xiaosong HUANG, Xuesong WU
Abstract(547) PDF(122)
Value of Next-generation Sequencing Combined with GeneXpert MTB/RIF in Early Diagnosis of Tuberculous Meningitis
Le ZHANG, Jiawei XIA, Depan CHEN, Haiwen LI, Bin BAI, Yatao YANG, Xiang LI, Kaiyi ZHANG
Abstract(669) PDF(113)
Predictive Value of Nomogram Model Based on Clinicopathological Factors and Radiomics in Predicting Mortality Risk of Death in Elderly Patients with Advanced Non-small Cell Lung Cancer
Yinghu WANG, Qiang WANG, Yanshan MA, Zhitao XU, Meiyan NIU
Abstract(765) PDF(108)
Expression Levels of Serum RAGE and CXCL10 in Children with Bronchiolitis and Their Correlation with Disease Severity
Weina WANG, Wenlu HAN, Yun DU, Shuai GAO
Abstract(423) PDF(108)
Interactive Effects and Predictive Performace of IL-19 and miR-320 on In-stent Restenosis After PCI in Patients with Type 2 Diabetes Mellitus Complicated with NSTEMI
Kai YANG, Shangming WANG, Hailiang XIONG, Yonggang CHEN
Abstract(624) PDF(96)
Association of Plasma EPB41L3 Gene Expression and Methylation with the Risk of Developing Colorectal Cancer
Zhixin GENG, Shenjian XU
Abstract(555) PDF(93)
Ganoderma Lucidum Polysaccharides Ameliorate Symptoms in Rats with Rheumatoid Arthritis by Modulating Macrophage Polarization via the MAPK/NF-κB/IL-6 Pathway
Yun CAO, Rong LIU, Yan WU
Abstract(876) PDF(109)
Exploration of a Prediction Model for Delay Onset of Lactation Stage II in Cesarean Section Parturients
Minrong MA, Ling LI, Juan LI, Zhiqiong ZOU, Danning ZHANG, Juyu ZHANG
Abstract(746) PDF(93)
A Comparative Study of Developmental Trajectories in Term ART and Spontaneously Conceived Infants During Infancy: A Multicenter Investigation Using the Denver Developmental Screening Test
Xiufang LI, Xiaoxia WANG, Tong ZHU, Mengxin LV, Tian HUANG
Abstract(759) PDF(127)
The Role and Mechanism of Mitochondrial Ferroptosis in Uremic Toxin-associated Myocardial Injury
Yaping ZHOU, Fangfang DI, Wei WANG
Abstract(1145) PDF(222)
Research Progress on Bacteriophage Prevention and Treatment of Dental Caries
Zehua HAN, Xiaoyan YANG, Yuliang CHEN, Xuelin LI, Rongyu YANG, Yingying XIANG
Abstract(907) PDF(181)
Molecular Mechanism of the YAP1/ANXA2 Signaling Axis in Regulating Apoptosis and Migration of Renal Tubular Epithelial Cells
Shaoting SUN, Lanmei LI, Weiwei BAI, Na CHEN, Meng WANG, Ming ZHANG, Yafen LI
Abstract(1131) PDF(175)
Research Advances in D-dimer/Fibrinogen Ratio and Fibrinogen/Albumin Ratio in Acute Coronary Syndromes
Jizhou LI, Hongwei LI, Ye ZHANG, Hongling YANG
Abstract(1231) PDF(174)
Risk Factors and Drug Resistance Analysis of Central Venous Catheter-related Fungal Infections in Maintenance Hemodialysis Patients
Gai WANG, Qianfang CHEN, Jianna ZHANG, Fuling YAN, Xiaoqian YU, Yajuan LI
Abstract(505) PDF(37)
The Clinical Screening Value of Peripheral Blood NETs Combined with Salivary Gland Ultrasound Score for Primary Sjögren's Syndrome
Miaomiao DING, Hongling LIU, Hong WEI
Abstract(566) PDF(43)
Predictive Value of FORCE Open Source CT Dual-energy Imaging in Preoperative Lymph Node Metastasis of Resectable Colon Cancer
Li YANG, Yu CHEN, Longxiangfeng HU, Mengyu XIE
Abstract(641) PDF(39)
Efficacy of Butylphthalide Combined with Atorvastatin in the Treatment of Cerebral Infarction and Its Effects on the Expression of vWF，PAI-1 and Ve Cadherin in Vascular Endothelium
Kejiao LI, Zichen LIU, Sha CHANG, Xue SONG, Fang LI
Abstract(1474) PDF(144)
Expert Consensus on the Diagnosis and Treatment of Chronic Coronary Syndrome with Traditional Chinese and Western Medicine in Yunnan Province
Li ZHANG, Ying ZHANG, Xueya ZHANG, Zhuo YU
Abstract(1884) PDF(164)
Column
Expert Forum
Research Progress on Quality of Life among Ethnic Minority Populations in Yunnan Province
Hai LAN, Hanwen ZHANG, Ziyao XU, Ruike XU, Haoshuang ZHAO, Chuanzhi XU
2026, 47(9): 1-18.    doi: 10.12259/j.issn.2095-610X.S20260901
Abstract(2308) HTML PDF(10)
Reviews
Progress on Resistance Mechanisms of Heterogeneous Vancomycin-Intermediate Staphylococcus aureus
Jiaxian LI, Juan DU, Xiyue LIN, Fukai BAO, Zhen LI, Dehua LIU
2026, 47(9): 19-32.    doi: 10.12259/j.issn.2095-610X.S20260902
Abstract(1624) HTML PDF(19)
Advances in the Diagnosis and Treatment of Postoperative Meningitis in Neurosurgery
Shaobo SHI, Qianzheng SU, Jinyong LONG, Liming FENG, Xiaobin XU, Huatao NIU
2026, 47(9): 33-45.    doi: 10.12259/j.issn.2095-610X.S20260903
Abstract(2293) HTML PDF(130)
Original Articles Basic of Medicine
ATF4/TRIB3 Pathway Regulating Hippocampal Neuronal Injury and Mitochondrial Unfolded Protein Response in Epilepsy
Yao MA, Guohui ZU, Jiarong LIU, Haifeng ZHANG, Lu LING, Xue HAN
2026, 47(9): 46-53.    doi: 10.12259/j.issn.2095-610X.S20260904
Abstract(2454) HTML PDF(140)
Evaluation of the Anti-tumor Activity of PD-1/PD-L1 Inhibitors Combined with Cisplatin Based on a Jurkat and Lung Cancer Cell Co-culture Model
Yanglin DENG, Pan LI, Lisha BI, Wenjie LU, Yani MA
2026, 47(9): 54-66.    doi: 10.12259/j.issn.2095-610X.S20260905
Abstract(894) HTML PDF(132)
Propofol Modulates the miR-142-3p/RAC1/NF-κB Axis to Influence Knee Osteoarthritis in Rats
Chengneng FAN, Jintao SHI, Shuangwei LU, Meng YU
2026, 47(9): 67-77.    doi: 10.12259/j.issn.2095-610X.S20260906
Abstract(2373) HTML PDF(202)
Effects of Dexmedetomidine Combined with Sufentanil on Pain Sensitization and Spinal Inflammatory Response in Rats with Incisional Pain
Huizhen GAO, Qingling YANG, Yanan ZHANG, Shujun GAO
2026, 47(9): 78-88.    doi: 10.12259/j.issn.2095-610X.S20260907
Abstract(939) HTML PDF(206)
Clinical Research
Establishment of a Nomogram Model for Predicting Abnormal Bone Mass in Diabetic Patients
Hui LIU, Xinyi PENG, Tonger LIANG, Yong ZHAO
2026, 47(9): 89-96.    doi: 10.12259/j.issn.2095-610X.S20260908
Abstract(2446) HTML PDF(187)
Awareness of the Core Knowledge of Cancer Prevention and Control in Ethnic Minority Areas of Yunnan，China: A Cross-Sectional Study
Hai ZHOU, Jun HE, Fengjian SA, Sile LI, Yongcun CEN, Jie MA, Yunchao HUANG
2026, 47(9): 97-105.    doi: 10.12259/j.issn.2095-610X.S20260909
Abstract(3217) HTML PDF(206)
Study on the Distribution Characteristics of Coronal Plane Alignment of the Knee （CPAK） Classification in Patients with Knee Osteoarthritis and Healthy Individuals in Yunnan，China
Jia CHENG, Anli ZHOU, Zhihang SUN, Hao TANG, Wenjin LI, Ning LU
2026, 47(9): 106-121.    doi: 10.12259/j.issn.2095-610X.S20260910
Abstract(2230) HTML PDF(107)
Risk Factors Associated with Recurrence in Patients after Endoscopic Gastrointestinal Polypectomy and the Intervention Effect of the Informatized Hierarchical Management Model
Cui MA, Qianjing ZHENG, Lijun WU, Yan NIE
2026, 47(9): 122-130.    doi: 10.12259/j.issn.2095-610X.S20260911
Abstract(939) HTML PDF(132)
Analysis of the Correlation between miR-125b-5p，Cardiac Function，and Myocardial Injury in Patients with HFpEF
Lu CHEN, Na PANG, Huijing ZHANG, Meng'en ZHAI
2026, 47(9): 131-139.    doi: 10.12259/j.issn.2095-610X.S20260912
Abstract(2452) HTML PDF(45)
Manual Therapy Combined with Rehabilitation Training Accelerates Recovery after Knee Replacement
Meihua CHEN, Shaodong XIE, Deming ZENG, Yaodong CHEN, Shiyun LUO, Shaoyun WANG, Shaoyi HUANG
2026, 47(9): 140-150.    doi: 10.12259/j.issn.2095-610X.S20260913
Abstract(615) HTML PDF(44)
Genetic Variant Analysis in 10 Patients with Polycystic Kidney Disease
Zaihui ZHANG, YuanYuan LV, Zhihong WANG
2026, 47(9): 151-158.    doi: 10.12259/j.issn.2095-610X.S20260914
Abstract(565) HTML PDF(110)
Correlation and Predictive Value of Serum Chemerin，SDF-1α，and MiR-21 with Adjacent Vertebral Re-fracture after Thoracolumbar Fracture Surgery in Elderly Patients
Yongzhan ZHANG, Haoyang LI, Liqiang YIN
2026, 47(9): 159-167.    doi: 10.12259/j.issn.2095-610X.S20260915
Abstract(690) HTML PDF(126)
Teaching Research
A Study on the Combination of BOPPPS Model and TBL in Cultivating Critical Thinking of Undergraduate Nursing Students
Xuping ZHANG, Chen ZHANG, Yunxiang YAN, Dan YANG, Wei LIU
2026, 47(9): 168-176.    doi: 10.12259/j.issn.2095-610X.S20260916
Abstract(1010) HTML PDF(115)

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