Effect of HIV Post-exposure Prophylaxis in Kunming City in 2019

Bo TIAN; Jun LIU; Chong-xi LI; Rong HE; Shan-qun GU; Wei-bo WANG

doi:10.12259/j.issn.2095-610X.S20210721

Volume 42 Issue 7

Jul. 2021

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Bo TIAN, Jun LIU, Chong-xi LI, Rong HE, Shan-qun GU, Wei-bo WANG. Effect of HIV Post-exposure Prophylaxis in Kunming City in 2019[J]. Journal of Kunming Medical University, 2021, 42(7): 126-129. doi: 10.12259/j.issn.2095-610X.S20210721

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Effect of HIV Post-exposure Prophylaxis in Kunming City in 2019

doi: 10.12259/j.issn.2095-610X.S20210721

Infection 1 Department of The Third People’s Hospital of Kunming Kunming Yunnan，650041，China

Received Date: 2021-04-23
Available Online: 2021-07-19
Publish Date: 2021-07-21

Abstract

Abstract

Objective To understand the treatment status and effect of HIV post-exposure prophylaxis in Kunming city in 2019. The proportion of the 28-day course completed and the influencing factors. It provides a reference for the wide application of HIV post-exposure prophylaxis. Methods Descriptive analysis was carried out on the data of HIV post-exposure prophylaxis in kunming city in 2019. Logistic analysis of factors affecting the completion of 28 days of treatment. Results The average age of 872 patients of HIV post-exposure prophylaxis was 32 （26, 36） years. Men accounted for 81.99%. Only 10.09% of people identified the infection source person with HIV. The proportion of patients with treatment FTC + DTG/RAL was 78.56%. The proportion of patients within 2 h was 2.87%, the proportion of patients within 2 h to 24 h was 63.88%. 78.56% completed the 28-day course. Unemployed, inactive and student patients were less likely to complete the 28-day course （OR = 1.668, P = 0.012）; It is clear that patients who knew the infection source person with HIV infection are more likely to complete a 28-day course of treatment （OR = 0.166, P < 0.001）. Only one of the 544 people who had test results or called then tested positive for HIV. Conclusion HIV post-exposure prophylaxis treatment is predominantly male, most do not know if the infection source person with HIV. Increasing economic income and identifying infection status are beneficial to increasing drug completion rate. At the same time, publicity and education should be strenghened to improve the timeliness and effectiveness of medical treatment.
- HIV,
- Exposure,
- Prevention,
- Blockade

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