Volume 42 Issue 9
Sep.  2021
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Bin YANG, Ni-ni TIAN, Juan MA. The Guiding Effect of FFR in Interventional Treatment of Multivessel Coronary Artery Disease and the Impact on Adverse Event[J]. Journal of Kunming Medical University, 2021, 42(9): 90-94. doi: 10.12259/j.issn.2095-610X.S20210930
Citation: Bin YANG, Ni-ni TIAN, Juan MA. The Guiding Effect of FFR in Interventional Treatment of Multivessel Coronary Artery Disease and the Impact on Adverse Event[J]. Journal of Kunming Medical University, 2021, 42(9): 90-94. doi: 10.12259/j.issn.2095-610X.S20210930

The Guiding Effect of FFR in Interventional Treatment of Multivessel Coronary Artery Disease and the Impact on Adverse Event

doi: 10.12259/j.issn.2095-610X.S20210930
  • Received Date: 2021-07-18
    Available Online: 2021-09-13
  • Publish Date: 2021-09-30
  •   Objective  To investigate the effect of percutaneous coronary intervention (PCI) under the guidance of FFR on the guidance of patients with the acute coronary syndrome (ACS) with multi-vessel disease and the effect on adverse events.   Methods  A total of 320 patients with ACS complicated with multi-vessel disease admitted to the Department of Cardiology, of the First People’ s Hospital of Kunming city from April 2019 to April 2020 were divided into 2 groups by random number table method, with 160 patients in each group. PCI was guided by blood flow reserve fraction (FFR group) and PCI was guided by coronary angiography (CAG group). The differences in the basic data, success rate of PCI and the number of stent implantation between the two groups were compared. The incidence of major adverse cardiovascular events (MACE) was compared between the two groups after 6 months of the follow-up.   Results  There was no significant difference in the basic data between the two groups (P > 0.05); There was no statistical significance in the success rate of PCI, duration of PCI operation and length of hospital stay between 2 groups (P > 0.05); The number of stent implanted and the amount of contrast agent used in FFR group were lower than those in CAG group (P < 0.05); 6 months after the surgery, there was no significant difference in the total incidence of target vessel revascularization and adverse cardiovascular events between the two groups (P > 0.05).   Conclusion  Downward PCI guided by FFR can reduce the unnecessary stent implantation, reduce the occurrence of major adverse cardiovascular events, and improve the prognosis of patients with ACS complicated with multi-vessel disease.
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