Volume 42 Issue 9
Sep.  2021
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Bin YANG, Ni-ni TIAN, Juan MA. The Guiding Effect of FFR in Interventional Treatment of Multivessel Coronary Artery Disease and the Impact on Adverse Event[J]. Journal of Kunming Medical University, 2021, 42(9): 90-94. doi: 10.12259/j.issn.2095-610X.S20210930
Citation: Bin YANG, Ni-ni TIAN, Juan MA. The Guiding Effect of FFR in Interventional Treatment of Multivessel Coronary Artery Disease and the Impact on Adverse Event[J]. Journal of Kunming Medical University, 2021, 42(9): 90-94. doi: 10.12259/j.issn.2095-610X.S20210930

The Guiding Effect of FFR in Interventional Treatment of Multivessel Coronary Artery Disease and the Impact on Adverse Event

doi: 10.12259/j.issn.2095-610X.S20210930
  • Received Date: 2021-07-18
    Available Online: 2021-09-13
  • Publish Date: 2021-09-30
  •   Objective  To investigate the effect of percutaneous coronary intervention (PCI) under the guidance of FFR on the guidance of patients with the acute coronary syndrome (ACS) with multi-vessel disease and the effect on adverse events.   Methods  A total of 320 patients with ACS complicated with multi-vessel disease admitted to the Department of Cardiology, of the First People’ s Hospital of Kunming city from April 2019 to April 2020 were divided into 2 groups by random number table method, with 160 patients in each group. PCI was guided by blood flow reserve fraction (FFR group) and PCI was guided by coronary angiography (CAG group). The differences in the basic data, success rate of PCI and the number of stent implantation between the two groups were compared. The incidence of major adverse cardiovascular events (MACE) was compared between the two groups after 6 months of the follow-up.   Results  There was no significant difference in the basic data between the two groups (P > 0.05); There was no statistical significance in the success rate of PCI, duration of PCI operation and length of hospital stay between 2 groups (P > 0.05); The number of stent implanted and the amount of contrast agent used in FFR group were lower than those in CAG group (P < 0.05); 6 months after the surgery, there was no significant difference in the total incidence of target vessel revascularization and adverse cardiovascular events between the two groups (P > 0.05).   Conclusion  Downward PCI guided by FFR can reduce the unnecessary stent implantation, reduce the occurrence of major adverse cardiovascular events, and improve the prognosis of patients with ACS complicated with multi-vessel disease.
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  • [1]
    杨巧妮,谢学建,梁田. 血流储备分数指导下分期PCI干预非梗死相关动脉对STEMI患者短期预后的影响[J]. 临床心血管病杂志,2019,35(3):259-263.
    [2]
    罗林萍,刘明艳,吴翔,等. 急性心肌梗死心电图变化与冠脉造影结果的相关性[J]. 昆明医科大学学报,2017,38(1):113-116. doi: 10.3969/j.issn.1003-4706.2017.01.025
    [3]
    谢志艺,陈建东. 冠状动脉造影无明显狭窄心肌缺血患者72例临床分析[J]. 基层医学论坛,2017,21(22):2894-2896.
    [4]
    李梦梦,玉献鹏,杨帮国,等. 基于冠状动脉CT造影的无创血流储备分数在冠心病诊断中应用的初探[J]. 心肺血管病杂志,2017,36(8):685-691. doi: 10.3969/j.issn.1007-5062.2017.08.020
    [5]
    杨琳,徐磊,何继强,等. 基于CT的冠状动脉血流储备分数对冠状动脉含钙化病变的诊断评价[J]. 中华放射学杂志,2019,53(8):698-704.
    [6]
    《中国冠状动脉血流储备分数测定技术临床路径专家共识》专家组. 中国冠状动脉血流储备分数测定技术临床路径专家共识[J]. 中国介入心脏病学杂志,2019,27(3):121-133.
    [7]
    毕月,李拥军. 冠状动脉钙化病变机制及治疗相关的研究进展[J]. 临床荟萃,2020,35(7):653-656. doi: 10.3969/j.issn.1004-583X.2020.07.015
    [8]
    陈炜佳,姚康,李晨光,等. CZT-SPECT测定的冠状动脉血流储备对诊断冠心病的增益价值[J]. 中华核医学与分子影像杂志,2019,39(12):714-719. doi: 10.3760/cma.j.issn.2095-2848.2019.12.003
    [9]
    陈珊珊,韩明华. 血流储备分数在冠状动脉介入治疗中的应用研究[J]. 重庆医学,2017,46(20):2837-2839. doi: 10.3969/j.issn.1671-8348.2017.20.034
    [10]
    任雪会,崔胜宏,马秀梅,等. 多层螺旋CT血管造影在评价冠状动脉粥样硬化性心脏病心肌缺血程度价值分析[J]. 中国CT和MRI杂志,2021,19(4):30-32. doi: 10.3969/j.issn.1672-5131.2021.04.010
    [11]
    Warren J,Nanayakkara S,N Andrianopoulos,et al. Impact of pre-procedural blood pressure on long-term outcomes following percutaneous coronary intervention[J]. Journal of the American College of Cardiology,2019,73(22):2846-2855. doi: 10.1016/j.jacc.2019.03.493
    [12]
    王晓腾,王海曙,宋安,等. PCI后FFR值对冠状动脉中度狭窄患者主要心脏不良事件发生的预测价值[J]. 精准医学杂志,2020,35(2):142-145,149.
    [13]
    张湘敏,吕梁,刘兴利,等. 常规CCTA联合CT无创血流储备分数对冠状动脉病变诊断价值的Meta分析[J]. 临床心血管病杂志,2019,35(10):940-946.
    [14]
    Gunn J,Taggart D P. Transcatheter versus surgical intervention:Lessons from trials of coronary revascularisation[J]. Heart (British Cardiac Society),2019,105(Suppl 2):s44-s49.
    [15]
    陆志锋,陈晞明,王世祥. 不同血流储备分数冠状动脉临界病变的血管内超声特征研究[J]. 临床心血管病杂志,2019,35(12):1093-1097.
    [16]
    陈道虎,刘辉,何书武,等. "分站式"杂交血运重建技术对多支冠状动脉病变患者cTnT、血流动力学和预后的影响[J]. 安徽医科大学学报,2019,54(7):1127-1131.
    [17]
    Mey J D,Bloksgaard M,C Aalkjær. Physiological consequences of coronary arteriolar dysfunction and its influence on cardiovascular disease:Diagnostic and additional therapeutic consequences[J]. Physiology,2019,34(2):82-83. doi: 10.1152/physiol.00053.2018
    [18]
    宋荟芬,李红,李响,等. 血流储备分数与冠状动脉造影指导的治疗对急性冠状动脉综合征患者冠状动脉中度狭窄病变预后的影响[J]. 中国介入心脏病学杂志,2016,24(4):186-190. doi: 10.3969/j.issn.1004-8812.2016.04.002
    [19]
    张香玲,孙喆,李永辉,等. 替格瑞洛对经皮冠状动脉介入治疗老年急性ST段抬高型心肌梗死患者的疗效及安全性[J]. 中华老年医学杂志,2020,39(3):277-281. doi: 10.3760/cma.j.issn.0254-9026.2020.03.007
    [20]
    刘志远,张金盈,刘江波,等. 冠脉内注射重组人尿激酶原溶栓联合PCI对急性心肌梗死患者冠脉血流水平、无复流发生率及预后的影响[J]. 重庆医科大学学报,2020,45(4):510-516.
    [21]
    Nandi A,Pal P,Basu S. A comparison of serum IL6 and CRP levels with respect to coronary changes and treatment response in Kawasaki disease patients:A prospective study[J]. Rheumatology International,2019,39(10):1797-1801. doi: 10.1007/s00296-019-04375-9
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