The Effect of 1800 MHz Radio Frequency Electromagnetic Field Exposure on the Expression of GFAP，NCAM and GABA Receptors in Hippocampus of Rats

Sheng-qingyu ZHANG; Xiao SHU; Xi-nan WU; Zhi-qiang LI; Hui-xin WU; Yuan ZHANG; Yu-rong JIANG; Shi-jia YANG; Yun-zhen MU

doi:10.12259/j.issn.2095-610X.S20210939

Volume 42 Issue 9

Sep. 2021

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Article Navigation > Journal of Kunming Medical University > 2021 > 42(9): 13-19

Sheng-qingyu ZHANG, Xiao SHU, Xi-nan WU, Zhi-qiang LI, Hui-xin WU, Yuan ZHANG, Yu-rong JIANG, Shi-jia YANG, Yun-zhen MU. The Effect of 1800 MHz Radio Frequency Electromagnetic Field Exposure on the Expression of GFAP，NCAM and GABA Receptors in Hippocampus of Rats[J]. Journal of Kunming Medical University, 2021, 42(9): 13-19. doi: 10.12259/j.issn.2095-610X.S20210939

Citation:

Sheng-qingyu ZHANG, Xiao SHU, Xi-nan WU, Zhi-qiang LI, Hui-xin WU, Yuan ZHANG, Yu-rong JIANG, Shi-jia YANG, Yun-zhen MU. The Effect of 1800 MHz Radio Frequency Electromagnetic Field Exposure on the Expression of GFAP，NCAM and GABA Receptors in Hippocampus of Rats[J]. Journal of Kunming Medical University, 2021, 42(9): 13-19. doi: 10.12259/j.issn.2095-610X.S20210939

Citation:

Sheng-qingyu ZHANG, Xiao SHU, Xi-nan WU, Zhi-qiang LI, Hui-xin WU, Yuan ZHANG, Yu-rong JIANG, Shi-jia YANG, Yun-zhen MU. The Effect of 1800 MHz Radio Frequency Electromagnetic Field Exposure on the Expression of GFAP，NCAM and GABA Receptors in Hippocampus of Rats[J]. Journal of Kunming Medical University, 2021, 42(9): 13-19. doi: 10.12259/j.issn.2095-610X.S20210939

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The Effect of 1800 MHz Radio Frequency Electromagnetic Field Exposure on the Expression of GFAP，NCAM and GABA Receptors in Hippocampus of Rats

doi: 10.12259/j.issn.2095-610X.S20210939

1.
School of PublIc Health
2.
Graduate Faculty
3.
Biomedical Engineering Research Center
4.
School of Basic Medicine，Kunming Medical University，Kunming Yunnan 650500，China

Received Date: 2021-07-05
Publish Date: 2021-09-25

Abstract

Abstract

Objective To explore the effects of 1800 MHz radio frequency electromagnetic fields on the body weight and expression of Glial fibrillary acidic protein （GFAP）, Neural Cell Adhesion Molecule （NCAM） and Gamma-Amino Butyric Acid （GABA） receptors in hippocampus of rats. Methods 14 SD rats were divided into the exposure group and the control group and the ratio of male to female was 3∶4 in the exposure group and 4∶3 in the control group. Exposure frequency 1800 MHz, intensity of 0.5 mW/cm² RF field. Systemic exposure to three weeks, 12 hours a day （20:00-08:00）. After the exposure, the rats in the two groups were weighed respectively. Immunohistochemical techniques hippocampus GFAP stained sections, and GFAP NCAM and GABA receptors expression was measured in the hippocampus CA1, CA3 and DG （dentate gyrus）regions. Results The exposure group and the control group showed no significant difference in the body weight （P > 0.05）; the expression of GFAP in the CA1 and DG areas of the hippocampus decreased （ P < 0.05）, and there was no statistical significance in the other groups （ P > 0.05）. Conclusion At a frequency of 1800 MHz, an intensity of 0.5 mW/cm² RF electromagnetic field SD rats are exposed for 3 weeks in rat hippocampal CA1 region and DG GFAP expression decreased, which may affect certain brain diseases.
- Radiofrequency electromagnetic field,
- Physiological growth,
- Hippocampus

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