Effect of <i>Trillium tschonoskii</i> Maxim. on the Contraction of Uterine Smooth Muscle

Xiao-zhen WANG; Lu LIU; An-chao WU; Yue-han WANG; Zhi-hong ZHOU; Zhu-ya YANG

doi:10.12259/j.issn.2095-610X.S20211102

Volume 42 Issue 11

Nov. 2021

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Article Navigation > Journal of Kunming Medical University > 2021 > 42(11): 9-13

Xiao-zhen WANG, Lu LIU, An-chao WU, Yue-han WANG, Zhi-hong ZHOU, Zhu-ya YANG. Effect of Trillium tschonoskii Maxim. on the Contraction of Uterine Smooth Muscle[J]. Journal of Kunming Medical University, 2021, 42(11): 9-13. doi: 10.12259/j.issn.2095-610X.S20211102

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Xiao-zhen WANG, Lu LIU, An-chao WU, Yue-han WANG, Zhi-hong ZHOU, Zhu-ya YANG. Effect of Trillium tschonoskii Maxim. on the Contraction of Uterine Smooth Muscle[J]. Journal of Kunming Medical University, 2021, 42(11): 9-13. doi: 10.12259/j.issn.2095-610X.S20211102

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Effect of Trillium tschonoskii Maxim. on the Contraction of Uterine Smooth Muscle

doi: 10.12259/j.issn.2095-610X.S20211102

Engineering Research Center for Chinese Herbal Pieces of Yunnan University of TCM，Kunming Yunnan 650500，China

Received Date: 2021-09-16
Available Online: 2021-11-15
Publish Date: 2021-11-30

Abstract

Abstract

Objective To study the chemical constituents of the rhizomes of Trillium tschonoskii that cause uterine smooth muscle contraction. Methods The isolated rat uterine smooth muscle test method was used to screen the activity of different extracted parts of Trillium tschonoskii. Modern spectroscopy techniques were used to identify the main components of the effective parts. Results The main active part of T.tschonoskii that caused uterine smooth muscle contraction was screened, and three main components were identified as pennogenin saponins from this part. Conclusion T.tschonoskii has the effect of inducing uterine smooth muscle contraction, and the main active ingredient of this effect was pennogenin saponins.
- Trillium tschonoskii,
- Uterine smooth muscle,
- Chemical composition,
- Pennogenin saponins

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