Correlation between Gestational Age, Biparietal Diameter and Fetal Thyroid Estimated by the 2-Dimensional Sonography

Xiu-ling LI; Xu-dong DONG; Huan-ling LIU; Fang YAN; Qing-sha HOU; Chun CHEN

doi:10.12259/j.issn.2095-610X.S20211108

Volume 42 Issue 11

Nov. 2021

Turn off MathJax

Article Contents

Article Navigation > Journal of Kunming Medical University > 2021 > 42(11): 45-50

Xiu-ling LI, Xu-dong DONG, Huan-ling LIU, Fang YAN, Qing-sha HOU, Chun CHEN. Correlation between Gestational Age, Biparietal Diameter and Fetal Thyroid Estimated by the 2-Dimensional Sonography[J]. Journal of Kunming Medical University, 2021, 42(11): 45-50. doi: 10.12259/j.issn.2095-610X.S20211108

Citation:

Xiu-ling LI, Xu-dong DONG, Huan-ling LIU, Fang YAN, Qing-sha HOU, Chun CHEN. Correlation between Gestational Age, Biparietal Diameter and Fetal Thyroid Estimated by the 2-Dimensional Sonography[J]. Journal of Kunming Medical University, 2021, 42(11): 45-50. doi: 10.12259/j.issn.2095-610X.S20211108

Citation:

Xiu-ling LI, Xu-dong DONG, Huan-ling LIU, Fang YAN, Qing-sha HOU, Chun CHEN. Correlation between Gestational Age, Biparietal Diameter and Fetal Thyroid Estimated by the 2-Dimensional Sonography[J]. Journal of Kunming Medical University, 2021, 42(11): 45-50. doi: 10.12259/j.issn.2095-610X.S20211108

PDF( 944 KB)

Correlation between Gestational Age, Biparietal Diameter and Fetal Thyroid Estimated by the 2-Dimensional Sonography

doi: 10.12259/j.issn.2095-610X.S20211108

Dept. of Obstetrics，the First People’s Hospital of Yunnan Province/Affiliated Hospital of Kunming University of Science and Technology，Kunming Yunnan 650032，China

Received Date: 2021-09-22
Available Online: 2021-11-15
Publish Date: 2021-11-30

Abstract

Abstract

Objective To explore the correlation between different gestational age, biparietal diameter and fetal thyroid size by transabdominal two-dimensional ultrasound, and to provide the normal reference range of fetal thyroid for clinical evaluation of fetal thyroid function. Methods The diameter, circumference and area of the fetal thyroid were measured for 740 healthy pregnant women at 20～38 weeks, the 5th, 50th and 95th percentile was calculated. The correlation between the fetal thyroid with gestational age and biparietal diameter was analyzed respectively. Results The reference range of the diameter, circumference and area of fetal thyroid at 20-38 weeks were obtained. We found the 5th, 50th and 95th percentiles increased with the gestational age, and showed a high correlation with gestational age （r = 0.909, 0.904 and 0.913, respectively）, which was statistically significant （P < 0.01）; And also increased with biparietal diameter, highly correlated with the biparietal diameter （r = 0.922, 0.914 and 0.916, respectively）, which was statistically significant （P < 0.01）. Conclusion In this study, we established the reference range of fetal thyroid according to different gestational ages and biparietal diameter, which is not only helpful to monitor the size of fetal thyroid at high risk for early detection of fetal goiter dysfunction, but also can assess the effect of intrauterine therapy on goiter fetuses by monitoring fetal thyroid size.
- Fetus thyroid,
- Goiter,
- 2-dimensional sonography,
- Prenatal diagnosis

FullText(HTML)

References(22)

References

[1]	Derakhshan A,Peeters R P,Taylor P N,et al. Association of maternal thyroid function with birthweight:a systematic review and individual-participant data meta-analysis[J]. The Lancet Diabetes & Endocrinology,2020,8(6):501-510.
[2]	Gietka-Czernel M,DeBska M,Kretowicz P,et al. Fetal thyroid in two-dimensional ultrasonography:nomograms according to gestational age and biparietal diameter[J]. Eur J Obstet Gynecol Reprod Biol,2012,162(2):131-138. doi: 10.1016/j.ejogrb.2012.02.013
[3]	Glendenning P. Management of thyroid dysfunction during pregnancy and postpartum:an endocrine society clinical practice guideline[J]. J Clin Endocrinol Metab,2012,8(4):2543-2565.
[4]	Iijima S. Current knowledge about the in utero and peripartum management of fetal goiter associated with maternal Graves' disease[J]. Eur J Obstet Gynecol Reprod Biol X,2019,5(3):1-7.
[5]	Abdi H,Amouzegar A,F Azizi. Antithyroid drugs[J]. Iran J Pharm Res,2019,18(Suppl1):1-12.
[6]	Sarkar S,Bischoff L. Management of hyperthyroidism during the preconception phase,pregnancy,and the postpartum period[J]. Semi Reprod Med,2016,34(6):317-322. doi: 10.1055/s-0036-1593489
[7]	Pearce EN. Management of thyrotoxicosis:preconception,pregnancy,and the postpartum period[J]. Endocr Pract,2019,25(1):62-68. doi: 10.4158/EP-2018-0356
[8]	董源芬,杨冬梅. 妊娠合并甲状腺功能减的研究进展[J]. 中国优生与遗传杂志,2014,22(2):134-135.
[9]	Min-Jung K,Yong-Hwa C,So-Young P,et al. Intra-amniotic thyroxine to treat fetal goiter[J]. Obstet Gynecol Sci,2016,59(1):66-70. doi: 10.5468/ogs.2016.59.1.66
[10]	Stagnaro-Green A,Abalovich M,Alexander E,et al. Guidelines of the American thyroid association for the diagnosis and management of thyroid disease during pregnancy and postpartum[J]. Thyroid,2011,21(10):1081-1125. doi: 10.1089/thy.2011.0087
[11]	任金河,邵明鹤,梁淑霞,等. 胎儿甲状腺肿大的产前超声研究[J]. 中国全科医学,2004,7(20):1475-1476. doi: 10.3969/j.issn.1007-9572.2004.20.009
[12]	刘彦英,钱隽,李谊,等. 胎儿甲状腺的超声检测及其临床意义[J]. 中国超声医学杂志,2014,4(30):350-352.
[13]	李丽雅,吕国荣,李敏,等. 二维和三维超声联合羊水相关激素测定评价胎儿甲状腺功能[J]. 中国超声医学杂志,2014,30(7):639-641.
[14]	Ceccaldi P F,Cohen S,Vuillard E,et al. Correlation between colored doppler echography of fetal thyroid goiters and histologic study[J]. Fetal Diagn Ther,2010,27(4):233-235. doi: 10.1159/000304269
[15]	Luton D,Gac I L,Vuillard E,et al. Management of Graves’ disease during pregnancy:the key role of fetal thyroid gland monitoring[J]. J Clin Endocrinol Metab,2005,90(11):6093-6098. doi: 10.1210/jc.2004-2555
[16]	Bromley B,Frigoletto F D,Cramer D,et al. The fetal thyroid:normal and abnormal sonographic measurements[J]. J Ultrasound Med,1992,11(1):25-28. doi: 10.7863/jum.1992.11.1.25
[17]	Ranzini A C,Ananth C V,Smulian J C,et al. Ultrasonography of the fetal thyroid. Nomograms based on biparietal diameter and gestational age[J]. J Ultrasound Med,2001,20(6):613-617. doi: 10.7863/jum.2001.20.6.613
[18]	Bernardes L S,Ruano R,Sapienza A D,et al. Nomograms of fetal thyroid measurements estimated by 2-dimensional sonography[J]. J Clin Ultrasound,2008,36(4):193-199. doi: 10.1002/jcu.20434
[19]	Barbosa R M,Andrade K C,Silveira C,et al. Ultrasound measurements of fetal thyroid:reference ranges from a cohort of low-risk pregnant women[J]. Bio Med Research International,2019,17(12):1-8.
[20]	Marin R C,Bello-Munoz J C,Martinez G V,et al. Use of 3-dimensional sonography for prenatal evaluation and follow-up of fetal goitrous hypothyroidism[J]. J Ultrasound Med,2010,29(9):1339-1343. doi: 10.7863/jum.2010.29.9.1339
[21]	Nath CA,Oyelese Y,Yeo L,et al. Three-dimensional sonography in the evaluation and management of fetal goiter[J]. Ultrasound Obstet Gynecol,2005,25(3):312-314. doi: 10.1002/uog.1863
[22]	李敏,李丽雅,吕国荣,等. 三维超声检测胎儿甲状腺体积[J]. 中国医学影像技术,2013,29(1):158-160.

Relative Articles(20)

Relative Articles

[1]	Fan MA, Xiaoxiao WU, Xilin CHU, Ying ZHANG. Pelvic Floor Tthree-dimensional Ultrasound Evaluating Postpartum Pelvic Floor Dysfunction in Elderly Parturient Women. Journal of Kunming Medical University, 2023, 44(6): 64-69. doi: 10.12259/j.issn.2095-610X.S20230616
[2]	Miao HUANG, Fei XU, Aitao YIN, Yongping LU, Jiao YIN, Ting LI. The Application Value of 2D Ultrasound Combined with SWE Technique in the Evaluation of Rectus Abdominis in Pregnant Women. Journal of Kunming Medical University, 2023, 44(9): 55-61. doi: 10.12259/j.issn.2095-610X.S20230917
[3]	Linkun TA, Yunyan LI, Youliang JIN, Fei XU, Yongping LU, Yanling HUANG. Application of Two-dimensional Ultrasonography Combined with Three-dimensional Ultrasonography in the Diagnosis of Fetal Cleft Lip and Palate. Journal of Kunming Medical University, 2023, 44(6): 76-80. doi: 10.12259/j.issn.2095-610X.S20230620
[4]	Han Xiao Na , Luo Xiao Mao . . Journal of Kunming Medical University, 2020, 41(07): 71-75.
[5]	Hu Shun Qin , Lu Xiao Ning , Song Xin Yan , Geng Li , Xu Jing , Chen Min , Li Nan . . Journal of Kunming Medical University, 2020, 41(02): 149-152.
[6]	Zhang Zong Mei , Chen Ting , Yang Cheng Gang , Wu Lin , Luo Dan , Liu Ying . . Journal of Kunming Medical University, 2019, 40(09): 83-88.
[7]	Tong Rui , Lu Li Juan , Lei Jun Hua , Chai Juan , Cao Jing , Cao Juan . . Journal of Kunming Medical University, 2019, 40(09): 77-82.
[8]	Hu Shun Qin , Lu Xiao Ning , Xu Jing , Tang Dan , Sun Qing , Liu Qi Yun . . Journal of Kunming Medical University, 2018, 39(12): 85-89.
[9]	Tong Rui , Lu Li Juan , Qin Zhan Xiong , Lei Jun Hua , Huang Xian , Chai Juan , Cao Jing . Compare and Contrast of the Diagnosis of Cerebral Malformation on 2D Ultrasonography, 3D Ultrasonography against MRI. Journal of Kunming Medical University, 2018, 39(08): 113-118.
[10]	Xu Rong . The Value of Detecting Paratracheal Lymph Nodes by Ultrasonography in Diagnosis of Autoimmune Thyroiditis. Journal of Kunming Medical University,
[11]	Ning Rong Ping . Prenatal Ultrasound Diagnosis and Misdiagnosis Analysis of Fetal Persistent Right Umbilical Vein. Journal of Kunming Medical University,
[12]	Zhang Hui . A Comparative Study of Ultrasound Elastography and Two-dimensional Ultrasound in Benign and Malignant Lesions of Liver. Journal of Kunming Medical University,
[13]	Li Jian . 超声弹性成像在甲状腺结节鉴别诊断中的临床价值. Journal of Kunming Medical University,
[14]	Zhang Tao . . Journal of Kunming Medical University,
[15]	Zhao Xing Yuan . . Journal of Kunming Medical University,
[16]	Lei Yu . . Journal of Kunming Medical University,
[17]	Dai Qing Li . . Journal of Kunming Medical University,
[18]	Nian Ying Hua . . Journal of Kunming Medical University,
[19]	Yang Hui . . Journal of Kunming Medical University,
[20]	Yang Jie . . Journal of Kunming Medical University,