Clinical Comparison of Biliary Iodine-125 Stent and Bare Metal Stent in Treatment of Bismuth Corlette III Cholangiocarcinoma Complicated with Obstructive Jaundice

Fei SONG; Yingying XIANG; Jiayin CHE; Hongyang LI; Wenyong XU; Lingxiao WEI; Ming HUANG

doi:10.12259/j.issn.2095-610X.S20221110

Volume 43 Issue 11

Nov. 2022

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Fei SONG, Yingying XIANG, Jiayin CHE, Hongyang LI, Wenyong XU, Lingxiao WEI, Ming HUANG. Clinical Comparison of Biliary Iodine-125 Stent and Bare Metal Stent in Treatment of Bismuth Corlette III Cholangiocarcinoma Complicated with Obstructive Jaundice[J]. Journal of Kunming Medical University, 2022, 43(11): 85-89. doi: 10.12259/j.issn.2095-610X.S20221110

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Clinical Comparison of Biliary Iodine-125 Stent and Bare Metal Stent in Treatment of Bismuth Corlette III Cholangiocarcinoma Complicated with Obstructive Jaundice

doi: 10.12259/j.issn.2095-610X.S20221110

1.
Dept. of Invasive Intervention，The 3rd Affiliated Hospital of Kunming Medical University/ Yunnan Cancer Hospital，Kunming Yunnan 650118
2.
Dept. of Stomatology，Yan’an Hospital，Kunming Yunnan 650051
3.
Dept. of Hepatobiliary and Pancreatic Surgery， The 3rd Affiliated Hospital of Kunming Medical University/Yunnan Cancer Hospital，Kunming Yunnan 650118，China

Received Date: 2022-04-16
Publish Date: 2022-11-25

Abstract

Abstract

Objective To compare the efficacy of biliary ¹²⁵I seed stent and bare metal stent in the treatment of Bismuth Corlette Ⅲ cholangiocarcinoma complicated with obstructive jaundice. Methods A total of 51 patients with malignant biliary obstruction caused by Bismuth Corlette Ⅲ cholangiocarcinoma who were treated in our department from January 2010 to June 2018 were systematically retrospectively collected, of whom 25 were in the ¹²⁵I seed stent implantation group （observation group）. There were 26 cases in the bare metal stent implantation group （control group）, and the preoperative and postoperative liver function, complication rate, stent patency time and survival time were compared between the two groups. Results The liver function and jaundice degree of patients in the ¹²⁵I seed stent implantation group （observation group） and bare metal stent implantation group （control group） were significantly improved at 1 month after surgery. Compared with the control group, the observation group did not increase the incidence of postoperative complications. The average stent patency time in the observation group was （369.20±231.64） d, and the stent patency time was 310.05 d in the control group, the average stent patency time in the control group was （194.57±118.09） d, and the median stent patency time was 142.52 d. The stent patency time in the observation group was significantly longer than that in the control group （P＜0.05）. The median survival period was （334.24 ± 193.38） d, and the median survival period was 385.21 d. The average survival period of the control group was （251.23 ± 182.51） d, and the median survival period was 274.43 d. The survival period of patients in the observation group was significantly longer than that in the control group （P＜0.05）. Conclusion Compared with bare metal stent, biliary ¹²⁵I seed stent can significantly reduce stent restenosis rate, prolong stent patency time, and improve patient survival without increasing postoperative complications.
- Cholangiocarcinoma,
- ¹²⁵I seed stent,
- Bare metal stent,
- Malignant obstructive jaundice

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