Analysis on the Positive Test Results of Seven Joint Tests for Respiratory Pathogens in Hospitalized Children in Anning Area

Jianhong XU; Bingkun ZHANG; Aimin SHI; Qiong DU

doi:10.12259/j.issn.2095-610X.S20221118

Volume 43 Issue 11

Nov. 2022

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Article Navigation > Journal of Kunming Medical University > 2022 > 43(11): 141-145

Jianhong XU, Bingkun ZHANG, Aimin SHI, Qiong DU. Analysis on the Positive Test Results of Seven Joint Tests for Respiratory Pathogens in Hospitalized Children in Anning Area[J]. Journal of Kunming Medical University, 2022, 43(11): 141-145. doi: 10.12259/j.issn.2095-610X.S20221118

Citation:

Jianhong XU, Bingkun ZHANG, Aimin SHI, Qiong DU. Analysis on the Positive Test Results of Seven Joint Tests for Respiratory Pathogens in Hospitalized Children in Anning Area[J]. Journal of Kunming Medical University, 2022, 43(11): 141-145. doi: 10.12259/j.issn.2095-610X.S20221118

Citation:

Jianhong XU, Bingkun ZHANG, Aimin SHI, Qiong DU. Analysis on the Positive Test Results of Seven Joint Tests for Respiratory Pathogens in Hospitalized Children in Anning Area[J]. Journal of Kunming Medical University, 2022, 43(11): 141-145. doi: 10.12259/j.issn.2095-610X.S20221118

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Analysis on the Positive Test Results of Seven Joint Tests for Respiratory Pathogens in Hospitalized Children in Anning Area

doi: 10.12259/j.issn.2095-610X.S20221118

1.
Dept. of Pediatrics
2.
Hospital Office
3.
Laboratory，The First People’s Hospital of Anning; Kunming Yunnan 650300，China

Received Date: 2022-08-04
Available Online: 2022-10-28
Publish Date: 2022-11-14

Abstract

Abstract

Objective To analyze the positive test results of respiratory tract virus pathogens in hospitalized children in Anning area. Methods A total of 1766 hospitalized children in Anning District from September 2019 to February 2022 were selected as subjects, and they were divided into < 6 months old group, 6 months to 4 years old group, and 4 to 14 years old group according to their age. According to the prevention and control of COVID-19, the period from September 2019 to February 2020 shall be before public protection, and the period after February 2020 shall be after public protection. All children’s nasopharyngeal swab samples were tested by using direct immunofluorescence method for determination of antigen of influenza a virus, hepatitis b antigen of influenza virus, respiratory syncytial virus antigen and antigen of adenovirus, vice antigen of influenza virus type Ⅰ, parainfluenza Ⅱ antigen and deputy antigen of influenza virus type Ⅲ seven respiratory pathogens, and the data of children with respiratory tract pathogen examination were statistically analyzed. Results Among 1766 children, 584 （33.07%）were positive for respiratory virus pathogens. The main pathogens were respiratory syncytial virus （316 cases/17.89%）, adenovirus （90 cases/5.10%） and parainfluenza virus TYPE Ⅲ （82 cases/4.64%）. The positive rate of respiratory tract infection pathogen in children was mainly concentrated in < 6 months old group and 6 months to 4 years old group, with 111 （34.69%） and 327 （34.31%） cases, respectively. There was statistical significance in the positive rate of respiratory tract infection pathogens in different age groups （χ² = 8.392, P = 0.031）. The positive rate of influenza A virus detected after public protection （0.29%） was lower than that before public protection （5.94%）, the difference was statistically significant （P < 0.05）. There was no statistical significance in the detection rate of influenza B virus antigen, adenovirus antigen, parainfluenza virus Ⅰ, parainfluenza virus Ⅱ and parainfluenza virus Ⅱ before and after public protection （P > 0.05）. Conclusion The detection rate of virus etiology of respiratory tract infection in hospitalized children in Anning area is high, respiratory syncytial virus is the main pathogen, and the positive rate of influenza A virus detection decreases obviously after public protection, so it is important to continue to do public protection to prevent influenza A.
- Hospitalized children,
- Pathogens of respiratory tract infection,
- Detection results,
- Guiding value,
- Direct immunofluorescence

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