Analysis of Serum G-17 and PG Levels in Ethnic Minority Patients with Gastric Cancer in Lijiang Area

Xiaoji LI; Xuefang YANG; Qian LIU; Chongxiang HE; Yong YANG; Guorong LI

doi:10.12259/j.issn.2095-610X.S20230429

Volume 44 Issue 4

Apr. 2023

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Xiaoji LI, Xuefang YANG, Qian LIU, Chongxiang HE, Yong YANG, Guorong LI. Analysis of Serum G-17 and PG Levels in Ethnic Minority Patients with Gastric Cancer in Lijiang Area[J]. Journal of Kunming Medical University, 2023, 44(4): 133-138. doi: 10.12259/j.issn.2095-610X.S20230429

Citation:

Xiaoji LI, Xuefang YANG, Qian LIU, Chongxiang HE, Yong YANG, Guorong LI. Analysis of Serum G-17 and PG Levels in Ethnic Minority Patients with Gastric Cancer in Lijiang Area[J]. Journal of Kunming Medical University, 2023, 44(4): 133-138. doi: 10.12259/j.issn.2095-610X.S20230429

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Analysis of Serum G-17 and PG Levels in Ethnic Minority Patients with Gastric Cancer in Lijiang Area

doi: 10.12259/j.issn.2095-610X.S20230429

1.
Dept. of Pharmacy
2.
Dept. of Gastroenterology，Lijiang People’s Hospital affiliated to Kunming University of Science and Technology，Lijiang，Yunnan 674199，China

Received Date: 2022-11-28
Available Online: 2023-04-24
Publish Date: 2023-04-25

Abstract

Abstract

Objective This study aims to analyze the level of G-17 and PG in ethnic minority gastric cancer patients in Lijiang, and to investigate their value in gastric cancer screening. Methods Selected from July 2020 to August 2022, Lijiang people’s hospital of gastroscopy patients with gastric cancer and gastritis, the biopsy confirmed gastric cancer in 52 cases of minority patients as an observation group, further gastric cancer group for early gastric cancer group and advanced gastric cancer group, while the same gastroscopy diagnosis of chronic gastritis （atrophic gastritis, atrophic gastritis） in 105 cases of ethnic minority patients as a control group. Serum G-17, PGI, PGII, and PGR levels were collected for correlation analysis. Results The serum G-17 level in gastric cancer group and atrophic gastritis group was significantly higher than that in non-atrophic gastritis group （P < 0.05）. The serum PGⅡ level in gastric cancer group was significantly higher than that in atrophic gastritis group （P < 0.05）. The PGI level in early gastric cancer group was lower than that in advanced gastric cancer group, and the difference was statistically significant （P < 0.05）. The AUC values of serum G-17, PGI, PGII and PGR combined tests were higher than those of single test （P < 0.0001）. Conclusion Serum G-17 and PG can be used for the identification and screening of ethnic minority gastric cancer patients in Lijiang, as well as as non-invasive indicators of early and advanced gastric cancer.
- Gastric cancer,
- Gastrin-17,
- Pepsinogen,
- Correlation

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References(33)

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