The Study on Application Timing of Intra-aortic Balloon Pump in ST-egment- elevation Myocardial Infarction Patients Complicated with Ventricular Septal Rupture

Jie FANG; Xuefeng GUANG; Xiaofeng LIN; Hailong DAI; Tongxi ZUO; Qi LAI

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Jie FANG, Xuefeng GUANG, Xiaofeng LIN, Hailong DAI, Tongxi ZUO, Qi LAI. The Study on Application Timing of Intra-aortic Balloon Pump in ST-egment- elevation Myocardial Infarction Patients Complicated with Ventricular Septal Rupture[J]. Journal of Kunming Medical University.

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The Study on Application Timing of Intra-aortic Balloon Pump in ST-egment- elevation Myocardial Infarction Patients Complicated with Ventricular Septal Rupture

Dept. of Cardiology，Yan’an Hospital Affiliated to Kunming Medical University，Kunming Yunnan 650051，China

Received Date: 2024-07-24
Available Online: 2024-11-23

Abstract

Abstract

Objective To study the effect of intra-aortic balloon pump （IABP） in the therapy of ST-segment-elevation myocardial infarction （STEMI） patients complicated with ventricular septal rupture （VSR）. Methods A retrospective analysis was performed on 35 STEMI patients complicated with VSR. Those patients were admitted in Yan’ an Hospital Affiliated to Kunming Medical University from January 2019 to June 2023.Patients were divided into the combine-treated group （20 cases） and the drug-treated group （15 cases） according to the therapeutic strategies. The combine-treated group received IABP implantation and drug therapy, and the drug-treated group only received drug therapy. The clinical characteristics, hemodynamic and cardiac function improvement and mortality were evaluated. Hemodynamic and cardiac function improvement were compared between the two groups. Results There were no statistically significant differences in age, male proportion and size of VSR between the two groups （P > 0. 05） . In the combine-treated group, the average heart rate, the average arterial blood pressure, central venous pressure, the LVEF value of cardiac ultrasound, pleural effusion, B-Line of lung, the level of B-type natriuretic peptide （BNP）, the level of serum creatinine and the level of serum lactic acid were improved at 72 h after IABP use （all P < 0. 05）. All these indicators got worse in the drug-treated group. The mortality rate of the combine-treated group was markedly lower than that of the drug-treated group （P < 0.05）. The mortality rate of patients who received IABP implantation within 72 h after VSR was lower than that of patients who received IABP implantation beyond 72 h after VSR. Conclusion For patients with AMI complicated with VSR, implantation of IABP can significantly improve hemodynamics, cardiac function and reduce mortality.
- ST-egment-elevation myocardial Infarction,
- Ventricular septal rupture,
- Intra-aortic balloon pump,
- Application timing,
- Prognosis

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References(18)

References

[1]	Gaisendrees C,Hoffmann F,Kuffer L,et al. Functional uni-ventricular heart due to post-myocardial infarction ventricular septum rupture[J]. Echocardiography,2022,39(3):528-530.
[2]	Abuelatta R,Alrashidy T,Taha F,et al. Concomitant transcatheter closure of post-myocardial infarction ventricular septal defect and inferior wall aneurysm: case report[J]. European heart journal,2020,4(6):1-7.
[3]	Falcetta G,Pratali S,Martino A,et al. Repair of a giant left ventricular pseudoaneurysm with rupture of the interventricular septum[J]. General thoracic and cardiovascular surgery,2019,65(7):800-802.
[4]	Shafiei l,Jannati F,Jannati M. Optimal time repair of ventricular septal rupture post myocardial infarction[J]. J Saudi Heart Assoc,2020,32(2):288-294. doi: 10.37616/2212-5043.1120
[5]	Chris D,John M,Carlos A,et al. Noncongenital ventricular septal defects: A pictorial review[J]. J Thorac Imaging.,2018,33(4):22-29.
[6]	Ronco D,Matteucci M,Ravaux J M,et al. Mechanical circulatory support as a bridge to definitive treatment in post-infarction ventricular septal rupture[J]. JACC Cardiovasc Interv,2021,14(10):1053-1066. doi: 10.1016/j.jcin.2021.02.046
[7]	中华医学会心血管病学分会,中华心血管病杂志编辑委员会. 急性 ST 段抬高型心肌梗死诊断和治疗指南[J]. 中华心血管病杂志,2019,47(10):766-783.
[8]	方曙,汪璐芸,崔广林,等. 主动脉内球囊反搏改善急性心肌梗死后室间隔穿孔患者的临床疗效[J]. 内科急危重症杂志,2019,25(6):442-445.
[9]	Tan L,Fan X K,Jun L W,et al. Ventricular septal rupture with right ventricular wall dissection after inferior ventricular infarction: A case report and literature review[J]. J Clin Ultrasound,2019,47(4):247-252. doi: 10.1002/jcu.22684
[10]	Shi J,Levett J,Lv H,et al. Surgical repair of post myocardial infarction ventricular septal defect: a retrospective analysis of a single institution experience[J]. J Cardiothorac Surg,2023,18(1):313-313. doi: 10.1186/s13019-023-02418-8
[11]	Arsh H,Pahwani R,Rasul W,et al. Delayed ventricular septal rupture repair after myocardial infarction: An updated review[J]. Curr Probl Cardiol,2023,48(10):887.
[12]	Byung Wook L,Yong Sung C,Sung O,et al. Echocardiographic features of myocardial rupture after acute myocardial infarction on emergency echocardiography[J]. Clin Exp Emerg Med,2023,10(4):393-399. doi: 10.15441/ceem.23.037
[13]	李汉美,项理,许建屏,等. 急性心肌梗死后合并室间隔穿孔外科修复105例: 阜外医院16年随访结果[J]. 中国胸心血管外科临床杂志,2019,26(5):451-456.
[14]	李佳,罗晓亮,张峻,等. 急性心肌梗死并发游离壁破裂和室间隔穿孔患者的临床特征及预后比较[J]. 中国循环杂志,2019,34(7):653-657.
[15]	吕明芳,薛凌,杨雪苹,等. 急性心肌梗死合并不同部位心脏破裂的临床特征及预后[J]. 现代医院,2019,19(3):421-424.
[16]	陈同峰,孙子瑞,蒋亚鹏,等. 28例心肌梗死后室间隔穿孔介入封堵患者主动脉内球囊反搏应用分析[J]. 临床心血管病杂志,2020,36(5):423-428.
[17]	吴少威,刘成伟,易东,等. 主动脉内球囊反搏有效改善急性心肌梗死合并室间隔穿孔患者的循环[J]. 内科急危重症杂志,2023,9(2):129-132.
[18]	Furui M,Yoshida T,Kakii B,et al. Strategy of delayed surgery for ventricular septal perforation after acute myocardial infarction[J]. J Cardiol,2018,71(5):488-493. doi: 10.1016/j.jjcc.2017.10.016

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