Survey on Mental Disorders in HIV/AIDS Patients with End-stage Renal Disease on Hemodialysis

Guonian HE; Yongmei JIN; Bo TIAN; Shoukun CHEN; Nihong LU; Jun LIU

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Guonian HE, Yongmei JIN, Bo TIAN, Shoukun CHEN, Nihong LU, Jun LIU. Survey on Mental Disorders in HIV/AIDS Patients with End-stage Renal Disease on Hemodialysis[J]. Journal of Kunming Medical University.

Citation:

Guonian HE, Yongmei JIN, Bo TIAN, Shoukun CHEN, Nihong LU, Jun LIU. Survey on Mental Disorders in HIV/AIDS Patients with End-stage Renal Disease on Hemodialysis[J]. Journal of Kunming Medical University.

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Survey on Mental Disorders in HIV/AIDS Patients with End-stage Renal Disease on Hemodialysis

1.
School of Public Health，Dali University，Dali Yunnan 671000
2.
Department of Infectious Diseases I
3.
Hemodialysis Center
4.
Department of Respiratory and Critical Care Medicine，The Third People’s Hospital of Kunming，Kunming Yunnan 650041，China

Received Date: 2025-06-13
Available Online: 2025-09-16

Abstract

Abstract

Objective To investigate the incidence and clinical characteristics of anxiety, depression, and sleep disorders in people living with HIV （PLWH） and end-stage renal disease （ESRD） on maintenance hemodialysis （MHD）. Methods A cross-sectional study was conducted at Kunming Third People’ s Hospital from August to December 2024. We consecutively enrolled 51 HIV/AIDS patients with ESRD receiving MHD （HIV-HD group）, 50 non-HIV ESRD patients receiving MHD （HD group）, and randomly selected 102 non-dialysis PLWH at a 1∶2 ratio （HIV group）. The hospital anxiety and depression scale （HADS） was used to assess anxiety and depression, and the Pittsburgh sleep quality index （PSQI） was used to evaluate sleep quality. The incidence rates of these conditions were compared among the three groups. Results A total of 203 patients were included. The incidence rates of psychiatric disorders in HIV-HD, HD , and HIV groups were as follows: anxiety （25.5% vs. 22.0% vs. 7.8%）, depression （37.3% vs. 56.0% vs. 17.6%）, sleep disorders （86.3% vs. 90.0% vs. 40.2%）, comorbid anxiety and depression （15.7% vs. 20.0% vs. 3.9%）, comorbid anxiety and sleep disorders （23.5% vs. 22.0% vs. 3.9%）, comorbid depression and sleep disorders （33.3% vs. 54.0% vs. 9.8%）, and comorbid anxiety, depression, and sleep disorders （13.7% vs. 20.0% vs. 2.0%）. The incidence of these psychiatric disorders was significantly higher in both the HIV-HD and HD groups compared to the HIV group （P < 0.05）. Clinical characteristics revealed that the proportions of severe comorbidities （CCI≥5） and hypertension were significantly higher in the HIV-HD and HD groups than in the HIV group, while the prevalence of diabetes was higher in the HD group than in the HIV group （all P < 0.05）. Conclusion People living with HIV on hemodialysis have a higher incidence of anxiety and depression, and extremely poor sleep quality.
- HIV/AIDS,
- Maintenance hemodialysis,
- Anxiety,
- Depression,
- Sleep disorders

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References(39)

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