Turn off MathJax
Article Contents
Yanqiong RAO, Shujin LI, Jihua CUI, Yanhui SUN, Yu SONG, Yanfei YANG, Yu LING. Relationship between Infant Sleep and Cognitive Development[J]. Journal of Kunming Medical University.
Citation: Yanqiong RAO, Shujin LI, Jihua CUI, Yanhui SUN, Yu SONG, Yanfei YANG, Yu LING. Relationship between Infant Sleep and Cognitive Development[J]. Journal of Kunming Medical University.

Relationship between Infant Sleep and Cognitive Development

  • Received Date: 2025-12-08
    Available Online: 2026-01-13
  •   Objective  To explore the relationship between sleep patterns and cognitive development in children aged 6-35 months with sleep problems.   Methods  A total of 290 children (154 boys, 136 girls) aged 6~35 months with sleep problems, who presented to the Department of Child Health Care at Kunming Children’s Hospital between October 2023 and March 2025, were selected as the study subjects. Their sleep patterns and cognitive development levels were assessed using the Brief Infant Sleep Questionnaire (BISQ) and the Griffiths Development Scales-Chinese Language Edition (GDS-C), respectively. Linear regression analysis were employed to investigate the relationship between sleep and cognitive development.   Results   Both nighttime sleep duration and the frequency of nighttime awakenings were associated with development in the motor and personal-social domains (all P < 0.05). Linear regression analysis identified that a nighttime sleep duration of > 9 hours was beneficial for motor developmen (all P < 0.05). In contrast, the frequency of nighttime awakenings was negatively associated with both motor and personal-social development, showing adverse effects on these domains (all P < 0.05).   Conclusion  Sleep deprivation and nighttime awakenings are closely related to cognitive developmental levels in children aged 6-35 months. Therefore, sleep-related parenting guidance and intervention may serve as an effective approach to promote early childhood development.
  • loading
  • [1]
    Ventura S, Mathieson S R, O’Toole J M, et al. Electroencephalographic sleep macrostructure and sleep spindles in early infancy[J]. Sleep, 2022, 45(1): zsab262. doi: 10.1093/sleep/zsab262
    [2]
    Ryan M A J, Mathieson S R, Livingstone V, et al. Sleep state organisation of moderate to late preterm infants in the neonatal unit[J]. Pediatr Res, 2023, 93(3): 595-603. doi: 10.1038/s41390-022-02319-x
    [3]
    Scher A. Infant sleep at 10 months of age as a window to cognitive development[J]. Early Hum Dev, 2005, 81(3): 289-292. doi: 10.1016/j.earlhumdev.2004.07.005
    [4]
    Bernier A, Beauchamp M H, Bouvette-Turcot A A, et al. Sleep and cognition in preschool years: Specific links to executive functioning[J]. Child Dev, 2013, 84(5): 1542-1553. doi: 10.1111/cdev.12063
    [5]
    Mindell J A, Lee C. Sleep, mood, and development in infants[J]. Infant Behav Dev, 2015, 41: 102-107.
    [6]
    Spruyt K, Aitken R J, So K, et al. Relationship between sleep/wake patterns, temperament and overall development in term infants over the first year of life[J]. Early Hum Dev, 2008, 84(5): 289-296. doi: 10.1016/j.earlhumdev.2007.07.002
    [7]
    赵艳桃. 婴幼儿睡眠与认知发育相关性研究进展[J]. 中国儿童保健杂志, 2012, 20(9): 814-816.
    [8]
    孔莉芳, 王燕, 周书进, 等. 昼夜节律形成对婴幼儿认知发育影响的研究[J]. 中国妇幼健康研究, 2014, 25(2): 177-179+189. doi: 10.3969/j.issn.1673-5293.2014.02.002
    [9]
    王玉亭, 郝爱珍, 闫雅红, 等. 太原市435例0~2岁婴幼儿睡眠状况分析[J]. 中国妇幼保健, 2022, 37(12): 2232-2235. doi: 10.19829/j.zgfybj.issn.1001-4411.2022.12.030
    [10]
    钟平莉, 姜春花, 李云, 等. 上海市0 ~ 35个月婴幼儿睡眠状况及影响因素分析[J]. 教育生物学杂志, 2023, 11(2): 124-130. doi: 10.13723/j.yxysh.2025.08.002
    [11]
    刘卓娅, 郭玉琴, 宋娟娟, 等. 婴幼儿入睡方式及其对睡眠质量的影响[J]. 中国当代儿科杂志, 2022, 24(3): 297-302. doi: 10.7499/j.issn.1008-8830.2111004
    [12]
    国家卫生和计划生育委员会. 0岁~5岁儿童睡眠卫生指南: WS/T 579—2017[S]. 北京: 中国标准出版社, 2017.
    [13]
    Tso W W Y, Wong V C N, Xia X, et al. The Griffiths Development Scales-Chinese (GDS-C): A cross-cultural comparison of developmental trajectories between Chinese and British children[J]. Child Care Health Dev, 2018, 44(3): 378-383.
    [14]
    顾宇杭, 张海清, 贺文香, 等. Griffiths量表对孤独症谱系障碍儿童发育评估的意义[J]. 中国妇幼健康研究, 2020, 31(1): 6-10. doi: 10.3969/j.issn.1673-5293.2020.01.002
    [15]
    中国医师协会睡眠专业委员会儿童睡眠学组, 中华医学会儿科学分会儿童保健学组, 中国医师协会儿童健康专业委员会, 中华儿科杂志编辑委员会. 中国6岁以下儿童就寝问题和夜醒治疗指南(2023)[J]. 中华儿科杂志, 2023, 61(5): 388-397. doi: 10.3760/cma.j.cn112140-20230218-00110
    [16]
    饶艳琼, 许榛, 孙晶晶, 等. 月龄0~35的300名婴幼儿睡眠状况研究[J]. 昆明医科大学学报, 2023, 44(12): 79-86. doi: 10.12259/j.issn.2095-610X.S20231213
    [17]
    Shi S Q, Mahoney C E, Houdek P, et al. Circadian rhythms and sleep are dependent upon expression levels of key ubiquitin ligase Ube3a[J]. Front Behav Neurosci, 2022, 16: 837523. doi: 10.3389/fnbeh.2022.837523
    [18]
    Bhanudeep S, Madaan P, Sankhyan N, et al. Long-term epilepsy control, motor function, cognition, sleep and quality of life in children with West syndrome[J]. Epilepsy Res, 2021, 173: 106629.
    [19]
    Santos I M, Silva A, Bem-Haja P, et al. The impact of sleep on face recognition memory: A scoping review[J]. Brain Sci, 2022, 12(10): 1385. doi: 10.3390/brainsci12101385
    [20]
    Girardeau G, Lopes-Dos-Santos V. Brain neural patterns and the memory function of sleep[J]. Science, 2021, 374(6567): 560-564. doi: 10.1126/science.abi8370
    [21]
    Lewis L D. The interconnected causes and consequences of sleep in the brain[J]. Science, 2021, 374(6567): 564-568. doi: 10.1126/science.abi8375
    [22]
    Newbury C R, Crowley R, Rastle K, et al. Sleep deprivation and memory: Meta-analytic reviews of studies on sleep deprivation before and after learning[J]. Psychol Bull, 2021, 147(11): 1215-1240.
    [23]
    Mason G M, Lokhandwala S, Riggins T, et al. Sleep and human cognitive development[J]. Sleep Med Rev, 2021, 57: 101472. doi: 10.1016/j.smrv.2021.101472
    [24]
    Petit D, Touchette E, Pennestri M H, et al. Nocturnal sleep duration trajectories in early childhood and school performance at age 10 years[J]. J Sleep Res, 2023, 32(5): e13893.
    [25]
    吴倩芸, 热娜·买买提. 6—36月龄儿童智能发育筛查与就寝情况的相关探究[J]. 保健医学研究与实践, 2023, 20(S2): 20-23. doi: 10.11986/j.issn.1673-873X.2023.S2.05
    [26]
    罗蒙蒙, 陈红梅, 周慧, 等. 武汉市20—26月龄幼儿睡眠状况与认知发育水平的相关性研究[J]. 医学与社会, 2023, 36(5): 75-80. doi: 10.13723/j.yxysh.2023.05.013
    [27]
    Dzierzewski J M, Dautovich N, Ravyts S. Sleep and cognition in older adults[J]. Sleep Med Clin, 2018, 13(1): 93-106. doi: 10.1016/j.jsmc.2017.09.009
    [28]
    Gossé L K, Wiesemann F, Elwell C E, et al. Concordance between subjective and objective measures of infant sleep varies by age and maternal mood: Implications for studies of sleep and cognitive development[J]. Infant Behav Dev, 2022, 66: 101663. doi: 10.1016/j.infbeh.2021.101663
    [29]
    Bernier A, Carlson S M, Bordeleau S, et al. Relations between physiological and cognitive regulatory systems: Infant sleep regulation and subsequent executive functioning[J]. Child Dev, 2010, 81(6): 1739-1752. doi: 10.1111/j.1467-8624.2010.01507.x
    [30]
    周文娇, 王利刚, 李晔, 等. 睡眠时长对学龄前儿童认知功能的影响[J]. 北京大学学报(医学版), 2013, 45(6): 933-937. doi: 10.3969/j.issn.1671-167X.2013.06.022
    [31]
    Liang X, Zhang X, Wang Y, et al. Sleep problems and infant motor and cognitive development across the first two years of life: The Beijing Longitudinal Study[J]. Infant Behav Dev, 2022, 66: 101686. doi: 10.1016/j.infbeh.2021.101686
    [32]
    Ando A, Ohta H, Yoshimura Y, et al. Sleep maturation influences cognitive development of preterm toddlers[J]. Sci Rep, 2021, 11(1): 15921. [PubMed]
    [33]
    朱显显. 婴儿睡眠及其变化轨迹与一岁神经发育的关联研究[D]. 南京: 南京医科大学, 2024.
    [34]
    Pecora G, Focaroli V, Paoletti M, et al. Infant sleep and development: Concurrent and longitudinal relations during the first 8 months of life[J]. Infant Behav Dev, 2022, 67: 101719. doi: 10.1016/j.infbeh.2022.101719
    [35]
    Mäkelä T E, Peltola M J, Saarenpää-Heikkilä O, et al. Night awakening and its association with executive functioning across the first two years of life[J]. Child Dev, 2020, 91(4): e937-e951. doi: 10.1111/cdev.13326
    [36]
    Manacero S, Nunes M L. Longitudinal study of sleep behavior and motor development in low-birth-weight preterm children from infancy to preschool years[J]. J Pediatr, 2021, 97(1): 44-51. doi: 10.1016/j.jped.2019.10.010
    [37]
    Morales-Muñoz I, Nolvi S, Virta M, et al. The longitudinal associations between temperament and sleep during the first year of life[J]. Infant Behav Dev, 2020, 61: 101485. doi: 10.1016/j.infbeh.2020.101485
    [38]
    Fu X, Lovell A L, Braakhuis A J, et al. Type of milk feeding and introduction to complementary foods in relation to infant sleep: A systematic review[J]. Nutrients, 2021, 13(11): 4105. doi: 10.3390/nu13114105
  • Relative Articles

    [1] Yanqiong RAO, Zhen XU, Jingjing SUN, Ou ZHANG, Yu LING. Relationship between Sleep Problems and Temperament among Infants Aged 12~ 35 Months. Journal of Kunming Medical University,  doi: 10.12259/j.issn.2095-610X.S20250419
    [2] Yanzheng YANG, Yu’e ZHOU, Tuan LI, Li MA, sisi LI. Current Situation and Influencing Factors of Breast-feeding in Four Districts of Kunming. Journal of Kunming Medical University,  doi: 10.12259/j.issn.2095-610X.S20230624
    [3] Hang YANG, Hao ZOU, Zhao NA, Li CHEN, Hui FANG. Analysis of Risk Factors for Ovarian Necrosis with Ovarian Incarcerated Hernia. Journal of Kunming Medical University,  doi: 10.12259/j.issn.2095-610X.S20230221
    [4] Yanqiong RAO, Zhen XU, Jingjing SUN, Ou ZHANG, Sixiang LIU, Yu LING. Sleep Status in 300 Infants and Young Children Aged 0~ 35 Months. Journal of Kunming Medical University,  doi: 10.12259/j.issn.2095-610X.S20231213
    [5] Yong YUAN, Xinyi LI, Yan FU, Yan ZHU. Analysis of Vitamin D Level in Pregnant Women and Infants in Kunming and Study on the Relationship between Fasting Blood Glucose Level and Vitamin D Level during Pregnancy. Journal of Kunming Medical University,  doi: 10.12259/j.issn.2095-610X.S20220931
    [6] Linxia LI, Yanhong LI, Jie WU, Lili ZHANG, Xian ZHANG, Song WANG, Juntao ZHANG, Peng YAN. Studies on the Correlation between Serum Vitamin A, D and Lung Function in Infants with Asthmatic Pneumonia. Journal of Kunming Medical University,  doi: 10.12259/j.issn.2095-610X.S20220114
    [7] Yan GAO, Xiang-lei TONG, Hao-ran TANG, Li WU. Analysis of Serum Fat-soluble Vitamin Levels in Infants and Children in Anning City. Journal of Kunming Medical University,  doi: 10.12259/j.issn.2095-610X.S20210408
    [8] Li-zheng WEI, Jie-qing MIN, Jin-run TIAN, Yan-jie CAO, Peng PAN, Peng WANG, Yun-juan YANG, Yun-jiao LUO. The Characteristics of Echocardiography in Acute Incomplete Kawasaki Disease among Infants and Young Children in Yunnan Province. Journal of Kunming Medical University,  doi: 10.12259/j.issn.2095-610X.S20210923
    [9] Ma Rui , Li Yan . Research Progress of Exposure to Pyrethroid Pesticides Impact on Reproductive System of Human and Physical Development of Infants. Journal of Kunming Medical University,
    [10] Zhang Ling Peng , Huang Yue Su , Ma Ai Li , Xia Zhi Gang , Yu Hong Bin . Application of High-frequency Mono-polar Electronic Scalpel in Surgery with Ankyloglossi in Infants. Journal of Kunming Medical University,
    [11] Peng Jian Zhi . A Survey on Diet for Infants in Some Parts of Poor Areas of Yunnan. Journal of Kunming Medical University,
    [12] Sun Li Li . Research Progress of Rotavirus and Rotavirus Vaccine. Journal of Kunming Medical University,
    [13] Li Fu Ning . . Journal of Kunming Medical University,
    [14] Huang Jie . . Journal of Kunming Medical University,
    [15] Huang Jie . . Journal of Kunming Medical University,
    [16] Zhou Yi . . Journal of Kunming Medical University,
    [17] Luo Zhong Ming . . Journal of Kunming Medical University,
    [18] Li Yan . . Journal of Kunming Medical University,
    [19] Wen Yong . . Journal of Kunming Medical University,
    [20] . Effect of Early Swimming on Intelligence Development of Infants. Journal of Kunming Medical University,
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(6)

    Article Metrics

    Article views (113) PDF downloads(10) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return