Advances in the Study of Varenicline Combined with Nicotine Patches for the Treatment of Tobacco Dependence

Qiuqi WEI; Wenqian ZHAO; Ling LIU

doi:10.12259/j.issn.2095-610X.S20250421

Volume 46 Issue 4

Apr. 2025

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Qiuqi WEI, Wenqian ZHAO, Ling LIU. Advances in the Study of Varenicline Combined with Nicotine Patches for the Treatment of Tobacco Dependence[J]. Journal of Kunming Medical University, 2025, 46(4): 157-162. doi: 10.12259/j.issn.2095-610X.S20250421

Citation:

Qiuqi WEI, Wenqian ZHAO, Ling LIU. Advances in the Study of Varenicline Combined with Nicotine Patches for the Treatment of Tobacco Dependence[J]. Journal of Kunming Medical University, 2025, 46(4): 157-162. doi: 10.12259/j.issn.2095-610X.S20250421

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Advances in the Study of Varenicline Combined with Nicotine Patches for the Treatment of Tobacco Dependence

doi: 10.12259/j.issn.2095-610X.S20250421

Department of Respiratory Medicine，The First Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650032，China

Received Date: 2024-12-24
Available Online: 2025-04-07
Publish Date: 2025-04-25

Abstract

Abstract

China has the highest number of smokers in the world with more than 1 million tobacco-related deaths each year. Smoking cessation is a feasible intervention to reduce the prevalence of smoking-related diseases and premature deaths. The smoking cessation therapies approved for use in China are ineffective for some tobacco dependent patients. In order to further improve the rate of smoking cessation, a combination of medications can be chosen, including varenicline combined with nicotine replacement therapy. However, there are conflicting evaluation conclusions on the effectiveness and safety of combination therapy. This article aims to review the mechanism of action, efficacy, and safety of varenicline combined with nicotine replacement therapy in the treatment of tobacco dependence, aiming to provide a basis for this combination therapy.
- Varenicline,
- Nicotine patch,
- Tobacco dependence,
- Combination therapy,
- Efficacy

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References(23)

References

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