Correlation between T1 Mapping and Feature Tracking in Hypertrophic Cardiomyopathy

Yan ZHANG; Lei YANG; Na LI; Mingjie PANG

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Yan ZHANG, Lei YANG, Na LI, Mingjie PANG. Correlation between T1 Mapping and Feature Tracking in Hypertrophic Cardiomyopathy[J]. Journal of Kunming Medical University.

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Yan ZHANG, Lei YANG, Na LI, Mingjie PANG. Correlation between T1 Mapping and Feature Tracking in Hypertrophic Cardiomyopathy[J]. Journal of Kunming Medical University.

Yan ZHANG, Lei YANG, Na LI, Mingjie PANG. Correlation between T1 Mapping and Feature Tracking in Hypertrophic Cardiomyopathy[J]. Journal of Kunming Medical University.

Citation:

Yan ZHANG, Lei YANG, Na LI, Mingjie PANG. Correlation between T1 Mapping and Feature Tracking in Hypertrophic Cardiomyopathy[J]. Journal of Kunming Medical University.

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Correlation between T1 Mapping and Feature Tracking in Hypertrophic Cardiomyopathy

Yan ZHANG^{1, 2},
Lei YANG^{2, 3},
Na LI^{2, 3},
Mingjie PANG^{2, 3
,
,}

1.
Department of Magnetic Resonance Imaging，Yunnan Provincial First People’s Hospital，Kunming Yunnan 650032
2.
School of Medicine，Kunming University of Science and Technology，Kunming Yunnan 650032
3.
Department of Cardiology，Yunnan Provincial First People’s Hospital，Kunming Yunnan 650032，China

Received Date: 2025-04-10
Available Online: 2026-03-29

Abstract

Abstract

Objective To explore the correlation between T1mapping and feature tracking in patients with Hypertrophic Cardiomyopathy （HCM）. Methods Cardiac magnetic resonance （CMR） data were retrospectively collected from 86 HCM patients hospitalized at Yunnan Provincial First People's Hospital between January 2016 and July 2021. The differences in T1 values before and after contrast enhancement, extracellular volume （ECV）, longitudinal strain （LS）, circumferential strain （CS）, radial strain （RS）, and strain rate parameters were compared between the late gadolinium enhancement （LGE）-positive group （59 cases） and LGE-negative group （27 cases）. Results （1） Patients in the LGE-positive group were younger with a higher proportion of NYHA class III-IV, larger end-diastolic maximal wall thickness, and greater left ventricular mass index （P < 0.05）; （2） Pre-contrast T1 values were higher in the LGE（+） group compared to the LGE（-） group, and ECV values were elevated in the LGE-positive group （P < 0.05）; （3） In the LGE-positive group, global longitudinal strain （GLS） showed negative correlations with left ventricular mass index, left ventricular end-diastolic maximal wall thickness, LGE%, T1 value, and ECV （r = −0.418, P = 0.008; r = −0.711, P = 0.021; r = −0.621, P = 0.015; r = −0.372, P = 0.020; r = −0.583, P = 0.010, respectively）. Conclusion In HCM patients with myocardial enhancement, GLS is reduced in LGE-positive cases, which shows significant negative correlations with left ventricular end-diastolic volume, left ventricular mass index, end-diastolic maximal wall thickness, LGE%, and pre-contrast T1 value and ECV.
- Hypertrophic cardiomyopathy,
- T1mapping,
- Extracellular volume,
- Delayed enhancement,
- Global longitudinal strain

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References(33)

References

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