Research Progress of Ultrasound and Related Technologies in the Diagnosis and Treatment of Pancreatic Cancer

Ziyu WANG; Liang LIU; Wenyuan SHI; Hao ZOU

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Ziyu WANG, Liang LIU, Wenyuan SHI, Hao ZOU. Research Progress of Ultrasound and Related Technologies in the Diagnosis and Treatment of Pancreatic Cancer[J]. Journal of Kunming Medical University.

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Ziyu WANG, Liang LIU, Wenyuan SHI, Hao ZOU. Research Progress of Ultrasound and Related Technologies in the Diagnosis and Treatment of Pancreatic Cancer[J]. Journal of Kunming Medical University.

Ziyu WANG, Liang LIU, Wenyuan SHI, Hao ZOU. Research Progress of Ultrasound and Related Technologies in the Diagnosis and Treatment of Pancreatic Cancer[J]. Journal of Kunming Medical University.

Citation:

Ziyu WANG, Liang LIU, Wenyuan SHI, Hao ZOU. Research Progress of Ultrasound and Related Technologies in the Diagnosis and Treatment of Pancreatic Cancer[J]. Journal of Kunming Medical University.

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Research Progress of Ultrasound and Related Technologies in the Diagnosis and Treatment of Pancreatic Cancer

Ziyu WANG^{1, 2},
Liang LIU³,
Wenyuan SHI²,
Hao ZOU^{1, 4
,
,}

1.
The Second Clinical Medical College of Kunming Medical University，Kunming Yunnan 650101
2.
Department of Hepatobiliary and Pancreatic Surgery, The First People’s Hospital of Yunnan Province, Kunming Yunnan 650032
3.
Department of Pancreatic Surgery，Zhongshan Hospital，Fudan University，Shanghai 200032
4.
Department of Hepatobiliary and Pancreatic Surgery，The Second Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650101，China

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Corresponding author: 邹浩、男、博士、教授、硕士研究生导师，昆明医科大学第二附属医院肝胆胰外科二病区科室主任，主要从事肝胆胰外科疾病微创诊治以及胆道恶性肿瘤的基础与临床研究。美国MD安德森癌症中心、日本国立国家医疗中心、东京大学附属病院、杏林大学附属病院、泰国朱拉隆功国王纪念医院访问学者。云南省科技项目、江西省科技项目评审专家；国家临床重点专科肝胆外科核心成员，欧美同学会医师分会青年委员（全国），中国抗癌协会环境肿瘤专委会委员，中国医师协会外科临床研究工作组委员、肝癌专委会医工交叉学组委员，云南省医学会外科学分会常委、胆道外科学组副组长及肠内肠外营养分会常委、小儿外科分会委员、肿瘤学分会青委，云南省医师协会微无创专业委员会常委，云南省抗癌协会常务理事、肝癌专委会副主任委员、临床肿瘤协作专委会委员、腹腔镜与机器人专委会常委，云南省预防医学会肿瘤预防与控制专委会常委、胰腺癌防治专委会副主委，云南省普通外科医疗质量控制中心专家委员会委员，云南省肝胆外科创新团队成员，云南省高校肝胆外科科技创新团队核心成员；《中国普通外科杂志》《中华肿瘤防治杂志》中青年编委兼审稿人，BMC Cancer，International Journal of Oncology等SCI收录医学杂志审稿人。主持省重点项目2项、面上项目3项；以第一作者及通讯作者身份发表学术论文51篇、其中SCI收录14篇，主编专著1部、副主编专著2部、参编专著1部、参译专著3部；参与撰写全国专家共识3篇；授权发明专利3项、实用新型专利1项、软件著作权2项。
Received Date: 2026-07-13
Available Online: 2026-10-28

Abstract

Abstract

Pancreatic cancer, particularly pancreatic ductal adenocarcinoma （PDAC）, has an insidious onset and rapid progression, and early diagnosis and precision treatment remain challenging. Contrast-enhanced CT and MRI/MRCP remain the basis for staging and resectability assessment, whereas ultrasound-related technologies is primarily reflected in high-resolution local evaluation, tissue acquisition, and interventional support. Current evidence indicates that endoscopic ultrasound （EUS） and EUS-guided fine-needle biopsy （EUS-FNB） have become mature key techniques for detecting small lesions, local staging, and obtaining tissue for histopathologic and molecular analyses. EUS-guided biliary drainage and celiac plexus neurolysis have established palliative roles in selected patients with biliary obstruction or cancer-related pain. By contrast, Contrast-enhanced EUS, elastography, and artificial intelligence are primarily adjunctive tools for lesion characterization, target selection, and quality improvement, while EUS-guided radiofrequency ablation, high-intensity focused ultrasound, and local delivery remain in the exploratory stage. The main evidence gaps include patient selection, technical parameters, optimal integration with systemic therapy, and confirmation of survival benefit through multicenter randomized studies. This review summarizes the clinical positioning, key quantitative evidence, and future research priorities of ultrasound and related technologies in the diagnosis and treatment of pancreatic cancer according to the above evidence levels.
- Pancreatic cancer,
- Endoscopic ultrasound,
- Tissue acquisition,
- Interventional ultrasound,
- Ultrasound-guided therapy

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References(47)

References

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