A Systematic Evaluation of Incidence and Influencing Factors of Falls in Adult Cancer Patients

Shiyao YANG; Yanxia YANG; Haiyin YANG; Yong DONG; Jinhu MIAO; Yuexi ZHU; Qiongyao GUAN

Article Contents

Article Navigation > Journal of Kunming Medical University > 2024 >

Shiyao YANG, Yanxia YANG, Haiyin YANG, Yong DONG, Jinhu MIAO, Yuexi ZHU, Qiongyao GUAN. A Systematic Evaluation of Incidence and Influencing Factors of Falls in Adult Cancer Patients[J]. Journal of Kunming Medical University.

Citation:

PDF( 999 KB)

A Systematic Evaluation of Incidence and Influencing Factors of Falls in Adult Cancer Patients

1.
Dept. of Nursing，The 3rd Affiliated Hospital of Kunming Medical University，Kunming Yunnan 650118
2.
Dept. of Pulmonary and Critical Care Medicine People’s Hospital of Dali Bai Autonomous Prefecture，Dali Yunnan 671000，China

Received Date: 2024-07-05
Available Online: 2024-11-23

Abstract

Abstract

Objective To systematically evaluate the incidence and influencing factors of falls in adult cancer patients, and provide evidence support for early identification and prevention of falls. Methods Eight Chinese and English databases, including PubMed, Embase, CNKI, and Wanfang Database, were searched by computer. The databases were established until January 2024 and included in cross-sectional, cohort, and case-control studies based on the incidence and/or influencing factors of falls in adult cancer patients. Two researchers independently screened and reviewed literature, evaluated literature quality, and extracted data before conducting meta-analysis using RevMan 5.4 software. Results A total of 19 articles were incorporated into the research, with a total sample population size of 70508 cases. The results showed that the incidence of comorbid falls in adult tumor patients was 23.0% （95%CI 0.23, 0.24）. Age, female, low education level, fall history, fall fear, middle and late stage of tumor, tumor type （breast cancer, reproductive system tumor, prostate cancer）, comorbidity, chemotherapy, radiotherapy, multiple drugs （n ≥ 5）, drugs （antidepressants, antipsychotics, sedatives and hypnotics）, related symptoms （fever, peripheral neuropathy, fatigue, depression）, malnutrition, low weight, cognitive dysfunction, balance disorders, gait abnormalities, and low ability of daily living were the influencing factors for falls of adult tumor patients. Conclusion Cancer professionals should identify the influencing factors of falls early and take targeted measures to reduce the occurrence of falls.
- Tumor,
- Fall,
- Incidence,
- Influencing factors,
- Systematic evaluation

FullText(HTML)

References(36)

References

[1]	Sung H,Ferlay J,Siegel R L,et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries[J]. CA Cancer J Clin.,2021,71(3):209-249. doi: 10.3322/caac.21660
[2]	Melissa S,Kathy M,Thomas S,et al. Addressing falls among older oncology patients through complexity science.[J]. Nursing Administration Quarterly,2019,43(3):280-288. doi: 10.1097/NAQ.0000000000000360
[3]	Capone L J,Albert N M,Bena J F,Tang A S. Predictors of a fall event in hospitalized patients with cancer[J]. Oncol Nurs Forum,2012,39(5):E407-E415.
[4]	Hiroko K ,Kaori Y ,Yasuhiro K ,et al. Falls and functional impairments in breast cancer patients with chemotherapy-induced peripheral neuropathy[J]. Asia-Pacific Journal of Oncology Nursing,2019,6(3):253-260.
[5]	Zhao J,Wang G,Chen L,Yu S,Li W. Risk factors for falls in hospitalized patients with cancer:A systematic review and meta-analysis[J]. Asia Pac J Oncol Nurs,2022,9(8):100107. doi: 10.1016/j.apjon.2022.100107
[6]	Hiroko K ,Kaori Y,Yasuo H ,et al. Falls and physical inactivity in patients with gastrointestinal cancer and hand-foot syndrome[J]. Asia-Pacific Journal of Oncology Nursing,2018,5(3):307-313.
[7]	Argyriou A A,Bruna J,Anastopoulou G G ,Velasco R,Litsardopoulos P,Kalofonos HP. Assessing risk factors of falls in cancer patients with chemotherapy-induced peripheral neurotoxicity[J]. Support Care Cancer,2020,28(4):1991-1995. doi: 10.1007/s00520-019-05023-5
[8]	Ting B,Coby B,Christina S,et al. Long-term chemotherapy-induced peripheral neuropathy among breast cancer survivors: prevalence,risk factors,and fall risk.[J]. Breast Cancer Research and Treatment,2016,159(2):327-33. doi: 10.1007/s10549-016-3939-0
[9]	Tuo-Yu C ,C M J. Predictors of falls among community-dwelling older adults with cancer: results from the health and retirement study[J]. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer,2014,22(2):479-85.
[10]	Huang H M ,Blackwood J ,Godoshian M ,et al. Predictors of falls in older survivors of breast and prostate cancer: A retrospective cohort study of surveillance,epidemiology and end results—Medicare health outcomes survey linkage[J]. Journal of Geriatric Oncology,2018,10(1):89-97.
[11]	Huang MH,Shilling T,Miller KA,Smith K,LaVictoire K. History of falls,gait,balance,and fall risks in older cancer survivors living in the community[J]. Clin Interv Aging,2015,10:1497-1503. doi: 10.2147/CIA.S89067
[12]	Cindy K ,Lore D ,Johan F ,et al. Incidence of falls and fall-related injuries and their predictive factors in frail older persons with cancer: A multicenter study[J]. BMC Geriatrics,2022,22(1):877-877.
[13]	Kong Q ,Wang Y ,Song C ,et al. Prospective analysis of the risk factors for falls in lymphoma patients[J]. European Journal of Oncology Nursing,2014,18(5):540-544.
[14]	Nayan L ,Fang C ,N D C ,et al. Frequency,etiologies,risk factors,and sequelae of falls among patients with brain metastases: A population- and institutional-level analysis[J]. Neuro-oncology Practice,2022,9(2):114-122.
[15]	Pandya C ,Magnuson A ,Dale W ,et al. Association of falls with health-related quality of life (HRQOL) in older cancer survivors: A population based study[J]. Journal of Geriatric Oncology,2016,7(3):201-210.
[16]	Najmeh S ,Ali K D ,Mahnaz I ,et al. Falls in older ambulatory care patients with cancer in Iran: Implications for clinical practice[J]. Journal of Evaluation in Clinical Practice,2021,28(4):624-630.
[17]	Nida R ,Akkradate S ,Sujitra B. Incidence and risk factors associated with falls among women with breast cancer during taxane-based chemotherapy[J]. Supportive care in cancer : Official journal of the Multinational Association of Supportive Care in Cancer,2022,30(9):7499-7508.
[18]	Puts M T,Monette J,Girre V,et al. The fall rate of older community-dwelling cancer patients[J]. Support Care Cancer.,2013,21(3):775-783.
[19]	Turner,Justin P et al. “Factors associated with use of falls risk-increasing drugs among patients of a geriatric oncology outpatient clinic in Australia: A cross-sectional study”[J]. Journal of Evaluation in Clinical Practice,2017,23(2):361-368.
[20]	Nathalie W V ,Cindy K ,Pieter H ,et al. Fall predictors in older cancer patients: A multicenter prospective study[J]. BMC Geriatrics,2014,14(2):135.
[21]	Wildes T M,Maggiore R J,Tew W P,et al. Factors associated with falls in older adults with cancer: A validated model from the Cancer and Aging Research Group[J]. Support Care Cancer,2018,26(10):3563-3570. doi: 10.1007/s00520-018-4212-3
[22]	刘伟,刘晓明. 老年乳腺癌全乳切除术后患者跌倒发生情况及其影响因素[J]. 中国老年学杂志,2021,41(18):4101-4104. doi: 10.3969/j.issn.1005-9202.2021.18.060
[23]	James S L,Lucchesi L R,Bisignano C et al. The global burden of falls: global,regional and national estimates of morbidity and mortality from the global burden of disease study 2017[J]. Inj Prev,2020,26:3-11.
[24]	康宁,于海军,陆晓敏等. 中国老年人跌倒发生率的Meta分析[J]. 中国循证医学杂志,2022,22(10):1142-1148.
[25]	杨欣,姚梅琪,张玉萍等. 住院老年患者跌倒风险与风险感知的差异性研究[J]. 中华护理杂志,2023,58(19):2326-2332.
[26]	荆凤,王园园,邢唯杰等. 乳腺癌患者芳香化酶抑制剂诱导的骨关节症状预防和管理的证据总结[J]. 中华护理杂志,2023,58(7):808-815.
[27]	Sattar S,Kenis C,Haase K,et al. Falls in older patients with cancer: Nursing and allied health group of international society of geriatric oncology review paper[J]. J Geriatr Oncol,2020,11(1):1-7. doi: 10.1016/j.jgo.2019.03.020
[28]	张雨欣,张开利. 老年人恐惧跌倒相关性活动限制的研究进展[J]. 中华护理杂志,2023,58(1):112-116. doi: 10.3761/j.issn.0254-1769.2023.01.016
[29]	任晓华,关琼瑶,马祥萍,等. 云南省肿瘤科护士癌痛知识知晓及癌痛护理开展现状调查[J]. 昆明医科大学学报,2021,42(9):167-172.
[30]	李思思,张艳,李宏洁,等. 老年癌症患者共病的研究进展[J]. 中国全科医学,2020,23(7):880-883+888.
[31]	田露,陈英,龙艳慧,等. 肿瘤患者化疗后居家跌倒预防自我管理体验的质性研究[J]. 中华护理杂志,2020,55(11):1648-1652. doi: 10.3761/j.issn.0254-1769.2020.11.008
[32]	中国抗癌协会肿瘤支持治疗专业委员会,中国抗癌协会肿瘤临床化疗专业委员会. 化疗诱导的周围神经病变诊治中国专家共识(2022版). 中华肿瘤杂志,2022,44(9): 928-934.
[33]	王静,罗雨田,叶琼告,等. 宫颈癌化疗病人癌因性疲乏程度及影响因素分析[J]. 护理研究,2021,35(4):630-633.
[34]	Strini V,Schiavolin R,Prendin A. Fall Risk Assessment Scales: A Systematic Literature Review[J]. Nurs Rep,2021,11(2):430-443.
[35]	肖先皓,宋禾,周建平. 肿瘤相关性肌肉减少症的发病危险因素分析—一项基于NHANES数据库的研究[J]. 中国实用外科杂志,2024,44(2):194-198.
[36]	周华萍,甘彩芳,程菁,等. 营养状态指标对老年食管癌患者化疗耐受性的影响[J]. 中国老年学杂志,2024,44(4):802-805. doi: 10.3969/j.issn.1005-9202.2024.04.011

Relative Articles(20)

Relative Articles

[1]	Yong DONG, Shuaizhong CAI, Haiyin YANG, Jiao YANG, Shiyao YANG, Yuexi ZHU, Jinhu MIAO, Qiongyao GUAN. The Current State and Influencing Factors of Medical Narrative Ability Among 931 Oncology Nurses. Journal of Kunming Medical University,
[2]	Shumei QIU, Jingrui YANG, Xuecai QIU. The Risk and Influencing Factors of Vascular Dementia in Middle-aged and Elderly People in Kunming. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20240914
[3]	Bo TIAN, Yongmei JIN, Haiwen LI, Chongxi LI, Wei ZHANG, Wei GUAN, Haiyun CHEN, Qi XUE, Huirong YANG, Jun LIU. Analysis of the Current Status and Influencing Factors of Metabolic Syndrome in Patients Undergoing Antiretroviral Therapy for AIDS. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20241121
[4]	Qingmei YU, Tao SHI, Hongxue GUAN, Yujun MAO, Zhaoyi LI, Jiao YANG. Prevalence and Influence Factors of Renal Function Impairment in Patients Following Radical Cystectomy：A Systematic Review and Meta-analysis. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20240913
[5]	Xi LIU, Xin LIU, Jingjing CAI, Yaxi DU, Hongsheng LI, Yongchun ZHOU. Application of Nanopore Sequencing in Tumor with Infection. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20230710
[6]	Chenglu HE, Ya LI, Min ZHU, Min ZHONG, Yong DUAN. Research Progress of ACSM Protein Family in Tumor. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20230307
[7]	Puxian PENG, Liping WANG, Hong LI, Yuan ZHANG, Songyuan TANG, Xingmei DENG. The Incidence of Premature Delivery and Its Influencing Factors: A Maternal and Infant Health Cohort Study. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20230505
[8]	Wen YANG, Fang YAN, Anqi KANG, Jinrong WANG, Ziyan WU, Chuanzhi XU, Yongbing XIA. The Current Situation and Related Factors of Alcohol Dependence among Dulong Ethnic Residents in Yunnan Province. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20230513
[9]	Qing-huan YANG, Hai-liang RAN, Jin-chun YU, Yan-qin RUAN, Ying CHEN. The Analysis of Incidence Trend of Tumor in Shilin County, Kunming City from 2016 to 2018. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20210510
[10]	Sheng-hao LI, Jie DING, Qing-qing WANG, Si-qi LIU, Li-juan HUA, Jin-yu DUAN, Bao-li BO, An-rui DU, Guo-ji CHANG, Jun-yi LI. Influencing Factors of Moderate to Severe Liver Injury in Patients with Chronic Hepatitis B and NAFLD. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20210712
[11]	Xiu-qing WANG, Xin-tian LONG, Yong MAO, Jie CHEN, Jia ZHOU, Tian-shu CHU, Song-mei WANG, Cheng-huan SUN, Chun-mi LAI, Qian ZHANG. Prevalence and Determinants of Hypertension in Senior Nu Ethnic Group. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20210922
[12]	Xin-tian LONG, Jie CHEN, Yong MAO, Xiu-qing WANG, Shuang-yan LU, Hui-jie PU, Jia ZHOU, Cheng-huan SUN, Song-mei WANG, Ai-fang YE. Detection Rate and Determinants of Hypertension among Seniors in Anning City. Journal of Kunming Medical University, doi: 10.12259/j.issn.2095-610X.S20211210
[13]	Liu Hai Tao , Zhao Wai Rong , Zhang Wei Qiang , Tian Jian Hui . . Journal of Kunming Medical University,
[14]	Zhang Tian , Tang Wei , Ji Fang , He Cheng Yu , Cui Nian Qi , Gan Xiu Ni . Application of ISBAR Standard Communication Tool in Hemodialysis Patients at High Risk of Falling and the Impact on the Patients' Satisfaction of the Nurses. Journal of Kunming Medical University,
[15]	Tao Yan Ping . . Journal of Kunming Medical University,
[16]	Yang Jian Yi . . Journal of Kunming Medical University,
[17]	Zeng Hai Ping . . Journal of Kunming Medical University,
[18]	Zhou Jie . . Journal of Kunming Medical University,
[19]	. The Incidence of Acute Kindey Injury in Acute Decompensated Heart Failure and the Influencing Factors Analysis. Journal of Kunming Medical University,
[20]	Zhang Cheng Hua . The Study of CT Perfusion Imaging in the Diagnosis of Acute Cerebral Ischemia. Journal of Kunming Medical University,