Research Progress in the Cohort Study of Native Plateau Populations at High-Altitude in Southwest China

Zhuohang CHE; Ying QIAN; Qiong MENG; Xuehui ZHANG; Chuanwen FU; Xing ZHAO; Jianzhong YIN

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Zhuohang CHE, Ying QIAN, Qiong MENG, Xuehui ZHANG, Chuanwen FU, Xing ZHAO, Jianzhong YIN. Research Progress in the Cohort Study of Native Plateau Populations at High-Altitude in Southwest China[J]. Journal of Kunming Medical University.

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Research Progress in the Cohort Study of Native Plateau Populations at High-Altitude in Southwest China

1.
School of Public Health，Kunming Medical University，Kunming Yunnan 650500
2.
Baoshan Center for Disease Control and Prevention，Baoshan Yunnan 678099
3.
West China School of Public Health and West China Fourth Hospital，Sichuan University，Chengdu Sichuan 610041，China

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Corresponding author: 殷建忠，二级教授，博士生导师，国务院政府特殊津贴专家，云岭教学名师，国家级一流本科课程负责人，教育部首届高校健康教育教指委委员，健康云南发展智库首席专家，云南省高校营养与食品安全重点实验室主任、精准营养与公共健康博士生导师团队带头人，省级专家工作站项目负责人。研究领域：营养流行病学。主持国家重点研发计划课题1项、国家自然科学基金 4 项、云南省科技厅基础研究专项计划重点项目1项。获云南省哲学社会科学优秀成果一等奖1项、科技进步三等奖 4 项、卫生科技成果二等奖1项及三等奖3项，省高等教育教学成果奖二等奖。代表性成果发表于The Lancet、The Lancet Reg Health West Pac、JHEP Reports、eLife等期刊，入选ESI高水平论文2篇，在The BMJ发表Rapid Response 18篇。2篇咨询报告被云南哲学社会科学成果要报、《云南日报内参》采用。
Received Date: 2025-11-01
Available Online: 2026-01-03

Abstract

Abstract

In recent years, the burden of chronic diseases in China has been continuously escalating with significant regional disparities. The local indigenous populations residing in the high-altitude areas of Southwest China have developed unique physiological and genetic traits due to specific geographical and multi-ethnic factors, confronting health challenges such as cardiovascular diseases and metabolic disorders. To conduct a comprehensive analysis the disease distribution patterns and potential exposure factors among this population and to address the data gaps regarding the prevalence of non-communicable diseases （NCDs）, risk factors, and related conditions in resource-limited areas with multi-ethnic groups. This study relies on the china multi-ethnic cohort （CMEC） study has established high-altitude natural population cohorts in Lijiang （Yunnan）, Aba （Sichuan）, and Lhasa （Tibet） to systematically collect baseline data. While health outcomes were monitored through standardized follow-ups to reveal the prevalence rates and their primary risk factors of chronic diseases in high-altitude regions. To explore the impacts of dietary patterns and lifestyle on the metabolic health of plateau populations, discover novel intervention technologies and strategies for chronic diseases, and provide theoretical support for the prevention and control of chronic diseases in Southwest China and even the whole country.
- Southwest China,
- High-altitude,
- Multi-ethnic,
- Chronic diseases,
- Risk factors

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References(84)

References

[1]	Manolio T A, Goodhand P, Ginsburg G. The International Hundred Thousand Plus Cohort Consortium: Integrating large-scale cohorts to address global scientific challenges[J]. Lancet Digit Health, 2020, 2(11): e567-e568. doi: 10.1016/S2589-7500(20)30242-9
[2]	Zhou Y, Lai H, Xu C. Global trends and age-period-cohort effects of chronic respiratory disease mortality attributed to industrial gaseous pollutants from 1990 to 2021[J]. Sci Rep, 2025, 15: 11924. doi: 10.1038/s41598-025-90406-4
[3]	Edwards N, Plotnikoff R C. Mobilizing an underused resource: Cohort studies for population health intervention research[J]. Int J Epidemiol, 2018, 47(6): 1730-1733.
[4]	Doll R, Hill A B. Smoking and carcinoma of the lung[J]. Bmj, 1950, 2(4682): 739-748. doi: 10.1136/bmj.2.4682.739
[5]	Lin Y, Chen L, Huang J, et al. Breadth versus depth: Balancing variables, sample size, and quality in Chinese cohort studies[J]. Bmj, 2025, 391: e082566. doi: 10.1136/bmj-2024-082566
[6]	China Cohort Sharing Platform(CCSP) [Z]. https://cohortconsortium.com/queues
[7]	熊燕, 孟晶, 毛开云, 等. 自然人群前瞻性队列建设现状与趋势[J]. 中国临床医学, 2025, 32(05): 841-55.
[8]	Zhao X, Hong F, Yin J, et al. Cohort profile: The China multi-ethnic cohort (CMEC) study[J]. Int J Epidemiol, 2021, 50(3): 721-721l. doi: 10.1093/ije/dyaa185
[9]	赵星, 洪峰, 殷建忠, 等. 西南区域自然人群队列简介与研究进展[J]. 中华流行病学杂志, 2023, 44(1): 40. doi: 10.3760/cma.j.cn112338-20221009-00864
[10]	Bigham A W, Lee F S. Human high-altitude adaptation: Forward genetics meets the HIF pathway[J]. Genes Dev, 2014, 28(20): 2189-2204. doi: 10.1101/gad.250167.114
[11]	Huang T, Zhang X, Li Q, et al. The association between obesity susceptibility and polymorphisms of MC4R, SH2B1, and NEGR1 in tibetans[J]. Genet Test Mol Biomark, 2024, 28(7): 267-274. doi: 10.1089/gtmb.2023.0546
[12]	曾永利. 云南高原偏寒地区汉族人群辣食摄入与肥胖关联研究及其机制探索 [D]; 昆明医科大学, 2022.
[13]	Zhou J, He R, Shen Z, et al. Altitude and metabolic syndrome in China: Beneficial effects of healthy diet and physical activity[J]. J Glob Health, 2023, 13: 04061. doi: 10.7189/jogh.13.04061
[14]	高留飞. 云南哈尼族和纳西族居民血清Visfatin、A-FABP水平及与慢性病关系的对比研究 [D]; 昆明医科大学, 2019.
[15]	Tang D, Xiao X, Chen L, et al. Association of dietary patterns with obesity and metabolically healthy obesity phenotype in Chinese population: A cross-sectional analysis of China Multi-Ethnic Cohort Study[J]. Br J Nutr, 2022, 128(11): 2230-2240. doi: 10.1017/S0007114521005158
[16]	Qian Y, Che Z, Fu C, et al. Study on the association between dietary quality and overweight/obesity of Han nationality with cold in Yunnan Plateau by DBI-16–a study based on a multi-ethnic cohort in China[J]. Diabetes Metab Syndr Obes, 2023, 16: 2311-2327. doi: 10.2147/DMSO.S420260
[17]	Deng Q, Yin J, Peng J, et al. Altitude differences in changes in physical activity and weight gain[J]. Asia Pac J Public Health, 2025, 37(4): 371-378. doi: 10.1177/10105395251325620
[18]	Zhao Z, Huang J, Zhong D, et al. Associations of three thermogenic adipokines with metabolic syndrome in obese and non-obese populations from the China plateau: The China Multi-Ethnic Cohort[J]. BMJ Open, 2023, 13(7): e066789. doi: 10.1136/bmjopen-2022-066789
[19]	Zhang T, Huang J, Li Y, et al. Plasma fatty acids, not dietary fatty acids, associated with obesity in four ethnic minority groups unique to southwest China: A cross-sectional study[J]. Diabetes Metab Syndr Obes Targets Ther, 2022, 15: 3753-3765. doi: 10.2147/DMSO.S386812
[20]	陈果. 云南高原偏寒冷地区汉族肥胖人群血清Visfatin、A-FABP水平及其影响因素研究 [D]; 昆明医科大学, 2020.
[21]	郭艳东. 云南高原偏寒地区汉族PPARγ2基因Pro12Ala、C161-T多态性与肥胖的关联研究 [D]; 昆明医科大学, 2020.
[22]	钱映. 云南高原偏寒地区汉族自然人群肥胖与肠道菌群的相关性研究 [D]; 昆明医科大学, 2022.
[23]	Qian Y, Zeng Y, Mi F, et al. Gut microbiota bridging spicy food intake and obesity: Evidence from the China Multi-Ethnic Cohort (CMEC) study[J]. BMC Public Health, 2025, 25(1): 3267. doi: 10.1186/s12889-025-23936-1
[24]	黄娟. 高浓度瘦素抑制脂肪组织线粒体自噬诱导肥胖的机制研究 [D]; 昆明医科大学, 2023.
[25]	洪汝丹. 基于云南偏寒地区肥胖人群研究抑制ACE轴/激活ACE2轴抗肥胖作用及机制 [D]; 昆明医科大学, 2023.
[26]	Zhang M, Zhu X, Wu J, et al. Prevalence of hyperuricemia among Chinese adults: Findings from two nationally representative cross-sectional surveys in 2015–16 and 2018–19[J]. Front Immunol, 2022, 12: 791983. doi: 10.3389/fimmu.2021.791983
[27]	Hong R, Huang J, Xu C, et al. Association of sedentary behavior and physical activity with hyperuricemia and sex differences: Results from the China multi-ethnic cohort study[J]. J Rheumatol, 2022, 49(5): 513-522. doi: 10.3899/jrheum.211180
[28]	Wang Y, Zeng Y, Zhang X, et al. Daytime napping duration is positively associated with risk of hyperuricemia in a Chinese population[J]. J Clin Endocrinol Metab, 2021, 106(5): e2096-e2105. doi: 10.1210/clinem/dgab043
[29]	Wu X, Tang W, Tang D, et al. Two a posteriori dietary patterns are associated with risks of hyperuricemia among adults in less-developed multiethnic regions in Southwest China[J]. Nutr Res, 2023, 110: 96-107. doi: 10.1016/j.nutres.2022.12.012
[30]	Wang Y, Xu F, Zhang X, et al. Cross-sectional association between gamma-glutamyl transferase and hyperuricaemia: The China Multi-Ethinic Cohort (CMEC) study[J]. BMJ Open, 2022, 12(5): e058793. doi: 10.1136/bmjopen-2021-058793
[31]	Chen K, Yin J, Dai Y, et al. Associations of long-term exposure to PM_2.5 constituents with serum uric acid and hyperuricemia in Chinese adults[J]. Environ Sci Eur, 2023, 35(1): 101. doi: 10.1186/s12302-023-00809-1
[32]	Deng H, Zhang X, Cheng N, et al. Asymptomatic hyperuricemia associated with increased risk of nephrolithiasis: A cross-sectional study[J]. BMC Public Health, 2023, 23(1): 1525. doi: 10.1186/s12889-023-16469-y
[33]	Liang N, Yuan X, Zhang L, et al. Fatty acid oxidation-induced HIF-1α activation facilitates hepatic urate synthesis through upregulating NT5C2 and XDH[J]. Life Metab, 2024, 3(5): loae018. doi: 10.1093/lifemeta/loae018
[34]	Essawy S S, Abdel-Sater K A, Elbaz A A. Experimental research Comparing the effects of inorganic nitrate and allopurinol in renovascular complications of metabolic syndrome in rats: Role of nitric oxide and uric acid[J]. Aoms, 2014, 3: 537-545. doi: 10.5114/aoms.2013.33222
[35]	Wang Y, Meng Q, Zhang X, et al. Life’s Essential 8, Life’s Simple 7 and the odds of hyperuricaemia: Results from the China Multi-Ethnic Cohort Study[J]. Rheumatol Adv Pract, 2023, 8: rkae009. doi: 10.1093/rap/rkae009
[36]	Stefan N, Yki-Järvinen H, Neuschwander-Tetri B A. Metabolic dysfunction-associated steatotic liver disease: Heterogeneous pathomechanisms and effectiveness of metabolism-based treatment[J]. Lancet Diabetes Endocrinol, 2025, 13(2): 134-148. doi: 10.1016/S2213-8587(24)00318-8
[37]	Quek J, Chan K E, Wong Z Y, et al. Global prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in the overweight and obese population: A systematic review and meta-analysis[J]. Lancet Gastroenterol Hepatol, 2023, 8(1): 20-30. doi: 10.1016/S2468-1253(22)00317-X
[38]	Pan X, Hong F, Li S, et al. Long-term exposure to ambient PM_2.5 constituents is associated with dyslipidemia in Chinese adults[J]. Ecotoxicol Environ Saf, 2023, 263: 115384. doi: 10.1016/j.ecoenv.2023.115384
[39]	Xie X, Guo B, Xiao X, et al. Healthy dietary patterns and metabolic dysfunction-associated fatty liver disease in less-developed ethnic minority regions: A large cross-sectional study[J]. BMC Public Health, 2022, 22(1): 118. doi: 10.1186/s12889-021-12486-x
[40]	张霓裳. 云南汉族、白族和彝族生命早期饥荒暴露与成年期代谢相关脂肪性肝病关联研究 [D]; 昆明医科大学, 2023.
[41]	车卓航. 云南白族、彝族与汉族自然人群NAFLD患病率及其影响因素分析 [D]; 昆明医科大学, 2024.
[42]	Fanaei H, Mard S A, Sarkaki A, et al. Gallic acid treats dust-induced NAFLD in rats by improving the liver's anti-oxidant capacity and inhibiting ROS/NFκβ/TNFα inflammatory pathway[J]. Iran J Basic Med Sci, 2021, 24(2): 240-7.
[43]	Owens D R, Gurudas S, Sivaprasad S, Zaidi F, Tapp R, Kazantzis D, Evans L, Thomas RL. IDF diabetes Atlas: A worldwide review of studies utilizing retinal photography to screen for diabetic retinopathy from 2017 to 2024 inclusive. Diabetes Res Clin Pract. 2025, 226: 112346.
[44]	方可云, 米飞, 孟琼, 等. 大理白族自然人群糖尿病患病情况及相关分析[J]. 重庆医科大学学报, 2022, 47(05): 620-5.
[45]	Li S, Guo B, Jiang Y, et al. Long-term exposure to ambient PM_2.5 and its components associated with diabetes: Evidence from a large population-based cohort from China[J]. Diabetes Care, 2023, 46(1): 111-119. doi: 10.2337/dc22-1585
[46]	Wang X, Guo B, Yang X, et al. Role of liver enzymes in the relationship between particulate matter exposure and diabetes risk: A longitudinal cohort study[J]. J Clin Endocrinol Metab, 2022, 107(10): e4086-e4097. doi: 10.1210/clinem/dgac438
[47]	Huang J, Chen G, Zhang Q, et al. Correlation between adipocyte fatty acid binding protein and glucose dysregulation is closely associated with obesity and metabolic syndrome: A cohort of Han Chinese population from Yunnan plateau[J]. Lipids, 2022, 57(4-5): 257-264. doi: 10.1002/lipd.12353
[48]	Luo M, Li T, Sang H. The role of hypoxia-inducible factor 1α in hepatic lipid metabolism[J]. J Mol Med, 2023, 101(5): 487-500. doi: 10.1007/s00109-023-02308-5
[49]	Zhang Z, Hu S, Fan P, et al. The roles of liver inflammation and the insulin signaling pathway in PM_2.5 instillation-induced insulin resistance in wistar rats[J]. Dis Markers, 2021, 2021: 2821673.
[50]	Li J, Li L, Lin T, et al. Dihydromyricetin preserves β-cell function in type 1 diabetes via PI3K/AKT-mediated metabolic reprogramming[J]. Front Nutr, 2025, 12: 1682308. doi: 10.3389/fnut.2025.1682308
[51]	Zeng J, Qian Y, Yang J, et al. Nutritional therapy bridges the critical cut-off point for the closed-loop role of type 2 diabetes and bone homeostasis: A narrative review[J]. Heliyon, 2024, 10(7): e28229. doi: 10.1016/j.heliyon.2024.e28229
[52]	Zhang N, Xiao X, Xu J, et al. Dietary Approaches to Stop Hypertension (DASH) diet, Mediterranean diet and blood lipid profiles in less-developed ethnic minority regions[J]. Br J Nutr, 2022, 128(6): 1137-1146. doi: 10.1017/S0007114521004013
[53]	Xiao X, Qin Z, Lv X, et al. Dietary patterns and cardiometabolic risks in diverse less-developed ethnic minority regions: Results from the China Multi-Ethnic Cohort (CMEC) Study[J]. Lancet Reg Health West Pac, 2021, 15: 100252.
[54]	Zare P, Bideshki M V, Sohrabi Z, et al. Effect of Dietary Approaches to Stop Hypertension (DASH) diet on lipid profile in individuals with overweight/obesity: A GRADE-assessed systematic review and meta-analysis of clinical trials[J]. Nutr Metab Cardiovasc Dis, 2025, 35(9): 104057. doi: 10.1016/j.numecd.2025.104057
[55]	Michielsen C C J R, Hangelbroek R W J, Feskens E J M, et al. Disentangling the effects of monounsaturated fatty acids from other components of a Mediterranean diet on serum metabolite profiles: A randomized fully controlled dietary intervention in healthy subjects at risk of the metabolic syndrome[J]. Molecular Nutrition Food Res, 2019, 63(9): 1801095. doi: 10.1002/mnfr.201801095
[56]	Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023 [J]. J Am Coll Cardiol, 2025, 86(22): 2167-2243.
[57]	Guo Y, Zheng W, Yue T, et al. GCH1 contributes to high-altitude adaptation in Tibetans by regulating blood nitric oxide[J]. J Genet Genom, 2025, S1673-8527(25): 00114-6.
[58]	张小乔. 云南高原偏寒地区汉族自然人群高血压患病现况及影响因素研究 [D]; 昆明医科大学, 2022.
[59]	郝歌. 云南世居汉族、白族和彝族高血压与肠道菌群及代谢物的关联研究 [D]; 昆明医科大学, 2023.
[60]	张小乔, 汪艳蛟, 米飞, et al. 云南高原偏寒地区汉族高血压患病现况及其影响因素分析[J]. 实用预防医学, 2022, 29(09): 1093-7.
[61]	曾素素, 孟琼, 张雪辉, 等. 云南楚雄30~79岁彝族居民健康生活方式现状及其影响因素分析[J]. 中国公共卫生, 2022, 38(07): 876-8.
[62]	Chen J, Zuo H, Wu X, et al. Diverse associations between adiposity and blood pressure among 80, 000 multi-ethnic Chinese adults[J]. BMC Public Health, 2023, 23(1): 298. doi: 10.1186/s12889-023-15224-7
[63]	Yu B, Yin J, Yu P, et al. Unveiling relationships of human instinctive behaviors and blood pressure in Chinese adults: A network analysis[J]. Public Health, 2025, 238: 289-297. doi: 10.1016/j.puhe.2024.12.020
[64]	熊佳, 刘冉, 黄雪娟, 等. 基于16S rDNA测序分析云南高原世居汉族高血压患者肠道菌群的差异[J]. 广西医科大学学报, 2024, 41(06): 926-33.
[65]	Dong W, Ma L, Huang Q, et al. Gut microbiome alterations in pulmonary hypertension in highlanders and lowlanders[J]. ERJ Open Res, 2023, 9(3): 617-2022.
[66]	Goldfarb-Rumyantzev A S, Alper S L. Short-term responses of the kidney to high altitude in mountain climbers[J]. Nephrol Dial Transplant, 2014, 29(3): 497-506. doi: 10.1093/ndt/gft051
[67]	Wang Y, Mi F, Zhang Q, et al. Effect of life’s essential 8 and exposure to solid fuels for cooking on cardiovascular disease risk[J]. Can J Cardiol, 2025, 41(10): 1946-1954.
[68]	Yang S, Yu R, Yang F, et al. Mediation role of gut microbiota in the association between ambient fine particulate matter components and cardiovascular disease: Evidence from a China cohort[J]. Environ Res, 2025, 275: 121421. doi: 10.1016/j.envres.2025.121421
[69]	Chen X, Wang Y, Mi F, et al. Higher Life’s Essential 8 score is associated with lower risk of kidney stones in Chinese adults: A cross-sectional study[J]. BMC Public Health, 2025, 25(1): 3732. doi: 10.1186/s12889-025-24499-x
[70]	Dai Y, Yin J, Li S, et al. Long-term exposure to fine particulate matter constituents in relation to chronic kidney disease: Eridence from a large population-based study in China[J]. Environ Geochem Health, 2024, 46(5): 174. doi: 10.1016/j.heliyon.2024.e32497
[71]	陈睿, 楚红, 李鹏飞, 等. 大气颗粒物对慢性肾脏病影响的研究进展[J]. 生物医学转化, 2022, 3(02): 2-8.
[72]	Dai Y, Yin J, Li S, et al. Long-term exposure to fine particulate matter constituents in relation to chronic kidney disease: Evidence from a large population-based study in China[J]. Environ Geochem Health, 2024, 46(5): 174. doi: 10.1007/s10653-024-01949-w
[73]	刘雨寒. 生命早期饥荒暴露与成年期焦虑抑郁患病的关联研究 [D]; 昆明医科大学, 2024.
[74]	Hou Z, Chen Y, Sun Y, et al. Sleep duration and insomnia with comorbid depression and anxiety symptoms in Chinese adults: A cross-sectional study[J]. Nat Sci Sleep, 2023, 15: 1079-1091. doi: 10.2147/NSS.S440584
[75]	Bai H, Wang Y, Liu Y, et al. Early-Life famine exposure and the risk of depression and anxiety in adulthood: Evidence from the China Multi-Ethnic Cohort (CMEC)[J]. BMC Psychiatry, 2025, 25(1): 967. doi: 10.1186/s12888-025-07375-1
[76]	Shen L, Li C, Wang Z, et al. Early-life exposure to severe famine is associated with higher methylation level in the IGF2 gene and higher total cholesterol in late adulthood: The Genomic Research of the Chinese Famine (GRECF) study[J]. Clin Epigenet, 2019, 11(1): 88. doi: 10.1186/s13148-019-0676-3
[77]	Eichenauer H, Ehlert U. The association between prenatal famine, DNA methylation and mental disorders: A systematic review and meta-analysis[J]. Clin Epigenet, 2023, 15(1): 152. doi: 10.1186/s13148-023-01557-y
[78]	Zhang J, Wang S, Zhang X, et al. Mediating role of social capital on the association between negative life events and quality of life among adults in China: A population-based study[J]. Front Public Health, 2022, 10: 987579. doi: 10.3389/fpubh.2022.987579
[79]	Wang Y X, Farland L V, Gaskins A J, et al. Endometriosis and uterine fibroids and risk of premature mortality: Prospective cohort study[J]. Bmj, 2024, 387: e078797. doi: 10.1136/bmj-2023-078797
[80]	Sun Y, Han X, Hou Z, et al. Association between leisure sedentary behaviour and uterine fibroids in non-menopausal women: A population-based study[J]. BMJ Open, 2023, 13(12): e073592. doi: 10.1136/bmjopen-2023-073592
[81]	Yin J, Meng Q, Feng Y. Progress towards global nutrition targets and future directions[J]. Lancet, 2025, 406(10505): 807-808.
[82]	Zeng D, Li H, Car J, et al. Transforming Chinese cohort studies through artificial intelligence: A new era of population health research[J]. Bmj, 2025, 391: e082568. doi: 10.1136/bmj-2024-082568
[83]	Lyu G, Ye W, Gao M, et al. Building sustainable cohort studies in China: A hybrid model for public health research[J]. Bmj, 2025, 391: e082567. doi: 10.1136/bmj-2024-082567
[84]	Ji J S, Smith G D, Clark J. Enhancing cohort studies in China and international collaboration[J]. Bmj, 2025, 391: r2026. doi: 10.1136/bmj.r2026

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