Efficacy Observation of Lower Limb Exoskeleton Rehabilitation Robot Combined with Balance Assessment and Training System in the Treatment of Post-Cerebral Infarction Balance Dysfunction

Chuangguo LI; Jing LIU; Qingtian MENG; Rongbiao HUANG; Zhihong ZHENG; Pan CHENG

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Chuangguo LI, Jing LIU, Qingtian MENG, Rongbiao HUANG, Zhihong ZHENG, Pan CHENG. Efficacy Observation of Lower Limb Exoskeleton Rehabilitation Robot Combined with Balance Assessment and Training System in the Treatment of Post-Cerebral Infarction Balance Dysfunction[J]. Journal of Kunming Medical University.

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Efficacy Observation of Lower Limb Exoskeleton Rehabilitation Robot Combined with Balance Assessment and Training System in the Treatment of Post-Cerebral Infarction Balance Dysfunction

1.
Department of Rehabilitation Medicine，Longgang District People’s Hospital，Shenzhen Guangdong 518100
2.
Department of Rehabilitation Medicine，Yantian District People’s Hospital，Shenzhen Guangdong 518081，China

Received Date: 2025-11-05
Available Online: 2026-01-08

Abstract

Abstract

Objective To explore the clinical efficacy of the lower extremity exoskeleton rehabilitation robot combined with the balance assessment training system in improving balance dysfunction in patients after cerebral infarction. Methods A total of 126 patients with stable cerebral infarction who were hospitalized in Longgang District People's Hospital of Shenzhen from January 2024 to December 2024 were included. According to the computer random number method, the patients were divided into the lower extremity exoskeleton rehabilitation robot group （n = 42）, the balance assessment and training system group （n = 42）, and the comprehensive treatment group （n = 42）. The clinical data, clinical efficacy, relevant parameters of balance test before and after treatment, electromyography characteristics, berg balance scale （BBS）, and Fugl-Meyer assessment of the three groups of patients were compared. Indicators such as FMA, barthel index （BI）, and montreal cognitive assessment （MoCA）. The main effect test was used to analyze the influence of time and treatment methods on the relevant parameters of the balance test and the electromyographic characteristics. Correlation analysis was conducted on the BBS, FMA, BI, MoCA scores before and after treatment, as well as the parameters related to the balance test and the electromyographic characteristics. The difference-in-differences model was adopted to analyze the scores of BBS, FMA, BI and MoCA. Results The total effective rate of the lower limb exoskeleton rehabilitation robot group was 71.43%, that of the balance assessment and training system group was 76.19%, and that of the comprehensive treatment group was 95.24%, which was significantly higher than the other two groups （P < 0.05）. The balance test-related parameters and electromyographic characteristics of the three groups of patients before and after treatment were compared. After treatment, the balance test-related parameters, AEMG and MPF decline rates of the three groups of patients all showed a downward trend, while the complexity showed an upward trend （P < 0.05）, and the difference in the comprehensive treatment group was significant （P < 0.05）. After treatment, the scores of BBS, FMA, BI and MoCA in the three groups of patients increased significantly （P < 0.05）, and the increase in the scores of the patients in the comprehensive treatment group was more obvious （P < 0.05）. The results of Pearson correlation analysis indicated that the relevant parameters of the balance instrument test and the electromyographic characteristic indicators were all correlated before and after treatment, and each parameter was correlated with the BBS, FMA, BI, and MoCA scores after treatment （P < 0.05）. The results of the difference-in-differences model analysis showed that the group and the interaction effect before and after treatment had a significant impact on the BBS, FMA, BI, and MoCA scores （P < 0.05）. Conclusion Lower limb exoskeleton robots combined with balance training can effectively improve the balance, motor and cognitive functions of patients with cerebral infarction, and it is more accurate, safe and economical.
- Cerebral infarction,
- Balance dysfunction,
- Lower limb exoskeleton rehabilitation robot,
- Balance assessment and training system

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References(29)

References

[1]	Rao Z, Tan W, Wang J, et al. Predictive value of Cmmi-MHR combined with thromboelastography parameters in acute cerebral infarction[J]. BMC Med Imag, 2024, 24(1): 115. doi: 10.1186/s12880-024-01299-0
[2]	Guo S, Lin Y, Ma X, et al. Long-term safety and efficacy of antiplatelet therapy in patients with cerebral infarction with thrombocytopenia[J]. Clin Appl Thromb Hemost, 2021, 27: 1076029620980067.
[3]	王心愿, 邱纪方. 虚拟现实技术促进脑卒中下肢功能及其皮层调控研究进展[J]. 中国康复医学杂志, 2022, 37(1): 131-134. doi: 10.3969/j.issn.1001-1242.2022.01.026
[4]	Su D, Hu Z, Wu J, et al. Review of adaptive control for stroke lower li-mb exoskeleton rehabilitation robot based on motion intention recognition[J]. Front Neurorobot, 2023, 17: 1186175. doi: 10.3389/fnbot.2023.1186175
[5]	刘瑞平, 欧阳钧. 下肢外骨骼康复机器人的发展和应用[J]. 中山大学学报: 医学科学版, 2023, 44(2): 354-360. doi: 10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2023.0222
[6]	Unal A, Altug F, Tikac G, et al. Effectiveness of matrix-rhythm therapy on increased muscle tone, balance and gait parameters in stroke survivors: A single-blinded, randomized, controlled clinical trial[J]. Acta Neurol Belg, 2021, 121(3): 689-699. doi: 10.1007/s13760-020-01391-6
[7]	常万鹏, 张钟文, 杨钰琳, 等. 康复外骨骼机器人对脑卒中下肢运动功能障碍疗效的Meta分析[J]. 中国组织工程研究, 2024, 28(2): 321-328.
[8]	张玉代, 邹双骏, 马莉, 等. 下肢康复机器人联合姿势控制训练对脑卒中患者下肢运动功能的影响[J]. 机器人外科学杂志(中英文), 2025, 6(7): 1192-1197. doi: 10.12180/j.issn.2096-7721.2025.07.020
[9]	曾进胜, 蒲传强. 我国各类主要脑血管病诊断要点演变与更新[J]. 中华神经科杂志, 2019, 52(9): 681-683. doi: 10.3760/cma.j.issn.1006?7876.2019.09.001
[10]	Thamsuwan O, Galvin K, Palmandez P, et al. Commonly used subjective effort scales may not predict directly measured physical workloads and fat-igue in hispanic farmworkers[J]. Int J Environ Res Public Health, 2023, 20(4): 2809. doi: 10.3390/ijerph20042809
[11]	王战斌, 陈思婧. 下肢外骨骼机器人临床康复应用进展[J]. 康复医学, 2021, 39(2): 26-27.
[12]	解二康, 从洋洋, 王瑜元, 等. 基于下肢康复机器人的双任务训练对脑卒中患者下肢运动及步行能力的影响[J]. 中华物理医学与康复杂志, 2024, 46(2): 112-117. doi: 10.3760/cma.j.issn.0254-1424.2024.02.003
[13]	徐冬艳, 王卫宁, 潘力, 等. 基于丰富环境理论的多感官反馈步态训练对脑卒中患者步行功能的效果[J]. 中国康复理论与实践, 2024, 30(5): 526-534.
[14]	张先卓, 吕萌, 罗旭飞, 等. 脑卒中康复临床实践指南推荐意见研究[J]. 中国康复理论与实践, 2020, 26(2): 170-180. doi: 10.3969/j.issn.1006-9771.2020.02.007
[15]	周洪雨, 孟兆祥, 金星, 等. 卒中后认知障碍患者的执行功能特征及其早期预测标志物的探索[J]. 中华物理医学与康复杂志, 2024, 46(6): 518-523.
[16]	许明珠, 林润, 温华能, 等. 基于表面肌电图分析靳三针结合镜像疗法治疗脑梗死下肢功能障碍的效果研究[J]. 中国全科医学, 2023, 26(17): 7.
[17]	Du X, Liu Q, Li Q, et al. Prognostic value of cerebral infarction coeffici-ent in patients with massive cerebral infarction[J]. Clin Neurol Neurosurg, 2020, 196: 106009. doi: 10.1016/j.clineuro.2020.106009
[18]	Liu S, Yu H, Wang Z, et al. Correlation analysis of balance function with plantar pressure distribution and gait parameters in patients with cerebral infarction in the basal ganglia region[J]. Front Neurosci, 2023, 17: 1099843. doi: 10.3389/fnins.2023.1099843
[19]	Bian M, Shen Y, Huang Y, et al. A non-immersive virtual reality-based i-ntervention to enhance lower-extremity motor function and gait in patie-nts with subacute cerebral infarction: A pilot randomized controlled trial with 1-year follow-up[J]. Front Neurol, 2022, 13: 985700. doi: 10.3389/fneur.2022.985700
[20]	张凤林, 舒红燕, 任蕾蕾, 等. 改良五禽戏治疗老年脑卒中患者步态及平衡功能障碍的疗效及基于功能磁共振的脑机制研究[J]. 实用医学杂志, 2023, 39(9): 1174-1178.
[21]	董柯, 练涛. 经颅直流电刺激对脑卒中患者平衡功能影响的研究进展[J]. 中国康复医学杂志, 2022, 37(10): 1425-1429.
[22]	王海静, 高崇, 李庆雯. 运动双任务训练对慢性脑卒中患者平衡功能的影响[J]. 中国康复医学杂志, 2021, 36(9): 1111-1117.
[23]	朱志伟, 唐春霞, 徐立娟, 等. 脑卒中患者下肢外骨骼康复机器人步态规划与运动学仿真[J]. 机械设计与制造, 2022, 1(1): 247-250+256.
[24]	李明, 李慧, 喻洪流. 下肢外骨骼康复机器人的分类及其应用现状[J]. 生物医学工程学杂志, 2024, 41(4): 833-839.
[25]	何蕾, 柴双双, 陈亚平. 平衡评估训练系统对脑卒中后平衡功能的康复效果[J]. 中国康复理论与实践, 2021, 27(7): 5.
[26]	王亚楠, 刘西花. 脑卒中偏瘫患者主观和客观平衡功能测量的相关性及预测效能[J]. 中国康复理论与实践, 2023, 29(8): 890-895.
[27]	张明霞, 黄婷婷, 黎力生, 等. 经颅磁刺激治疗联合任务导向性训练对老年脑梗死患者肢体功能及日常生活能力的影响[J]. 中国老年学杂志, 2022, 42(20): 5057-5059.
[28]	Tatsuno H, Hamaguchi T, Sasanuma J, et al. Does a combination treatme-nt of repetitive transcranial magnetic stimulation and occupational therapy improve upper limb muscle paralysis equally in patients with chronic stroke ca-used by cerebral hemorrhage and infarction? A retrospective cohort study[J]. Medicine, 2021, 100(24): e26339. doi: 10.1097/MD.0000000000026339
[29]	Liang F F, Liu X X, Liu J H, et al. Effect of infarct location and volu-me on cognitive dysfunction in elderly patients with acute insular cerebral infarction[J]. World J Psychiatry, 2024, 14(8): 1190-1198. doi: 10.5498/wjp.v14.i8.1190

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